Teulade, J. C.’s team published research in Australian Journal of Chemistry in 1982 | CAS: 67625-38-1

Australian Journal of Chemistry published new progress about Bond order. 67625-38-1 belongs to class imidazoles-derivatives, name is Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate, and the molecular formula is C10H9ClN2O2, Recommanded Product: Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate.

Teulade, J. C. published the artcileNew aspects of the nitration of some imidazo[1,2-a]pyridines. CNDO/2 calculations from x-ray structures, Recommanded Product: Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate, the main research area is nitration regiochem imidazopyridine derivative; crystal structure imidazopyridine derivative; mol structure imidazopyridine derivative; MO imidazopyridine derivative.

The reactivity of the imidazo[1,2-a]pyridine system was examined CNDO/2 calculations based on x-ray structure determinations of 5-ethoxyimidazo[1,2-a]pyridine, Et 8-methylimidazo[1,2-a]pyridine-2-carboxylate, and Et 6-methyl-3-nitroimidazo[1,2-a]pyridine-2-carboxylate are compared with exptl. results of the nitration of variously substituted imidazo[1,2-a]pyridines, and are found compatible with the individual reactivities.

Australian Journal of Chemistry published new progress about Bond order. 67625-38-1 belongs to class imidazoles-derivatives, name is Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate, and the molecular formula is C10H9ClN2O2, Recommanded Product: Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Feng, Song’s team published research in ACS Medicinal Chemistry Letters in 2015-03-12 | CAS: 67625-38-1

ACS Medicinal Chemistry Letters published new progress about Antiviral agents. 67625-38-1 belongs to class imidazoles-derivatives, name is Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate, and the molecular formula is C10H9ClN2O2, Synthetic Route of 67625-38-1.

Feng, Song published the artcileDiscovery of Imidazopyridine Derivatives as Highly Potent Respiratory Syncytial Virus Fusion Inhibitors, Synthetic Route of 67625-38-1, the main research area is imidazopyridine preparation antiviral respiratory syncytial virus fusion inhibitory activity; Respiratory syncytial virus (RSV); antiviral; fusion inhibitors; heterocycle; imidazopyridine; virus.

A series of imidazolepyridine derivatives were designed and synthesized according to the established docking studies. The imidazopyridine derivatives were found to have good potency and phys.-chem. properties. Several highly potent compounds such as I (R = CONH2, SO2Me, SO2Et) were identified with single nanomolar activities. The most potent compound I (R = SO2Et) showed an IC50 of 3 nM, lower microsome clearance and no CYP inhibition. The profile of I (R = SO2Et) appeared to be superior to BMS433771, and supported further optimization.

ACS Medicinal Chemistry Letters published new progress about Antiviral agents. 67625-38-1 belongs to class imidazoles-derivatives, name is Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate, and the molecular formula is C10H9ClN2O2, Synthetic Route of 67625-38-1.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Joshi-Pangu, Amruta’s team published research in Journal of Organic Chemistry in 2016-04-15 | CAS: 67625-38-1

Journal of Organic Chemistry published new progress about Cyclopropanation catalysts, stereoselective. 67625-38-1 belongs to class imidazoles-derivatives, name is Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate, and the molecular formula is C10H9ClN2O2, Application In Synthesis of 67625-38-1.

Joshi-Pangu, Amruta published the artcileDearomatization of Electron-Deficient Nitrogen Heterocycles via Cobalt-Catalyzed Asymmetric Cyclopropanation, Application In Synthesis of 67625-38-1, the main research area is dearomatization electron deficient nitrogen heterocycle cobalt catalyst stereoselective cyclopropanation.

The dearomatization of a series of electron-deficient nitrogen heterocycles has been achieved through a cobalt-catalyzed asym. cyclopropanation reaction. This reaction proceeds with high levels of enantio- and diastereoselectivity to afford unique cyclopropanes that can be further functionalized to provide complex heterocyclic building blocks.

Journal of Organic Chemistry published new progress about Cyclopropanation catalysts, stereoselective. 67625-38-1 belongs to class imidazoles-derivatives, name is Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate, and the molecular formula is C10H9ClN2O2, Application In Synthesis of 67625-38-1.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Wu, Feng’s team published research in Russian Journal of General Chemistry in 2022-07-31 | CAS: 67625-38-1

Russian Journal of General Chemistry published new progress about Aminopyridines Role: RCT (Reactant), RACT (Reactant or Reagent). 67625-38-1 belongs to class imidazoles-derivatives, name is Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate, and the molecular formula is C10H9ClN2O2, Safety of Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate.

Wu, Feng published the artcileElectrophilic Fluorination of Imidazoheterocycles by Selectfluor, Safety of Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate, the main research area is fluoro imidazoheterocycle preparation; imidazoheterocycle preparation electrophilic fluorination; ethyl bromopyruvate pyridinamine cyclization.

Response surface anal. (RSA) has been used for optimization of the synthesis using selectfluor as a fluorine source and Et imidazo[1,2-a]pyridine-2-carboxylate as a substrate. The latter has been synthesized by cyclization of Me 2-aminopyridine-3-formate with Et bromopyruvate. The optimal reaction conditions have been determined to be as follows: time 3 h, temperature 30°C and selectfluor rate 2.3 equivalent The triplicated verification experiments have led to the average yield of 87%. Four other fluorides of imidazoheterocycles I (R = H, Br; R1 = H, CHO, C(O)OMe; R2 = H, Me, Cl, F; R3 = H, ethoxycarbonyl; X = N, CH) have been synthesized under the optimized conditions.

Russian Journal of General Chemistry published new progress about Aminopyridines Role: RCT (Reactant), RACT (Reactant or Reagent). 67625-38-1 belongs to class imidazoles-derivatives, name is Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate, and the molecular formula is C10H9ClN2O2, Safety of Ethyl 6-chloroimidazo[1,2-a]pyridine-2-carboxylate.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem