Transition-metal-free regioselective C-H halogenation of imidazo[1,2-a]pyridines: sodium chlorite/bromite as the halogen source was written by Li, Junxuan;Tang, Jiayi;Wu, Yuanheng;He, Qiuxing;Yu, Yue. And the article was included in RSC Advances in 2018.SDS of cas: 866135-66-2 The following contents are mentioned in the article:
A facile transition-metal-free regioselective halogenation of imidazo[1,2-a]pyridines using sodium chlorite/bromite as the halogen source is presented. The reaction has provided an efficient method for the formation of C-Cl or C-Br bonds to synthesize 3-chloro or 3-bromo-imidazo[1,2-a]pyridines which were then efficiently transformed into imidazo[1,2-a]pyridine core π-systems by Suzuki-Miyaura reactions. This study involved multiple reactions and reactants, such as 3-Bromo-8-methylimidazo[1,2-a]pyridine (cas: 866135-66-2SDS of cas: 866135-66-2).
3-Bromo-8-methylimidazo[1,2-a]pyridine (cas: 866135-66-2) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole has been usedin the lysis, wash and elution buffer for the purification of histidine tagged Sonic Hedgehog(shh-N) protein, in elution buffer in stepwise gradient for the purification of histidine tagged aldo keto reductases using nickel affinity chromatography, as a component of homogenization buffer for the purification of phagosomal compartments from dendritic cells.SDS of cas: 866135-66-2
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem