ESR and polarography of nitro azoles. 4. Polarographic study of nitrobenzimidazoles was written by Lopyrev, V. A.;Larina, L. I.;Baumane, L.;Shibanova, E. F.;Gavars, R.;Ponomareva, S. M.;Vakul’skaya, T. I.;Stradins, J.. And the article was included in Khimiya Geterotsiklicheskikh Soedinenii in 1984.Product Details of 93521-65-4 The following contents are mentioned in the article:
The 1st and 2nd polarog. half-wave potentials (E) of benzimidazoles I (R = NMe2, NH2, OMe, OEt, Me, H, Cl, etc.) were subjected to correlation anal. The effect of R on the 1st E values was exerted via the inductive and resonance mechanisms to approx. equal degrees; the effect of R on the 2nd E values was exerted primarily via the resonance mechanism. The calculation of a radical-stabilizing factor was discussed. The pK2 values of I in MeCN range from 16.63 for I (R = cyano) to 23.40 for I (R = Me). This study involved multiple reactions and reactants, such as Methyl 5-Nitro-1H-benzimidazole-2-carboxylate (cas: 93521-65-4Product Details of 93521-65-4).
Methyl 5-Nitro-1H-benzimidazole-2-carboxylate (cas: 93521-65-4) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Product Details of 93521-65-4
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem