Sources of common compounds: 2-Amino-1H-benzo[d]imidazole-5-carbonitrile

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-Amino-1H-benzo[d]imidazole-5-carbonitrile, its application will become more common.

Electric Literature of 63655-40-3,Some common heterocyclic compound, 63655-40-3, name is 2-Amino-1H-benzo[d]imidazole-5-carbonitrile, molecular formula is C8H6N4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Benzimidazole based Schiff base 1 is prepared from 2-aminobenzimidazoleand aromatic aldehyde in absolute ethanolfor 12 h at reflux, as reported previously (17). Detailed description can be found in the Supporting Information.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-Amino-1H-benzo[d]imidazole-5-carbonitrile, its application will become more common.

Reference:
Article; Horak, Ema; Vianello, Robert; Hranjec, Marijana; Murkovi? Steinberg, Ivana; Supramolecular Chemistry; vol. 30; 10; (2018); p. 891 – 900;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Sources of common compounds: 63655-40-3

The synthetic route of 2-Amino-1H-benzo[d]imidazole-5-carbonitrile has been constantly updated, and we look forward to future research findings.

Related Products of 63655-40-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 63655-40-3, name is 2-Amino-1H-benzo[d]imidazole-5-carbonitrile belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.

General procedure: To a solution of corresponding benzoyl chlorides 2-3 in drytoluene, a solution of 2-amino-5(6)-cyanobenzimidazole 29in dry toluene was added dropwise, followed by the additionof Et3N. The reaction mixture was refluxed for severalhours. After cooling the solution was concentrated and theobtained solid was filtered off and recrystallized fromappropriate solvent.

The synthetic route of 2-Amino-1H-benzo[d]imidazole-5-carbonitrile has been constantly updated, and we look forward to future research findings.

Reference:
Article; Cindri?, Maja; Sovi?, Irena; Martin-Kleiner, Irena; Kralj, Marijeta; Ma?ek, Tomislav; Hranjec, Marijana; Star?evi?, Kristina; Medicinal Chemistry Research; vol. 26; 9; (2017); p. 2024 – 2037;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem