Tag: 200-300

One-step radiation synthesis of novel star-shaped polymeric ionic liquid-POSS gel electrolytes with high ionic conductivity and mechanical properties for supercapacitor was written by Shi, Mengni;Lin, Tingrui;Wang, Yue;Hu, Yang;Peng, Jing;Li, Jiuqiang;Zhai, Maolin. And the article was included in Journal of Materials Science in 2020.Synthetic Route of C9H15F6N2P This article mentions the following:

Polymeric ionic liquids (PILs) not only have the unique properties of ionic liquid, but also possess diverse mech. properties of polymers. Due to their safety and conductivity, PILs-based gel polymer electrolytes (GPEs) are the promising candidates for the design of the devices. Here, we reported a facile approach to synthesize novel star-shaped GPE (named PIL-POSS-Li GPE) based on 1-vinyl-3-butylimidazolium hexafluorophosphate ionic liquid, octavinyl polyhedral oligomeric silsesquioxane (POSS) and LiPF6 solution in one step via gamma-ray radiation. Compared with PIL-Li GPE without POSS, the incorporation of POSS into the PIL-Li GPE can improve properties of PIL-POSS-Li GPE due to the formation of a star-shaped structure, and the as-prepared PIL-POSS-Li GPE showed excellent compressive strength of 1617 kPa, high fracture compression stain of 79% and high ionic conductivity of 3.88 mS cm^-1 at 25掳C. What is more, the PIL-POSS-Li supercapacitor (SC) showed better electrochem. performance than PIL-Li SC. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9Synthetic Route of C9H15F6N2P).

1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Synthetic Route of C9H15F6N2P

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A novel and efficient process for the preparation of zolpidem, an insomnia drug was written by Eswaraiah, P.;Ravi, Kumar Reddy N.;Chakravarthy, I. E.;Prasada, Rao D. E.;Rajendiran, C.. And the article was included in Journal of Chemical and Pharmaceutical Research in 2016.Recommanded Product: 106961-33-5 This article mentions the following:

Zolpidem, is an imidazopyridine group of non-benzodiazepine class drug, used for the treatment of insomnia. Here with presenting a new approach for the synthesis zolpidem without isolation of intermediates. The modified process is efficient, cost effective, simplified work up process and scalable synthesis of zolpidem with reducing cycle time. In the experiment, the researchers used many compounds, for example, N,N-Dimethyl-1-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine (cas: 106961-33-5Recommanded Product: 106961-33-5).

N,N-Dimethyl-1-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine (cas: 106961-33-5) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3鈥揅6) is higher than in water and generally decreases with a Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Recommanded Product: 106961-33-5

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis, docking and biological activity of various substituted zolpidem based GABA_A inhibitors endowed potent hypnotic and sedative activity was written by Aanandhi, M. Vijey;Bhattacherjee, Debojit;Kamalraj, R.. And the article was included in Inventi Impact: Med Chem in 2014.Recommanded Product: N,N-Dimethyl-1-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine This article mentions the following:

Synthesis, characterization, biol. profiling and mol. docking studies were carried out to understand the biol. activity and binding selectivity of the Zolpidem based compounds I (R¹ = 3-CH₃, 4-CH₃, 5-CH₃; R² = NMe₂, diisopropylamine). The study indicates that substituted zolpidem based compounds showed potent phenobarbitone induced hypnosis as well as locomotor activity throughout the study. Compounds I (R¹ = 3-CH₃; R² = NMe₂, diisopropylamine) produced significant reduction in onset and prolongation of sleep duration induced by phenobarbitone. In the second model (locomotor activity in actophotometer) activity was found to be maximum for I (R¹ = 3-CH₃; R² = NMe₂, diisopropylamine) (30 mg/kg), produced 31.2 and 33.2% decrease in locomotor activity, where standard drug phenobarbitone produced 59.37% decrease in activity. Mol. docking studies also concluded the selectivity of compound I (R¹ = 3-CH₃, R² = diisopropylamine) was appreciable in respect to the standard The binding energy and the bond distances of phenobarbitone and compound I (R¹ = 3-CH₃, R² = diisopropylamine) between the target were found to be -7.24 kcal and -6.6 kcal and 2.829 脜 (PRO 85), 1.896 脜 (PHE 78), (LEU 76) resp. The study revealed the possibilities in future research of zolpidem based derivatives for establishment of new generation CNS acting agents. In the experiment, the researchers used many compounds, for example, N,N-Dimethyl-1-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine (cas: 106961-33-5Recommanded Product: N,N-Dimethyl-1-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine).

N,N-Dimethyl-1-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine (cas: 106961-33-5) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3鈥揅6) is higher than in water and generally decreases with a Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Recommanded Product: N,N-Dimethyl-1-(6-methyl-2-(p-tolyl)imidazo[1,2-a]pyridin-3-yl)methanamine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The relationship between the binding of 2-n-alkylbenzimidazoles to rat hepatic microsomal cytochrome P 450 and the inhibition of monooxygenation was written by Dickins, Maurice;Bridges, James W.. And the article was included in Biochemical Pharmacology in 1982.Category: imidazoles-derivatives This article mentions the following:

The binding of an homologous series of 2-n-alkylbenzimidazoles to cytochrome聽P聽450聽聽[9035-51-2] in control, phenobarbitone-, or 20-methylcholanthrene-induced rat hepatic microsomal preparations produced Type I, Type RI, and mixed Type I/RI spectra. Alkyl chain length affected spectral type, as did substrate concentration and microsomal source. An optimal chain length of C₇-C₈ was observed for Type I binding, longer side chains decreasing the affinity. The apparent spectral binding constants for the Type I site only were closely associated with the K_i and I₅₀ values for the inhibition of cytochrome P 450-dependent monooxygenation. From their inhibition properties, even the short chain substituted benzimidazoles also appeared to bind to the Type I site and thus compete for the substrate binding site of cytochrome P 450. In the experiment, the researchers used many compounds, for example, 2-Octylbenzimidazole (cas: 13060-24-7Category: imidazoles-derivatives).

2-Octylbenzimidazole (cas: 13060-24-7) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3鈥揅6) is higher than in water and generally decreases with a Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A Multiscale Simulation Study of Influence of Morphology on Ion Transport in Block Copolymeric Ionic Liquids was written by Zhang, Zidan;Krajniak, Jakub;Ganesan, Venkat. And the article was included in Macromolecules (Washington, DC, United States) in 2021.Synthetic Route of C9H15F6N2P This article mentions the following:

We present results of a multiscale simulation study involving coarse-graining and reverse-mapping steps probing at an atomistic resolution the influence of morphol. on ion transport in block copolymer polymeric ionic liquids We provide a detailed description of the multiscale simulation methodol. and then describe the results in the context of four microphase-separated morphologies: two lamella systems, a cylinder, and a gyroid morphol. For the framework adopted in this study (in which the total number of ions was maintained fixed), morphol. had little influence on the fraction of ions segregating to the interface and the coordination and hopping characteristics of such interfacially present ions. Such results manifested in anion mobilities being insensitive to the morphol. once the dimensionality of the morphol. was accounted for. Overall, our results are consistent with the hypothesis that the mobility of ions in such microphase-separated morphologies, after accounting for the dimensionality effects, can be roughly correlated to a linear superposition based on the fraction of bulk anions, which possess mobilities unperturbed from their values in the conducting homopolymers, and the interfacial anions, which exhibit much lower mobilities. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9Synthetic Route of C9H15F6N2P).

1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Synthetic Route of C9H15F6N2P

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

3,5-Dihydro-imidazo[4,5-d]pyridazin-4-ones: A class of potent DPP-4 inhibitors was written by Eckhardt, Matthias;Hauel, Norbert;Himmelsbach, Frank;Langkopf, Elke;Nar, Herbert;Mark, Michael;Tadayyon, Moh;Thomas, Leo;Guth, Brian;Lotz, Ralf. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2008.HPLC of Formula: 74478-96-9 This article mentions the following:

Systematic variations of the xanthine scaffold in close analogs of development compound BI 1356 led to the class of 3,5-dihydro-imidazo[4,5-d]pyridazin-4-ones which provided, after substituent screening, a series of highly potent DPP-4 inhibitors. In the experiment, the researchers used many compounds, for example, Ethyl 2,4-dibromo-1H-imidazole-5-carboxylate (cas: 74478-96-9HPLC of Formula: 74478-96-9).

Ethyl 2,4-dibromo-1H-imidazole-5-carboxylate (cas: 74478-96-9) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.HPLC of Formula: 74478-96-9

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

CO₂ Responsive Imidazolium-Type Poly(Ionic Liquid) Gels was written by Zhang, Jing;Xu, Dan;Guo, Jiangna;Sun, Zhe;Qian, Wenjing;Zhang, Ye;Yan, Feng. And the article was included in Macromolecular Rapid Communications in 2016.Reference of 915358-85-9 This article mentions the following:

Poly(ionic liquid) (PIL) gels with CO₂ stimulus responsiveness were synthesized through the copolymerization of an imidazolium-type ionic liquid monomer with 2-(di-Me amino) Et methacrylate. Upon bubbling with CO₂ gas, the prepared PIL solution is converted to a transparent and stable gel, which can be turned back to the initial solution state after N₂ bubbling. The reversible sol-gel phase transition behavior is proved by the reversible values of viscosity and ionic conductivity The possible mechanism for such a reversible sol-gel phase transition is demonstrated by NMR, conductivity, and rheol. measurements. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9Reference of 915358-85-9).

1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Reference of 915358-85-9

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

CO₂ Responsive Imidazolium-Type Poly(Ionic Liquid) Gels was written by Zhang, Jing;Xu, Dan;Guo, Jiangna;Sun, Zhe;Qian, Wenjing;Zhang, Ye;Yan, Feng. And the article was included in Macromolecular Rapid Communications in 2016.Reference of 915358-85-9 This article mentions the following:

Poly(ionic liquid) (PIL) gels with CO₂ stimulus responsiveness were synthesized through the copolymerization of an imidazolium-type ionic liquid monomer with 2-(di-Me amino) Et methacrylate. Upon bubbling with CO₂ gas, the prepared PIL solution is converted to a transparent and stable gel, which can be turned back to the initial solution state after N₂ bubbling. The reversible sol-gel phase transition behavior is proved by the reversible values of viscosity and ionic conductivity The possible mechanism for such a reversible sol-gel phase transition is demonstrated by NMR, conductivity, and rheol. measurements. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9Reference of 915358-85-9).

1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Reference of 915358-85-9

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Efficient synthesis of styrene carbonate from CO₂ and styrene oxide using zinc catalysts immobilized on soluble imidazolium-styrene copolymers was written by Qiao, Kun;Ono, Fumitaka;Bao, Quanxi;Tomida, Daisuke;Yokoyama, Chiaki. And the article was included in Journal of Molecular Catalysis A: Chemical in 2009.HPLC of Formula: 915358-85-9 This article mentions the following:

Preparation of zinc catalysts (Zn/PS-IL[X], X = Br^–, Cl^–, BF₄ ^–, and PF₆ ^–) supported on imidazolium-styrene copolymers, as well as their catalytic use for the solvent-free synthesis of styrene carbonate from CO₂ and styrene oxide, are described. Among the catalysts examined, Zn/PS-IL[Br] was proved to be the most efficient. When used in a homogeneous system during the reaction process, Zn/PS-IL[Br] gave a 97.5% yield of product with a TOF value that can be up to about 3800 h^-1. Due to its immiscibility with ethanol, Zn/PS-IL[Br] can be separated like a heterogeneous catalyst through solvent precipitation, and reused at least three times for the reaction without significant loss of activity. In the experiment, the researchers used many compounds, for example, 1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9HPLC of Formula: 915358-85-9).

1-Butyl-3-vinyl-1H-imidazol-3-ium hexafluorophosphate(V) (cas: 915358-85-9) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).HPLC of Formula: 915358-85-9

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem