Tag: 100-200

New membranes based on ionic liquids for PEM fuel cells at elevated temperatures was written by Ye, H.;Huang, J.;Xu, J. J.;Kodiweera, N. K. A. C.;Jayakody, J. R. P.;Greenbaum, S. G.. And the article was included in Journal of Power Sources in 2008.Related Products of 79917-89-8 This article mentions the following:

Proton exchange membrane (PEM) fuel cells operating at elevated temperature, above 120 °C, will yield significant benefits but face big challenges for the development of suitable PEMs. The objectives of this research are to demonstrate the feasibility of the concept and realize [acid/ionic liquid/polymer] composite gel-type membranes as such PEMs. Novel membranes consisting of anhydrous proton solvent H₃PO₄, the protic ionic liquid PMIH₂PO₄, and polybenzimidazole (PBI) as a matrix have been prepared and characterized for PEM fuel cells intended for operation at elevated temperature (120-150 °C). Phys. and electrochem. analyses have demonstrated promising characteristics of these H₃PO₄/PMIH₂PO₄/PBI membranes at elevated temperature The proton transport mechanism in these new membranes has been investigated by Fourier transform IR and NMR spectroscopic methods. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8Related Products of 79917-89-8).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Related Products of 79917-89-8

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Michael adducts in the regioselective synthesis of N-substituted azoles was written by Horvath, Andras. And the article was included in Synthesis in 1995.Quality Control of 7-Methyl-1H-benzo[d]imidazole This article mentions the following:

Michael adducts of azoles (4-phenyl-, 4-methyl-, and 4-nitroimidazole, 4-methylbenzimidazole, 1,2,4-triazole, and theophylline) are shown to be valuable substrates for obtaining the N-substituted derivatives of the parent heterocycles by a quaternization-Hofmann elimination sequence. The effectiveness of the procedure is dependent on the regiochem. outcome of the 1st, N-protective step, i.e. the Michael addition By choosing the appropriate Michael acceptor, alkylating agent, and deprotection conditions, the thermodynamically less stable regioisomers of N-substituted azoles were obtained in high yields. In the experiment, the researchers used many compounds, for example, 7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6Quality Control of 7-Methyl-1H-benzo[d]imidazole).

7-Methyl-1H-benzo[d]imidazole (cas: 4887-83-6) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Quality Control of 7-Methyl-1H-benzo[d]imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Nitroimidazoles, part XXIII – activity of satranidazole series against anaerobic infections was written by Nagarajan, K.;Gowrishankar, R.;Arya, V. P.;George, T.;Nair, M. D.;Shenoy, S. J.;Sudarsanam, V.. And the article was included in Indian Journal of Experimental Biology in 1992.Recommanded Product: 3034-41-1 This article mentions the following:

A large number of nitroimidazoles were examined for in vitro activity against 3 anaerobes – Bacteroides fragilis (Bf), a strain of Bf resistant to metronidazole (I) and Clostridium perfringens and many found to be active. Among these may be mentioned 1-methyl-5-nitroimidazoles carrying N-bound heterocycles at position 2, such as satranidazole (II) and III (R¹ = H, R² = SO₂Et, SO₂NMe₂, morpholinylcarbonyl, morpholinoethylaminothioxomethyl) which are at least twice as active as I, ornidazole (IV) and tinidazole (V). Even more active are 5-nitroimidazolylbenzimidazole, -thiazolidinone, and -thiadiazolidine dioxide. Many other types of compounds derived from 1-methyl-2-amino-5-nitroimidazole are feebly active. Among 5-nitroimidazoles with a carbon substituent at position 2, I, IV and V are equiactive while dimetridazole is more active than I against Bf. Some 2-vinyl derivatives are very potent, with VI and VII being outstanding. Activity better than I is seen for nitroimidazooxazepines. 5-Nitroimidazoles are more active against anaerobes than the 4-nitro isomers. Antianaerobic and antiamoebic activities generally run parallel in these classes of compounds The study has led to the elaboration of the antianaerobic profile of II. In the experiment, the researchers used many compounds, for example, 1-Methyl-4-nitroimidazole (cas: 3034-41-1Recommanded Product: 3034-41-1).

1-Methyl-4-nitroimidazole (cas: 3034-41-1) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. This ring system is present in important biological building blocks, such as histidine and the related hormone histamine.Recommanded Product: 3034-41-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Predicting Toxicity of Ionic Liquids in Acetylcholinesterase Enzyme by the Quantitative Structure-Activity Relationship Method Using Topological Indexes was written by Yan, Fangyou;Xia, Shuqian;Wang, Qiang;Ma, Peisheng. And the article was included in Journal of Chemical & Engineering Data in 2012.HPLC of Formula: 79917-89-8 This article mentions the following:

A new topol. index (TI) was proposed based on atom characters (e.g., atom radius, atom electronegativity, etc.) and atom positions in the hydrogen-suppressed mol. structure in our previous work. In this work, the TI was used for predicting the toxicity of ILs in acetylcholin esterase (log EC₅₀ AChE) by the multiple linear regression (MLR) method. For ILs composed entirely of cations and anions, the TIs are calculated from cations and anions, resp. The 221 ILs used in the MLR model are based on imidazolium (Im), pyridinium (Pyi), pyrrolidinium (Pyo), ammonium (Am), phosphonium (Ph), quinolinium (Qu), piperidinium (Pi), and morpholinium (Mo). The regression coefficient (R²) and the overall average absolute error (AAE) are 0.877 and 0.153, resp. In the experiment, the researchers used many compounds, for example, 1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8HPLC of Formula: 79917-89-8).

1-Methyl-3-propylimidazolium Chloride (cas: 79917-89-8) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. HPLC of Formula: 79917-89-8

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis and biological study of acridine-based imidazolium salts was written by Sharhan, Olla;Heidelberg, Thorsten;Hashim, Najiahah Mohd;Salman, Abbas Abdulameer;Ali, Hapipah Mohd;Jayash, Soher Nagi. And the article was included in RSC Advances in 2018.Name: 1-Octyl-1H-imidazole This article mentions the following:

A new series of acridine based imidazolium salts was synthesized and evaluated for in vitro cytotoxicity against human cancer cell lines by an MTT assay. The synthesis applied a coupling of imidazoles with 9-chloroacridines, which originated from an Ullmann condensation of a 2-chloro-benzoic acid with an aniline. The target compounds were obtained in high yields. The DPPH assay indicated considerable antioxidant activity for target compounds with simple and short alkyl chains on the imidazole, while increasing chain length and the introduction of an addnl. ϖ-electron system in most cases reduced the activity. All compounds exhibited low biotoxicity against non-cancerous cell lines, whereas a few compounds showed promising anticancer activity. Unlike for the reference drugs Tamoxifen and Paclitaxel, the anticancer activity of acridine imidazolium ions is specific for only selected cancer types. Reasonable fluorescent behavior of the products provide potential for visualization of the distribution of active drugs in tissue. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Name: 1-Octyl-1H-imidazole).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. The solubility of imidazoles in ethers is lower than that in alcohols and decreases with increasing chain length of the ethers . In contrast, the solubility of benzimidazoles in alcohols (C3–C6) is higher than in water and generally decreases with a Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Name: 1-Octyl-1H-imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Study on properties of N,N’-dialkyl imidazole ionic liquid surfactant was written by Wang, Li-yan;Sun, Zhu;Yu, Ting-ting;Zhao, Bing;Li, Kuo. And the article was included in Yinran Zhuji in 2013.Electric Literature of C11H20N2 This article mentions the following:

Intermediates N-octyl imidazole was synthesized from imidazole and bromooctane. N,N’-dialkyl imidazole ionic liquid surfactants were synthesized from bromoalkanes (bromooctane, bromodecane, bromo-dodecane, bromotetradecane and bromohexadecane) and N-octyl imidazole under the assistance of ultrasound. The intermediate and target product were characterized by ¹H-NMR. The sterilization, surface tension, foaming properties and emulsifying properties of N,N’-dialkyl imidazole ionic liquid surfactants were determined The results showed that N,N’-dialkyl imidazole ionic liquid surfactants can inhibit the growth of Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Penicillium when the concentration of products were above 500 mg/L, and the greater the concentration, the better the anti-bactericidal performance. N,N’-dialkyl imidazole ionic liquid surfactants can reduce the surface tension of aqueous solution which reduced with the concentration increasing. With alkyl chain increasing, the foaming property and foam stability of N,N’-dialkyl imidazole ionic liquid surfactants increased first and then decreased. Using benzene as the oil phase, with alkyl chain increasing, the emulsifying ability of N,N’-dialkyl imidazole ionic liquid surfactants increased first and then decreased. In the experiment, the researchers used many compounds, for example, 1-Octyl-1H-imidazole (cas: 21252-69-7Electric Literature of C11H20N2).

1-Octyl-1H-imidazole (cas: 21252-69-7) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).Electric Literature of C11H20N2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthesis, proton NMR and electronic absorption spectra, and halochromic properties of bis(1,2-dimethyl-3-indolizinyl)hetarylmethane dyes was written by Naef, R.. And the article was included in Dyes and Pigments in 1983.COA of Formula: C9H8N2O This article mentions the following:

A series of bis(1,2-dimethyl-3-indolizinyl)hetarylmethane dyes (I) was synthesized, where the hetaryl substituents (R) are 2-benzoxazolyl, 2-benzothiazolyl, 1-methyl-2-benzimidazolyl, 4- and 2-pyridyl, and 4-quinolyl. The interpretations of the ¹H-NMR spectra supported the postulated structure of these dyes. The dependence of the electronic absorption spectra on the variation of the hetaryl substituents as well as on the pH^* conditions of the water-MeOH solvent mixture (halochromism) is discussed on the basis of PPP-CI and HMO calculations As with trihetarylmethane dyes described earlier (Naef, R., 1981), a second-order perturbational effect could be shown to make the main contribution to the bathochromic shift on substituting the chromophoric di-indolizinyl-monomethinecyanine fragment at the central C atom. This effect was superimposed on the general first-order perturbational shift induced by the increased out-of-plane rotation of the chromophore on substitution with the bulky hetarenes. Lower dissociation constants K^* and K^*_R⁺ in comparison with the di-indolylhetarylmethane series confirmed the calculated better delocalization of the pos. charge on the central C in the present system. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4COA of Formula: C9H8N2O).

1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.COA of Formula: C9H8N2O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Ribosidation of 4-amino-5-imidazolecarboxamide by Escherichia coli was written by Ben-Ishai, R.;Bergmann, Ernst D.;Volcani, B. E.. And the article was included in Nature (London, United Kingdom) in 1951.Related Products of 26832-08-6 This article mentions the following:

Evidence is presented for the conversion of 4-amino-5-imidazolecarboxamide (I) by E. coli into a glycoside. The supernatant from a cell suspension of E. coli B, incubated with the hydrochloride of I in 0.066 M phosphate buffer, contained a growth-enhancing component for a purine-requiring E. coli mutant, which was more effective than I. The supernatant was lyophilized, concentrated, chromatographed on paper with 5% KH₂PO₄ in iso-AmOH, and developed by diazotization. Two distinct spots were obtained; R_f for the unknown was 0.63, and for the HCl of I 0.68. A pos. orcinol test and a color reaction with diphenylamine, exceeding that for the blank, indicated the presence of desoxyribose. The ultraviolet spectrum for the unknown had an absorption maximum at 2600 A. The ultraviolet maximum for the hydrochloride of I was 2680 A. In the experiment, the researchers used many compounds, for example, 1H-Imidazole-4-carboxamide (cas: 26832-08-6Related Products of 26832-08-6).

1H-Imidazole-4-carboxamide (cas: 26832-08-6) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Related Products of 26832-08-6

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

A New Class of Singlet Carbene Ligands was written by Alcarazo, Manuel;Suarez, Rosa M.;Goddard, Richard;Fuerstner, Alois. And the article was included in Chemistry – A European Journal in 2010.Product Details of 3012-80-4 This article mentions the following:

The synthesis of a series of singlet carbene ligands based on vinyl phosphonium (I; R = Ph, 2-pyridylphenyl, cyclohexyl, dimethylamino) and benzimidazolium salts (II) are reported. Deprotonation with potassium hexamethyldisilazide (KHMDS) yields a resonance form which can be described as a push-pull cumulene or as a zwitterionic form. The corresponding gold and rhodium complexes were obtained through treatment I or II with KHMDS at -78° followed by addition of (Me₂S)AuCl, [Rh(CO)₂Cl]₂ or [Rh(COD)Cl]₂ (COD = η⁴-1,5-cyclooctadiene). Representative examples of the new complexes were determined by x-ray crystallog. Both I and II are readily accessible precursors for a new class of singlet carbene ligands having appreciable donor qualities equal to or greater than those of traditional N-heterocyclic carbenes. In the experiment, the researchers used many compounds, for example, 1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4Product Details of 3012-80-4).

1-Methyl-1H-benzo[d]imidazole-2-carbaldehyde (cas: 3012-80-4) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.Product Details of 3012-80-4

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Preparation of imidazole and imidazolium 2-carbaldehydes was written by Ricciardi, Fiore;Joullie, Madeleine M.. And the article was included in Organic Preparations and Procedures International in 1983.Recommanded Product: 85692-37-1 This article mentions the following:

1,3-Dimethylimidazolium iodide (I) was converted to acylation products II (R = Me, H). Thus, HCO₂Et was added to I and K₂CO₃ in Me₂CO, and the mixture was stirred overnight to give II (R = H). II were heated with Me₃SiI in sulfolane to give bases III. In the experiment, the researchers used many compounds, for example, 1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1Recommanded Product: 85692-37-1).

1-(1-Methyl-1H-imidazol-2-yl)ethanone (cas: 85692-37-1) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Recommanded Product: 85692-37-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem