Category: 934-32-7

《Amino-functional ZIF-8 nanocrystals by microemulsion based mixed linker strategy and the enhanced CO2/N2 separation》 was published in Separation and Purification Technology in 2020. These research results belong to Ding, Rui; Zheng, Wenji; Yang, Kai; Dai, Yan; Ruan, Xuehua; Yan, Xiaoming; He, Gaohong. Electric Literature of C7H7N3 The article mentions the following:

High permeability and selectivity are desirable for mixed matrix membranes (MMMs) based CO2 separation Herein, a microemulsion based mixed linker strategy is proposed to introduce amino groups during the growth of ZIF-8. Compared to post-synthetic modification, this method presents a less reduction in SBET of ZIF-8, which is beneficial for CO2 adsorption. By controlling the ratio of 2-methylimidazole to 2-aminobenzimidazole, NH2-ZIF-8 with various morphologies and sizes were synthesized and serve as the filler to fabricate the MMMs for CO2 capture. From the SEM, no obvious agglomerations or defects are observed in ZIF-8/Pebax MMMs, due to the amino groups in ZIF-8 can interact with the amide in Pebax chain, which can improve compatibility between ZIF-8 and Pebax. With the amino groups, NH2-ZIF-8 shows higher affinity with CO2 than that of non-amine-functionalized ZIF-8, leading to an enhancement in the separation performances. When the MMM doped with 6 weight% of NH2-ZIF-8(10), the CO2 permeability reaches up to 163.8 Barrer, which increases by around 53% and 107.6% in contrast with the ZIF-8/Pebax MMM and pure Pebax membrane. Besides, the CO2/N2 selectivity is enhanced by around 10% and 27%, resp. These results indicate that amine-functional modification by mixed ligands is a useful way to construct MOFs-based MMMs with high performance for CO2/N2 separation The experimental part of the paper was very detailed, including the reaction process of 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Electric Literature of C7H7N3)

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Electric Literature of C7H7N3

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In 2019,Journal of Saudi Chemical Society included an article by Karimi, Maryam; Naimi-Jamal, M. R.. Application In Synthesis of 1H-Benzo[d]imidazol-2-amine. The article was titled 《Carboxymethyl cellulose as a green and biodegradable catalyst for the solvent-free synthesis of benzimidazoloquinazolinone derivatives》. The information in the text is summarized as follows:

CM-cellulose (CMC) was used as an efficient, and environmentally friendly catalyst for the solvent-free three-component synthesis of quinazolinone derivatives by condensation of 2-aminobenzimidazole, dimedone or 1,3-cyclohexanedione, and different aldehydes. The catalyst was recovered easily, and reused without significant loss of its activity. Solvent-free and mild reaction conditions, nontoxic-, biodegradable-, and inexpensive catalyst, environmentally benign method, and high to excellent yields are some important features of this protocol. In addition to this study using 1H-Benzo[d]imidazol-2-amine, there are many other studies that have used 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Application In Synthesis of 1H-Benzo[d]imidazol-2-amine) was used in this study.

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Application In Synthesis of 1H-Benzo[d]imidazol-2-amine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《Controlled Synthesis of Co@N-Doped Carbon by Pyrolysis of ZIF with 2-Aminobenzimidazole Ligand for Enhancing Oxygen Reduction Reaction and the Application in Zn-Air Battery》 was published in ACS Applied Materials & Interfaces in 2020. These research results belong to Zhang, Minghui; Zhang, Erhuan; Hu, Chunyan; Zhao, Yong; Zhang, Han-ming; Zhang, Yijie; Ji, Muwei; Yu, Jiali; Cong, Guangtao; Liu, Huichao; Zhang, Jiatao; Zhu, Caizhen; Xu, Jian. Category: imidazoles-derivatives The article mentions the following:

The Co/N-doped carbon material, as an important electrocatalytic material, has been attracted intense interest in ORR and Zn-air battery. Here, we report an efficient Co@N-doped carbon catalyst (Co@N-C-1) obtained by pyrolysis of ZIF precursor with 2-aminobenzimidazole. The introduction of 2-aminobenzimidazole results in the formation of hierarchical meso/microporous structure of the as-prepared Co@N-C-1, effectively avoiding the aggregation of Co nanoparticles during pyrolysis and the higher N content, which contributes to enhance the ORR electrocatalytic activities. The obtained Co@N-C-1 exhibits remarkable ORR performance with a half-wave potential of 0.938 V vs RHE in alk. media. As the air catalyst of zinc-air batteries, Co@N-C-1 displays 1.439 V of open-circuit voltage and 1413.3 Wh·kg-1 of energy d. In the part of experimental materials, we found many familiar compounds, such as 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Category: imidazoles-derivatives)

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《A novel 2-aminobenzimidazole-based compound Jzu 17 exhibits anti-angiogenesis effects by targeting VEGFR-2 signalling》 was written by Lien, Jin-Cherng; Chung, Chi-Li; Huang, Tur-Fu; Chang, Tsung-Chia; Chen, Kuan-Chung; Gao, Ging-Yan; Hsu, Ming-Jen; Huang, Shiu-Wen. Reference of 1H-Benzo[d]imidazol-2-amineThis research focused onumbilical vein endothelial cell 2 aminobenzimidazole Jzu 17 antiangiogenesis. The article conveys some information:

In this study, we aim to characterize the anti-angiogenic mechanisms of a novel 2-aminobenzimidazole-based compound, Jzu 17, in an effort to develop novel angiogenesis inhibitor. Exptl. Approach : Effects of Jzu 17 on endothelial cell proliferation, migration, invasion, and activation of signalling mols. induced by VEGF-A, were analyzed by immunoblotting, MTT, BrdU, migration, and invasion assays. We performed tube formation assay, aorta ring sprouting assay, matrigel plug assay, and a mouse model of metastasis to evaluate ex vivo and in vivo anti-angiogenic effects of Jzu 17. Key Results : Jzu 17 inhibited VEGF-A-induced cell proliferation, migration, invasion, and endothelial tube formation of HUVECs. Jzu 17 suppressed VEGF-A-induced microvessel sprouting ex vivo and attenuated VEGF-A- or tumor cell-induced neovascularization in vivo. Jzu 17 also reduced B16F10 melanoma lung metastasis. In addition, Jzu 17 inhibited the phosphorylation of VEGFR-2 and its downstream signalling mols. in VEGF-A-stimulated HUVECs. Results from computer modeling further showed that Jzu 17 binds to VEGFR-2 with high affinity. Conclusions and Implications : Jzu 17 may inhibit endothelial remodelling and suppress angiogenesis through targeting VEGF-A-VEGFR-2 signalling. These results also suggest Jzu 17 as a potential lead compound and warrant the clin. development of similar agents in the treatment of cancer and angiogenesis-related diseases.1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Reference of 1H-Benzo[d]imidazol-2-amine) was used in this study.

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Reference of 1H-Benzo[d]imidazol-2-amine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Prasoona, G.; Kishore, B.; Brahmeshwari, G. published their research in Russian Journal of Organic Chemistry in 2021. The article was titled 《A Simple and Efficient Four-Component One-Pot Synthesis of Novel 2-Aryl-3-benzimidazolyl-3,4-dihydroimidazo[4,5-b]indoles Catalyzed by Ceric Ammonium Nitrate in Aqueous Ethanol》.Reference of 1H-Benzo[d]imidazol-2-amine The article contains the following contents:

A simple and efficient protocol for the synthesis of benzimidazolylimidazo[4,5-b]indoles was developed through the condensation of 2-aminobenzimidazoles, aromatic aldehydes, ammonium acetate and isatins via multicomponent reaction strategy using ceric ammonium nitrate as catalyst. The key advantages of the four-component reaction were easy work-up, high yield, short reaction time and environmentally safe solvent. After reading the article, we found that the author used 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Reference of 1H-Benzo[d]imidazol-2-amine)

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Reference of 1H-Benzo[d]imidazol-2-amine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In 2022,Machado, R. M.; da Silva, S. W.; Bernardes, A. M.; Ferreira, J. Z. published an article in Journal of Environmental Management. The title of the article was 《Degradation of carbendazim in aqueous solution by different settings of photochemical and electrochemical oxidation processes》.Quality Control of 1H-Benzo[d]imidazol-2-amine The author mentioned the following in the article:

The present study analyzed the performance of photochem. and electrochem. techniques in the degradation and mineralization of the pesticide carbendazim (CBZ). Direct photolysis (DP), heterogeneous photocatalysis (HP), photoelectrocatalysis (PEC), and electrochem. oxidation (EO) were tested, and the influence of UV radiation, c.d. (j), and supporting electrolyte concentration were evaluated. The results suggest that CBZ is only degraded by DP when UV-C254nm is used. For HP, the CBZ degradation was observed both when UV-A365nm or UV-C254nm were used, which is related to the reactive oxygen species (ROS) formed by the photocatalytic activity (photon-ROS). Neither DP nor HP were able to mineralize CBZ, demonstrating its resistance to photomediated processes. For EO, regardless of the j, there were higher CBZ degradation and mineralization than those observed when using DP and HP. The increase in the supporting electrolyte concentration (Na2SO4) did not affect the levels of degradation and mineralization of CBZ. Concerning the PEC, a CBZ mineralization of 52.2% was accomplished. These findings demonstrate that the EO is the main pathway for CBZ mineralization, suggesting an addnl. effect of the electro-ROS on the photon-ROS and UV-C254nm. The values of mineralization, kinetics, and half-life show that PEC UV-C254nm with a j of 15 mA cm-2 was the best setting for the degradation and mineralization of CBZ. However, when the values of specific energy consumption were considered for industrial applications, the use of EO with a j of 3 mA cm-2 and 4 g L-1 of Na2SO2 becomes more attractive. The assessment of byproducts formed after this best cost-efficient treatment setting revealed the presence of aromatic and aliphatic compounds from CBZ degradation Acute phytotoxicity results showed that the presence of sodium sulfate can be a representative factor regarding the toxicity of samples treated in electrochem. systems. The experimental part of the paper was very detailed, including the reaction process of 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Quality Control of 1H-Benzo[d]imidazol-2-amine)

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Quality Control of 1H-Benzo[d]imidazol-2-amine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The author of 《Synthesis of Imidazolium and Benzimidazolium Triiodides》 were Shagun, L. G.; Dorofeev, I. A.; Zhilitskaya, L. V.; Yarosh, N. O.; Larina, L. I.. And the article was published in Russian Journal of Organic Chemistry in 2019. Name: 1H-Benzo[d]imidazol-2-amine The author mentioned the following in the article:

1,3-(Di)acetonylimidazolium and -benzimidazolium triiodides were synthesized in a one-pot fashion by reactions of imidazole, 3-(1H-imidazol-4-yl)prop-2-enoic acid, benzimidazole, benzimidazol-2-amine, and 2-ethylbenzimidazole with 1-iodopropan-2-one and mol. iodine under solvent-free conditions in the absence of a base and catalyst at room temperature The reaction of 1H-benzimidazole-2-thiol with 1-iodopropan-2-one and iodine afforded 2-(2-oxopropylsulfanyl)imidazolium triiodide. The reaction direction and yield did not change when 2-iodo-1-(thiophen-2-yl)ethanone was used instead of 1-iodopropan-2-one. After reading the article, we found that the author used 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Name: 1H-Benzo[d]imidazol-2-amine)

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Name: 1H-Benzo[d]imidazol-2-amine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In 2022,Saeedian Moghadam, Ebrahim; Al-Saadi, Abdullah Mohammed; Talebi, Meysam; Amanlou, Massoud; Amini, Mohsen; Abdel-Jalil, Raid published an article in Synthetic Communications. The title of the article was 《Design, synthesis, and bioactivity investigation of novel benzimidazole derivatives as potent urease inhibitors》.Product Details of 934-32-7 The author mentioned the following in the article:

Herein, we synthesized a series of novel benzimidazole derivatives and screened their bioactivity as potent urease inhibitors. The structure of the was elucidated using spectroscopic technics (1H-NMR, 13C-NMR, MS), elemental anal., and m.p. The urease inhibition activity was evaluated using the urease enzyme inhibition kit. All , except , showed higher urease inhibition activity (0.77 to 6.25 μM) in comparison to thiourea and hydroxyurea as standard (IC50: 22 and 100 μM resp.). and exhibited the best activity with the IC50 value of 0.77 and 1.26 μM resp. A mol. docking study showed the mode of interactions between the most active compound and enzyme active site. To investigate the cytotoxicity profile of the target compounds, an MTT assay was done on two different cell lines which showed all have IC50 values higher than 50 μM on both tested cell lines.1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Product Details of 934-32-7) was used in this study.

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Product Details of 934-32-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In 2019,Colloids and Surfaces, B: Biointerfaces included an article by Tan, Yulong; Leonhard, Matthias; Moser, Doris; Ma, Su; Schneider-Stickler, Berit. Recommanded Product: 934-32-7. The article was titled 《Antibiofilm efficacy of curcumin in combination with 2-aminobenzimidazole against single- and mixed-species biofilms of Candida albicans and Staphylococcus aureus》. The information in the text is summarized as follows:

Mixed fungal and bacterial biofilm associated infections of implants have been a huge challenge in health care because of the increased resistance to antimicrobials and the critical biol. differences between fungi and bacteria. In this study, we evaluated the 2-aminobenzimidazole (2ABI) and curcumin (CUR) alone to inhibit planktonic cell growth, adhesion as well as single and mixed species biofilms of Candida albicans and Staphylococcus aureus on silicone. The combined effects between 2ABI and CUR on mixed species biofilm formation and pre-formed biofilm were assessed. Our work showed that 2ABI or CUR alone was effective as a sole agent, inhibiting planktonic growth, adhesion and the biofilm formation of bacteria and fungi on the silicone surface. The combination of 2ABI and CUR exhibited the enhanced effect on mixed biofilm compared to mono-drug therapy. The biofilm architecture was investigated by SEM (SEM) and the distinction of living/dead organisms within biofilm was examined by confocal laser scanning microscopy (CLSM). The combination activity was most potent on mixed biofilm. These results suggest the potential applicability of 2ABI and CUR to treatment of biofilm related device infections. The results came from multiple reactions, including the reaction of 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7Recommanded Product: 934-32-7)

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.Recommanded Product: 934-32-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

《ZIF-8 Membrane Separation Performance Tuning by Vapor Phase Ligand Treatment》 was written by Eum, Kiwon; Hayashi, Mikio; De Mello, Matheus Dorneles; Xue, Feng; Kwon, Hyuk Taek; Tsapatsis, Michael. HPLC of Formula: 934-32-7This research focused onZIF membrane separation vapor phase ligand treatment; ZIF-8; ligand-induced permselectivity; membranes; metal-organic frameworks; vapor phase. The article conveys some information:

Vapor phase ligand treatment (VPLT) of 2-aminobenzimidazole (2abIm) for 2-methylimidazole (2mIm) in ZIF-8 membranes prepared by two different methods (LIPS: ligand induced permselectivation and RTD: rapid thermal deposition) results in a notable shift of the mol. level cut-off to smaller mols. establishing selectivity improvements from ca. 1.8 to 5 for O2/N2; 2.2 to 32 for CO2/CH4; 2.4 to 24 for CO2/N2; 4.8 to 140 for H2/CH4 and 5.2 to 126 for H2/N2. Stable (based on a one-week test) oxygen-selective air separation performance at ambient temperature, 7 bar(a) feed, and 1 bar(a) sweep-free permeate with a mixture separation factor of 4.5 and oxygen flux of 2.6×10-3 mol m-2 s-1 is established. LIPS and RTD membranes exhibit fast and gradual evolution upon a 2abIm-VPLT, resp., reflecting differences in their thickness and microstructure. Functional reversibility is demonstrated by showing that the original permeation properties of the VPLT-LIPS membranes can be recovered upon 2mIm-VPLT. In the experiment, the researchers used many compounds, for example, 1H-Benzo[d]imidazol-2-amine(cas: 934-32-7HPLC of Formula: 934-32-7)

1H-Benzo[d]imidazol-2-amine(cas: 934-32-7) can be used in the hydrolysis of a choline carbonate. It was also used in the synthesis of imidazo[1,2-a]benzimidazoles.HPLC of Formula: 934-32-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem