Category: 5805-39-0

Bairy, Gurupada;Dey, Arka;Dutta, Basudeb;Ray, Partha Pratim;Sinha, Chittaranjan published 《2D Cd(II)-MOF of Pyridyl-Imidazoquinazoline: Structure, Luminescence, and Selective Detection of TNP and Fabrication of Semiconducting Devices》. The research results were published in《Crystal Growth & Design》 in 2022.Formula: C13H11N3 The article conveys some information:

Pyridyl-substituted imidazoquinolines are highly fluorescent probes and are useful for the design of smart materials. A hitherto unknown pyridyl-imidazoquinazoline-coordinated two-dimensional (2D)-Cd(II)-MOF {[Cd₂(5-nip)₂(pdiq)₂(H₂O)₂(CH₃OH)]·H₂O}_n (CP 1), [H₂nip = 5-nitroisophthalic acid and pdiq = 6-(pyridin-4-yl)-5,6-dihydrobenzo[4,5]imidazo[1,2-c]quinazoline] was designed and structurally confirmed by single-crystal x-ray crystallog. The presence of C-H···π and π···π interactions in CP 1 makes it a three-dimensional (3D) supramol. structure. The excellent luminescent behavior of CP 1 is selectively quenched by trinitrophenol (TNP) even in the presence of potentially intrusive nitroarom. explosives (NAEs). A limit of detection (LOD) of 2.75 x 10^-7 M for TNP is achieved (3σ/m). In addition, the CP 1 displays elec. conductivity on an electronic device with the metal-semiconductor (MS) junction. Current vs. voltage (I-v plot) correlation reveals the substantial enhancement of elec. conductivity upon illumination (Λ: 1.12 x 10^-3 S m^-1 (dark), 6.33 x 10^-3 S m^-1 (light)) along with a decrease in energy barrier (Φ_B: 0.53 (dark), 0.42 (light)). The plots of log Vvs. log i show a non-ohmic feature at a higher voltage (log V ≥ 0) both in the dark and the light phase, which is the characteristic of a Schottky diode barrier (SDB).2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) were involved in the experimental procedure.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Formula: C13H11N3) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Yin, Zhi-Yuan;Hu, Jing-Han;Gui, Kai;Fu, Qing-Qing;Yao, Ying;Zhou, Fu-Long;Ma, Li-Long;Zhang, Zhi-Peng published 《AIE based colorimetric and “turn-on” fluorescence Schiff base sensor for detecting Fe³⁺ in an aqueous media and its application》 in 2020. The article was appeared in 《Journal of Photochemistry and Photobiology, A: Chemistry》. They have made some progress in their research.Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline The article mentions the following:

A novel AIE active dual-channel coumarin derivatives, chemosensor G1, was synthesized and used for detecting Fe³⁺ (in water solution) in DMSO/H₂O (1:9, volume/volume, pH = 7.2) binary solutions, which induced the color of solution of G1 from yellow to shallow orange and increased the fluorescence emission, indicating that G1 could act as a corking colorimetric and “turn-on” fluorescence probe for detecting Fe³⁺. What′s more, sensor G1 has good anti-interference toward Ca²⁺, Hg²⁺, Cu²⁺, Ag⁺, Cd²⁺, Co²⁺, Ni²⁺, Mg²⁺, Pb²⁺, Zn²⁺ and Cr³⁺. Notably, the actual usage of sensor G1 was further demonstrated by logic gates and test kits. And 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) was used in the research process.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Name: 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Martinez-Ariza, Guillermo;McConnell, Nicholas;Hulme, Christopher published 《One-Pot Two-Step Multicomponent Process of Indole and Other Nitrogenous Heterocycles or Amines toward α-Oxo-acetamidines》. The research results were published in《Organic Letters》 in 2016.SDS of cas: 5805-39-0 The article conveys some information:

A cesium carbonate promoted three-component reaction of N-H containing heterocycles, primary or secondary amines, arylglyoxaldehydes, and anilines is reported. The key step involves a tandem sequence of N-1 addition of a heterocycle or an amine to preformed α-iminoketones, followed by an air- or oxygen-mediated oxidation to form α-oxo acetamidines. The scope of the reaction is broad, and this novel methodol. is applied toward the synthesis of various polycyclic heterocycles. To complete the study, the researchers used 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 SDS of cas: 5805-39-0) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Electric Literature of C13H11N3《A novel pyrazole bearing imidazole frame as ratiometric fluorescent chemosensor for Al³⁺/Fe³⁺ ions and its application in HeLa cell imaging》 was published in 2020. The authors were Ganesan, Jeya Shree;Sepperumal, Murugesan;Balasubramaniem, Ashokkumar;Ayyanar, Siva, and the article was included in《Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy》. The author mentioned the following in the article:

New pyrazole bearing imidazole derivative was successfully synthesized and thoroughly characterized by various spectroanal. techniques. The sensor DIBI shows a highly selective and sensitive fluorescent response with the addition of Al³⁺/Fe³⁺ ions in acetonitrile-water mixture The strong fluorescent mol. exhibits a notable ratiometric emissions at 462 nm and 470 nm for Al³⁺ and Fe³⁺ ions, resp. (λ_ex = 280 nm). Job’s plot studies conclude that the coordination between DIBI with Al³⁺/Fe³⁺ was 1:1 binding stoichiometry. The limit of detection of DIBI with Al³⁺/Fe³⁺ was calculated as 2.12 × 10^-7 M and 1.73 × 10^-6 M, resp. The TD-DFT calculations further supported the photonics performances of the free probe and its complexes. The reversibility and reusability of the sensor mol. were studied using EDTA. The probe was used to track Al³⁺/Fe³⁺ in cancer cells via fluorescence microscopy. The experimental procedure involved many compounds, such as 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Electric Literature of C13H11N3) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Recommanded Product: 2-(1H-Benzo[d]imidazol-2-yl)aniline《Novel ion imprinted polymer electrochemical sensor for the selective detection of lead(II)》 was published in 2020. The authors were Dahaghin, Zohreh;Kilmartin, Paul A.;Mousavi, Hassan Zavvar, and the article was included in《Food Chemistry》. The author mentioned the following in the article:

The application of a novel Pb²⁺ selective sensor based on the ionic imprinted polymer in determining trace levels of lead in natural water and in fruit juice was investigated using differential pulse voltammetry (DPV). The new and selective magnetic ion-imprinted polymer (Fe₃O₄@SiO₂@IIP) was synthesized using 2-(2-aminophenyl)-1H-benzimidazole and 4-vinyl pyridine as a ligand and functional monomer, resp. The new polymer was utilized for modifying a GCE to generate a new electrochem. sensor. Box-Behnken design (BBD) was utilized for optimizing the parameters influencing the peak current. Extremely suitable voltammetric performance was demonstrated for the electrochem. detection of lead with a low detection limit (0.05 ng mL^-1), over a wide linear concentration range (0.1-80 ng mL^-1). This modified electrode as a novel sensor was utilized for determining Pb(II) ions in natural water and in fruit juice with very reasonable outcomes. To complete the study, the researchers used 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Recommanded Product: 2-(1H-Benzo[d]imidazol-2-yl)aniline) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthetic Route of C13H11N3In 2019, Teker, Mine Sen;Karaca, Erhan;Pekmez, Nuran Oezcicek;Tamer, Ugur;Pekmez, Kadir published 《An Enzyme-Free H₂O₂ Sensor Based on Poly(2-Aminophenylbenzimidazole)/Gold Nanoparticles Coated Pencil Graphite Electrode》. 《Electroanalysis》published the findings. The article contains the following contents:

A poly(2-aminophenylbenzimidazole)/gold nanoparticles (P2AB/AuNPs) coated disposable pencil graphite electrode (PGE) was fabricated as an enzyme-free sensor for the H₂O₂ determination P2AB/AuNPs and P2AB were successfully synthesized electrochem. on PGE in acetonitrile for the first time. The coatings were characterized by SEM, X-ray diffraction spectroscopy, Energy-dispersive X-ray spectroscopy, Surface-enhanced Raman spectroscopy, and UV-Vis spectroscopy. AuNPs interacted with P2AB as carrier enhances the electrocatalytic activity towards reduction of H₂O₂. The anal. performance was evaluated in a 100 mM phosphate buffer solution at pH 6.5 by amperometry. The steady state current vs. H₂O₂ concentration is linear in the range of 0.06 to 100 mM (R²=0.992) with a limit of detection 3.67×10^-5 M at -0.8 V vs. SCE and no interference is caused by ascorbic acid, dopamine, uric acid, and glucose. The examination for the sensitive determination of H₂O₂ was conducted in com. available hair oxidant solution The results demonstrate that P2AB/AuNPs/PGE has potential applications as a sensing material for quant. determination of H₂O₂. The experimental procedure involved many compounds, such as 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Synthetic Route of C13H11N3) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Kumar, Amit;Kumar, Ashish;Gupta, Rakesh Kumar;Paitandi, Rajendra Prasad;Singh, Krishna Beer;Trigun, Surendra Kumar;Hundal, Maninder Singh;Pandey, Daya Shankar published 《Cationic Ru(II), Rh(III) and Ir(III) complexes containing cyclic π-perimeter and 2-aminophenyl benzimidazole ligands: Synthesis, molecular structure, DNA and protein binding, cytotoxicity and anticancer activity》. The research results were published in《Journal of Organometallic Chemistry》 in 2016.Product Details of 5805-39-0 The article conveys some information:

Synthesis, characterization, DNA and protein binding as well as anticancer activity of the organometallic complexes [(η⁶-C₆H₆)RuCl(APBI)]Cl (1), [(η⁶-p-MeC₆H₄Prⁱ)RuCl(APBI)]Cl (2), [(η⁶-C₆Me₆)RuCl(APBI)]Cl (3), [(η⁵-C₅Me₅)RhCl(APBI)]Cl·H₂O (4) and [(η⁵-C₅Me₅)IrCl(APBI)]Cl·H₂O (5) containing 2-aminophenyl benzimidazole (APBI) have been described. The complexes 1–5 exhibited strong DNA, protein binding and anticancer activity against cervical cancer (SiHa) cell line. Their binding with calf thymus DNA (CT-DNA) and bovine serum albumin (BSA) have been examined by absorption and emission spectral studies. Strong interactions between complexes and CT-DNA have been affirmed by absorption spectral and EthBr displacement studies, while interaction with BSA via static quenching explored by fluorescence titration, synchronous and 3D fluorescence spectroscopy. The interactions between 1–5 and DNA has also been scrutinized by ¹H NMR spectral studies using guanosine as a model for DNA. These results have been supported by DFT calculations and mol. docking studies. Cytotoxicity, apoptosis and in vitro anticancer activity of 1–5 toward SiHa cell line have been investigated by MTT assay and acridine (AO)/ethidium bromide (EthBr) fluorescence staining. Overall results revealed that DNA and protein binding, as well as anticancer activity of 1–5 follows the order as 5 > 3 > 2 > 1 > 4. And 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) was used in the research process.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Product Details of 5805-39-0) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Formula: C13H11N3In 2018, Matysiak, Joanna;Skrzypek, Alicja;Glaszcz, Urszula;Matwijczuk, Arkadiusz;Senczyna, Bogdan;Wietrzyk, Joanna;Krajewska-Kulak, Elzbieta;Niewiadomy, Andrzej published 《Synthesis and biological activity of novel benzoazoles, benzoazines and other analogs functionalized by 2,4-dihydroxyphenyl moiety》. 《Research on Chemical Intermediates》published the findings. The article contains the following contents:

Novel benzoazoles, benzoazines, benzothiazoles, benzothiazines and other related compounds possessing a 2,4-dihydroxyphenyl moiety were prepared The compounds were obtained by the reaction of sulfinylbis[(2,4-dihydroxyphenyl)methanethione]s with the appropriate heterocyclic amines or hydrazines. Human cancer lines, Candida species and phytopathogenic fungi were used for the evaluation of biol. potency of compounds Addnl., drug-like properties were estimated in silico. The experimental procedure involved many compounds, such as 2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) .

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Formula: C13H11N3) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Seyednejhad, Sajedeh;Khalilzadeh, Mohammad A.;Zareyee, Daryoush;Sadeghifar, Hasan;Venditti, Richard published 《Cellulose nanocrystal supported palladium as a novel recyclable catalyst for Ullmann coupling reactions》. The research results were published in《Cellulose (Dordrecht, Netherlands)》 in 2019.Application of 5805-39-0 The article conveys some information:

A new Pd catalyst chem. bonded to cellulose nanocrystals surfaces was developed. 2-(1H-benzo[d]imidazol-2-yl)aniline (BIA), tosylated cellulose nanocrystals (CNC-TOS) and PdCl₂ were the reactants for the synthesis of the new catalyst designed to be used for the Ullmann reaction. The modified cellulose nano catalyst was characterized with various anal. tools. The catalyst had excellent selectivity and activity in a short reaction time (45 min) and outstanding TON (490) and TOF (1960) values. The nano catalyst was determined to be reusable for at least eight cycles. The Pd catalyst chem. bonded to cellulose nanocrystals surface indicated excellent catalytic efficiency for the Ullmann C-O reaction when it was compared to com. palladium catalysts.2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) were involved in the experimental procedure.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Application of 5805-39-0) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Leal, Jorge;Santos, Lucia;Fernandez-Aroca, Diego M.;Cuevas, J. Vicente;Martinez, M. Angeles;Massaguer, Anna;Jalon, Felix A.;Ruiz-Hidalgo, M. Jose;Sanchez-Prieto, Ricardo;Rodriguez, Ana M.;Castaneda, Gregorio;Dura, Gema;Carrion, M. Carmen;Barrabes, Silvia;Manzano, Blanca R. published 《Effect of the aniline fragment in Pt(II) and Pt(IV) complexes as anti-proliferative agents. Standard reduction potential as a more reliable parameter for Pt(IV) compounds than peak reduction potential》. The research results were published in《Journal of Inorganic Biochemistry》 in 2021.Electric Literature of C13H11N3 The article conveys some information:

The problems of resistance and side effects associated with cisplatin and other chemotherapeutic drugs have boosted research aimed at finding new compounds with improved properties. The use of platinum(IV) prodrugs is one alternative, although there is some controversy regarding the predictive ability of the peak reduction potentials. In the work described here a series of fourteen chloride Pt(II) and Pt(IV) compounds was synthesized and fully characterized. The compounds contain different bidentate arylazole heterocyclic ligands. Their cytotoxic properties against human lung carcinoma (A549), human breast carcinoma (MCF7) and human colon carcinoma (HCT116 and HT29) cell lines were studied. A clear relationship between the type of ligand and the anti-proliferative properties was found, with the best results obtained for the Pt(II) compound that contains an aniline fragment, (13), thus evidencing a pos. effect of the NH₂ group. Stability and aquation studies in DMSO, DMF and DMSO/water mixtures were carried out on the active complexes and an in-depth anal. of the two aquation processes, including DFT anal., of 13 was undertaken. It was verified that DNA was the target and that cell death occurred by apoptosis in the case of 13. Furthermore, the cytotoxic derivatives did not exhibit haemolytic activity. The reduction of the Pt(IV) compounds whose Pt(II) congeners were active was studied by several techniques. It was concluded that the peak reduction potential was not useful to predict the ability for reduction However, a correlation between the cytotoxic activity and the standard reduction potential was found.2-(1H-Benzo[d]imidazol-2-yl)aniline (cas: 5805-39-0) were involved in the experimental procedure.

2-(1H-Benzo[d]imidazol-2-yl)aniline(cas:5805-39-0 Electric Literature of C13H11N3) is a chemical reagent used in the synthesis of small molecule inhibitors targeting ubiquitin-like domains for treatments of diseases caused by the cellular accumulation of damaged proteins.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem