Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 7164-98-9, name is 1-Phenyl-1H-imidazole, This compound has unique chemical properties. The synthetic route is as follows., name: 1-Phenyl-1H-imidazole
General procedure: Under nitrogen atmosphere, to the solution of 1,3-di-imidazolylbenzene (2.0126 g, 10 mmol) in dry THF (150 mL) cooled to ?78Cwas added dropwise with N, N, N, N-tetramethylethylenediamine(TMEDA, 3.0 mL, 20 mmol) and n-BuLi (2.5 M in hexane, 8.8 mL,22 mmol). The obtained mixture after stirring vigorously for 1 h,chlorodiphenylphosphine (PPh2Cl, 4.953 g, 22 mmol) was addeddropwise. The resultant mixture was stirred overnight with thereaction temperature increasing to ambient. After quenchingexcess n-BuLi with deionized water, the obtained oily mixture wasremoved of solvent in vacuo. The residue was purified by columnchromatography on silica gel, using CH2Cl2/ethyl acetate (30:1)as an eluent, to yield L1 as a white solid (2.53 g, 44percent).1H NMR(400 MHz, , ppm, CD3CN): = 7.47 (t, J = 8 Hz, 1H, HPh), 7.32?7.36(m, 24H, HPh + imi), 7.26 (s, 2H, Himi), 7.18 (s, 1H, HPh).31P NMR(162 MHz, , ppm, CDCl3): = ?28.2 (s, PPh2). The31P NMR signalof L1 ( = ?28.2 ppm) observed herein was consistent to the onereported by Chauvin [24] with two phosphine fragments located intrans-position but different to the one reported by us [30] with twophosphine fragments located in cis-position.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 7164-98-9.
Reference:
Article; Zhang, Heng; Li, Yong-Qi; Wang, Peng; Lu, Yong; Zhao, Xiao-Li; Liu, Ye; Journal of Molecular Catalysis A: Chemical; vol. 411; (2016); p. 337 – 343;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem