Tag: M.W=50-100

Imidazole based anticancer drug find applications in cancer chemotherapy. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). Recommanded Product: 1H-Imidazole-2-carbaldehyde.

Xie, Jialin;Xu, Wentao;Song, Hongjian;Liu, Yuxiu;Zhang, Jingjing;Wang, Qingmin research published 《 Synthesis and Antiviral/Fungicidal/Insecticidal Activities Study of Novel Chiral Indole Diketopiperazine Derivatives Containing Acylhydrazone Moiety》, the research content is summarized as follows. On the basis of the mechanism of acylhydrazone compounds inhibiting the assembly of TMV CP and the unique structural characteristics of diketopiperazine ring, a series of optically pure indole diketopiperazine acylhydrazone were designed and synthesized. In order to systematically study the effect of the spatial configuration of the compounds on the antiviral activity, four compounds with different spatial configurations at C6 and C12a were also prepared The bioassay results indicated that most of these new compounds displayed moderate to good antiviral activity, among which compounds I, II, III, IV, V, and VI showed a significantly higher activity than that of com. ribavirin. An in-depth structure-activity relationship investigation showed that the spatial conformation was one of the most important factors in adjusting antiviral activity; the research results provided information about the possible optimum configuration for interaction of this mol. with its target protein. At the same time, these new compounds also exhibited broad-spectrum fungicidal activities against 14 kinds of phytopathogenic fungi. What’s more, some of these compounds exhibited good insecticidal activity to Plutella xylostella and Culex pipiens pallens.

Recommanded Product: 1H-Imidazole-2-carbaldehyde, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents. Reference of 10111-08-7.

Xie, Ting;Wang, Guo-Qiang;Wang, Ya-Wen;Rao, Weidong;Xu, Haiyan;Li, Shuhua;Shen, Zhi-Liang;Chu, Xue-Qiang research published 《 Selective Quadruple C(sp³)-F Functionalization of Polyfluoroalkyl Ketones》, the research content is summarized as follows. An unprecedented coupling-aromatization-cyclization reaction of polyfluorinated ketones with diverse N- and S-nucleophiles that formed regio-defined perfluoroalkylated naphtho[1,2-b]furan/benzofuran derivatives by harnessing Co-promoted distinctive quadruple C(sp³)-F bonds cleavage relay. This chem. involving controlled and successive selective defluorination at heteronuclear centers greatly contributed to the preparation of drug-like heterocycles as well as the late-stage elaboration of biorelevant compounds Controlled experiments and DFT theor. studies revealed that the combination of cheap cobalt salt with Cs₂CO₃ enabled expeditious C-F functionalization.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Reference of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Product Details of C5H8N2.

Xing, Yi;Geng, Kang;Chu, Xiaomeng;Wang, Chenyi;Liu, Lei;Li, Nanwen research published 《 Chemically stable anion exchange membranes based on C2-Protected imidazolium cations for vanadium flow battery》, the research content is summarized as follows. Imidazolium-based anion exchange membranes (AEMs) are attractive as the separator for vanadium redox flow battery (VFB) application. However, the lack of fundamental understanding of the correlations between imidazolium chem. structure and their phys. properties as well as cell performance constraints the design of advanced AEMs in VFBs. In this work, by designing the “clickable” imidazolium compounds from C2-Me or C2-Ph substituted imidazolium to C2-Ph substituted benzimidazolium, a series of PSf-based AEMs having pendant C2-protected imidazolium derivatives were prepared by efficient CuAAC reaction to explore how the nature of C2 substitution affected the electrochem. property of AEMs and the resulting VFB performance. Interestingly, PSf-MIm with C2-Me protected imidazolium group showed lowest area resistance (0.3 Ω cm², IEC = 1.66 meq./g) in 3 M H₂SO₄ aqueous solution but unfavorable vanadium permeability due to its highest swelling ratio. The introduction of bulky C2-Ph substituted benzimidazolium led to the distinct microphase separation in PSf-PhBIm membrane, and thus reduced water uptake, high vanadium selectivity, and comparable conductivity were observed As a result, the single VFB with PSf-MIm-1.2 membrane exhibited better electrochem. performance with a coulombic efficiency (CE) of 97.0%, and an energy efficiency (EE) of 82.4% at a c.d. of 120 mA/cm², higher than those of Nafion N115 membrane (EE = 75.5%) and unsubstituted imidazolium-based AEMs (EE = 80.6%). More importantly, both ex situ stability testing in 1.5 M (VO₂)₂SO₄/3 M H₂SO₄ solution for 90 days and in situ cycling performance at a c.d. of 120 mA/cm² demonstrated that the chem. structure of C2-substituted imidazolium based AEMs remained intact after stability tests as confirmed by NMR anal., while significant degradation was found for unsubstituted PSf-Im membrane via possible nucleophilic addition mechanism. Therefore, the VFB with PSf-MIm membrane showed the best long-term durability with only 34.1% loss in EE for 3638 h of operating (4800 cycles). This work not only fills the knowledge gap on the structure-property relationship of imidazolium-based AEMs for VFB application, but also gives us new directions to design stable AEMs for durable VFBs.

Product Details of C5H8N2, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., 1739-84-0.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole based anticancer drug find applications in cancer chemotherapy. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). Synthetic Route of 3034-50-2.

Xing, Yingying;Dong, Fengying;Yin, Xiangcong;Wang, Liang;Li, Shuai-Shuai research published 《 Facile Construction of 3,4-dihydro-2H-1,2,4-Benzothiadiazine 1,1-Dioxides via Redox-Neutral Cascade Condensation/[1,7]-Hydride Transfer/Cyclization》, the research content is summarized as follows. The benzothiadiazine 1,1-dioxides were highly efficiently constructed via a BF₃.Et₂O promoted redox-neutral cascade condensation/[1,7]-hydride transfer/cyclization, which featured novel substrate skeletons, broad substrate scope, [1,7]-hydride transfer manner, metal-free conditions and the facile introduction of aryl, heteroaryl, allyl and propargyl groups etc.

Synthetic Route of 3034-50-2, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, 3034-50-2.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole is a five-membered heterocyclic moiety that possesses three carbon, two nitrogen, four hydrogen atoms, and two double bonds. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is also known as 1, 3-diazole. It contains two nitrogen atoms, in which one nitrogen bear a hydrogen atom, and the other is called pyrrole type nitrogen. Reference of 10111-08-7.

Xiong, Wu-Lin;Peng, Xiao-Chong;Zhong, Ren-Yuan;Zheng, Jianwei;Duo, Shuwang;Gong, Shan-Shan;Sun, Hong-bin;Sun, Qi research published 《 Construction of a Clock Catalytic System: Highly Efficient and Self-Indicating Synthesis of Benzoheterocycles at Ambient Temperature》, the research content is summarized as follows. Inspired by the mechanism of the clock reaction, a novel phosphomolybdenum blue (PMB) clock catalytic system was constructed for a highly efficient synthesis of benzimidazoles and benzothiazoles simply at ambient temperature The PMB clock catalytic system exhibited a sharp decoloration event to announce the depletion of the intermediate constraint, making this synthetic approach self-indicating and TLC-free. XPS and ³¹P NMR anal. of PMB catalyst showed that only two Mo⁶⁺ atoms were reduced to Mo⁵⁺ atoms in the Keggin structure due to the moderate reducibility of benzimidazoline and benzothiazoline intermediates. Thus,the active Keggin-type POM cluster could be well maintained in DMSO during the redox cycling of phosphomolybdic acid (PMA) and PMB. The ¹H NMR tracing experiment not only confirmed the proposed reaction mechanism but also showed that PMB exerts Lewis acid catalytic activity at the early phase of the reaction other than the expected redox catalytic activity.

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Reference of 10111-08-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 3034-50-2, formula is C4H4N2O, Name is Imidazole-4-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Formula: C4H4N2O.

Xu, Chang-Jiang;Du, Wei;Albrecht, Lukasz;Chen, Ying-Chun research published 《 Lewis Basic Amine Catalyzed Aza-Michael Reaction of Indole- and Pyrrole-3-carbaldehydes》, the research content is summarized as follows. 3-Formyl substituted indoles or pyrroles can form HOMO-raised dearomative aza-dienamine-type intermediates with secondary amines, which can undergo direct aza-Michael addition to β-trifluoromethyl enones to afford N-alkylated products efficiently, albeit with low to fair enantioselectivity. In addition, similar asym. aza-Michael additions of these heteroarenes and crotonaldehyde are realized under dual catalysis of chiral amines, and the adducts are obtained with moderate to good enantioselectivity.

3034-50-2, 1H-Imidazole-4-carbaldehyde, also known as 1H-Imidazole-4-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
The starting material for a practical synthesis of a potent C17,20-lyase inhibitor. The lyase is a key enzyme in androgen biosynthesis as well as a target for treatment of androgen-dependent prostate cancer. Used to synthesize potent antimalarial drug.
1H-Imidazole-4-carbaldehyde is a chemical compound that has been shown to bind to the glucocorticoid receptor. It was synthesized by reacting 1,2-diaminobenzene with formaldehyde and then hydrolyzing the intermediate imidazolium salt, which is stable in acidic solutions. The complex can be prepared by mixing two solutions of imidazole and trifluoroacetic acid. The ligand has a redox potential of -0.1 V (vs NHE). This means it can be oxidized to the carbonyl group or reduced back to the imidazole ring. The compound is stable in neutral solution and forms stable complexes with metal ions such as Cu+, Fe3+, and Zn2+. It also coordinates well with oxygen atoms, nitrogen atoms, and water molecules. 1H-Imidazole-4-carbaldehyde has been shown to bind to glucocortic, Formula: C4H4N2O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Formula: C4H4N2O.

Wang, Huanhuan;Bao, Yuheng;Qiu, Huiqiang;Tong, Weijun research published 《 Encapsulation of Methylene Blue in Zeolitic Imidazolate Framework-90 Nanoparticles to Protect Its Photodynamic Activity》, the research content is summarized as follows. Methylene blue (MB) is widely used as a photosensitizer in photodynamic therapy applications. However, it is easily reduced by reductases in biol. environments, which hampers its further applications. Here, we developed a one-pot method to synthesize MB-encapsulated and poly(vinylpyrrolidone) (PVP)-modified zeolitic imidazolate framework-90 (ZIF-90) nanoparticles (MB@ZIF-90/PVP NPs). The NPs show intact crystalline structure with improved colloidal dispersity and stability both in water and in the medium for cell culture. The size of the enzymes is much larger than the pore size of ZIF-90; thus, the access of reductive enzymes to encapsulated MB is prohibited, resulting in the protection of MB′s photodynamic activity. Furthermore, cell experiments confirm that MB@ZIF-90/PVP NPs have lower dark cytotoxity than equivalent free MB but can efficiently induce photodynamic damage to tumor cells even in the presence of reductive enzymes upon light irradiation

10111-08-7, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., Formula: C4H4N2O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. Their solubility in alcohol is lower than that in water and decreases with increasing molecular weight of the alcohols . Recommanded Product: 1H-Imidazole-2-carbaldehyde.

Wang, Jian Hua;Liu, Yao Ming;Chao, Jian Bin;Wang, Yu;Wang, Hui;Shuang, Shao Min research published 《 A phenazine-imidazole based ratiometric fluorescent probe for Cd²⁺ ions and its application in in vivo imaging》, the research content is summarized as follows. A new phenazine-imidazole based Schiff base (PIS) fluorescent probe has been developed for the ratiometric detection of Cd²⁺ ions in aqueous media at physiol. pH. PIS upon binding with Cd²⁺ ions shows red shifted fluorescence and thereby, permits ratiometric detection of Cd(II) ions. A detection limit down to 2.10 x 10^-8 M was determined for Cd²⁺ quantitation. Also, the accompanying apparent fluorescence color change (from yellow to orange red) is noticeable to the naked eye under a UV-lamp. The sensing mechanism could be attributed to the 1 : 1 PIS-Cd complexation, followed by extension of the conjugation due to better planarity and modulation of the charge transfer efficiency in the probe. This was complemented by solvatochromism and d. functional theory calculations Furthermore, PIS was used to detect Cd²⁺ in Oxya chinensis cells, zebrafish larvae and live tissues of Arabidopsis thaliana under a fluorescence microscope, showing great potential in analyzing living biosystems.

Recommanded Product: 1H-Imidazole-2-carbaldehyde, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Imidazole based anticancer drug find applications in cancer chemotherapy. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC). Category: imidazoles-derivatives.

Wang, Jian Hua;Liu, Yao Ming;Chao, Jian Bin;Wang, Hui;Wang, Yu;Shuang, ShaoMin research published 《 A simple but efficient fluorescent sensor for ratiometric sensing of Cd²⁺ and bio-imaging studies》, the research content is summarized as follows. A very simple schiff base fluorescent probe (NIS) was facilely prepared via a one-step, one-pot condensation reaction between 2, 3-naphthalenediamine and imidazole-2-carboxaldehyde. Among common biol. relevant metal ions, NIS can selectively recognize Cd²⁺ via ratiometric fluorescence signal. The chelation of NIS with the Cd²⁺ ions resulted in a fluorescence enhancement together with a blue shift (∼74 nm) in the emission maxima, presumably due to the combined effects of ICT (internal charge transfer) and CHEF (chelation-enhanced fluorescence). The binding stoichiometry of NIS to Cd²⁺ is 1:1 and the fluorescence intensity ratio (F₃₉₈/F₄₇₂) changes allow a ratiometric detection of Cd²⁺ with the detection limit of 3.87 × 10^-7 M. Under fluorescence confocal microscope and via two emission channels, the probe is capable to detect Cd²⁺ ions in Human liver cancer cells (SMMC-7721), zebrafish and live tissues of Arabidopsis thaliana, demonstrating its applicability for detecting Cd²⁺ ions in different biol. context with low toxicity.

Category: imidazoles-derivatives, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . 1739-84-0, formula is C5H8N2, Name is 1,2-Dimethyl-1H-imidazole. In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with an increase of the alkyl chain length of the alcohols. SDS of cas: 1739-84-0.

Wang, Jian;Wu, Junshuang;Wu, Wenqing;Tong, Jing research published 《 Estimation of the polarity and prediction of the molar surface Gibbs energy for amino acid ionic liquids – [C₄Dmim][Gly] and [C₄Dmim][Ala]》, the research content is summarized as follows. 1-Butyl-2,3-dimethylimidazolium glycine ([C₄Dmim][Gly]) and 1-butyl-2,3-dimethylimidazolium alanine ([C₄Dmim][Ala]) were synthesized by neutralization method and characterized by ¹H NMR and ¹³C NMR spectrum. The exptl. values of the d., surface tension and refractive index of two amino acid ionic liquids were measured by standard addition method. Firstly, the polarity coefficients of [C₄Dmim][Gly] and [C₄Dmim][Ala] were calculated by polarity coefficient (P), and the polarity trend of other ionic liquids (ILs) was predicted. For the same anion, the polarity values of the same series of ILs decrease with increasing carbon chain length, and the anion species also affect the polarity of ILs. Secondly, according to the relationship between the slope of the new Eotvos empirical equation and the molar surface entropy (s), the polarity values of other ILs were also estimated and the conclusion obtained was basically consistent with polarity coefficient Furthermore, the predicted molar surface Gibbs energy values of samples were obtained by the new Eotvos empirical equation, and the predicted values were highly consistent with the corresponding exptl. values.

1739-84-0, 1,2-Dimethylimidazole is used in the synthesis of 1,2-dimethyl-3-n-butylimidazoliumchloride and 1,2-dimethyl-3-n-propylimidazolium chloride. It also can be used in the synthesis of 1-(2-methoxyethyl)-2,3-dimethylimidazolium chloride and hexafluorophosphate salts.
1,2-Dimethylimidazole is a heterocyclic compound that contains nitrogen and carbon. It can be produced by the reaction between glyoxal and fatty acid in the presence of a base. 1,2-Dimethylimidazole has been shown to have biological properties such as an antioxidant effect. It is also used as a chemical intermediate for production of other chemicals such as 2-methylimidazole and 3-methylimidazole. 1,2-Dimethylimidazole has been shown to react with metal carbonyls to produce methylimines, which are useful intermediates in organic synthesis. The reaction mechanism involves hydrogen bonding and steric interactions between the imidazole ring and the metal carbonyl reactant., SDS of cas: 1739-84-0

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem