Tag: 600-700

In 2013,Chemical Communications (Cambridge, United Kingdom) included an article by Visbal, Renso; Laguna, Antonio; Gimeno, M. Concepcion. Electric Literature of C27H38AuClN2. The article was titled 《Simple and efficient synthesis of [MCl(NHC)] (M = Au, Ag) complexes》. The information in the text is summarized as follows:

A facile and efficient synthetic route leading to catalytically relevant N-heterocyclic carbene (NHC) gold complexes is described. The method consists of one pot synthesis starting from readily available imidazolium salts and [AuCl(tht)], in the presence of K2CO3. Using the same protocol NHC silver complexes have been synthesized starting from AgNO3. In the experimental materials used by the author, we found Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I)(cas: 852445-84-2Electric Literature of C27H38AuClN2)

Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I)(cas: 852445-84-2) belongs to imidazoles.Imidazole rings are part of unnatural cyclic peptides and are used as ester isosteres in peptidomimetic studies.
However, the application of imidazoles is not limited to the field of peptides and peptidomimetics. Electric Literature of C27H38AuClN2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Isolable, gold carbonyl complexes supported by N-heterocyclic carbenes》 was published in Chemical Communications (Cambridge, United Kingdom) in 2011. These research results belong to Dash, Chandrakanta; Kroll, Peter; Yousufuddin, Muhammed; Dias, H. V. Rasika. Safety of Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I) The article mentions the following:

Cationic gold carbonyl complexes supported by N-heterocyclic carbene ligands, 1,3-bis(2,6-diisopropylphenyl)imidazolin-2-ylidene (SIDipp) and 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene (IDipp), have been synthesized. [(SIDipp)Au(CO)][SbF6] has a linear, two-coordinate gold center. [(SIDipp)Au(CO)][SbF6] and [(IDipp)Au(CO)][SbF6] display νCO values at 2197 and 2193 cm-1, resp. Computational studies on [(SIMe)Au(CO)]+ indicate the presence of a strong Au(I)-CO bond. The experimental part of the paper was very detailed, including the reaction process of Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I)(cas: 852445-84-2Safety of Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I))

Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I)(cas: 852445-84-2) belongs to imidazoles.Imidazole rings are part of unnatural cyclic peptides and are used as ester isosteres in peptidomimetic studies.
Safety of Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I) However, the application of imidazoles is not limited to the field of peptides and peptidomimetics.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Computed Properties of C27H38AuClN2On September 16, 2020 ,《AuI-Catalyzed Hydroalkynylation of Haloalkynes》 was published in Journal of the American Chemical Society. The article was written by Garcia-Fernandez, Pedro D.; Iglesias-Siguenza, Javier; Rivero-Jerez, Paula S.; Diez, Elena; Gomez-Bengoa, Enrique; Fernandez, Rosario; Lassaletta, Jose M.. The article contains the following contents:

The AuI-catalyzed reaction between terminal alkynes and aromatic haloalkynes proceeds through divergent pathways depending on the nature of the catalyst counteranion. Thus, cationic complexes containing strongly basic NHC ligands and noncoordinating anions such as BArF4 catalyze the cis haloalkynylation of the terminal alkyne, whereas introduction of a weakly basic triflate counteranion results in the stereoselective hydroalkynylation of the haloalkyne, yielding haloenyne products in good yields and complete trans selectivity. Exptl. and computational studies suggest that the hydroalkynylation reaction takes place via nucleophilic attack of the terminal alkyne to the C2 carbon of the activated haloalkyne, assisted by a concerted proton abstraction by the triflate, and that the protodeauration is the turnover-limiting step, in agreement with an observed primary kinetic isotope effect. In the part of experimental materials, we found many familiar compounds, such as Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I)(cas: 852445-84-2Computed Properties of C27H38AuClN2)

Chloro{1,3-bis[2,6-bis(1-methylethyl)phenyl]-4,5-dihydroimidazol-2-ylidene}gold(I)(cas: 852445-84-2) belongs to imidazoles.Although other azole heterocycles are ubiquitous in a wide range of biologically active natural products, imidazole rings occur predominantly in the natural amino acid histidine. Computed Properties of C27H38AuClN2 In addition, imidazole rings are part of unnatural cyclic peptides and are used as ester isosteres in peptidomimetic studies.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem