Tang, Kai et al. published their research in Xiyou Jinshu Yu Yingzhi Hejin in 2010 |CAS: 5709-67-1

The Article related to benzimidazole corrosion inhibitor cemented carbide synthesis, Nonferrous Metals and Alloys: Corrosion (If The Primary Interest Is In The Metal), Erosion, Cavitation, Tribology, and Oxidation and other aspects.Related Products of 5709-67-1

On September 20, 2010, Tang, Kai; Yan, Jie; Sun, Ya-li; Li, Li published an article.Related Products of 5709-67-1 The title of the article was Synthesis of new benzimidazole corrosion inhibitor applied in cemented carbide. And the article contained the following:

Three kinds of benzimidazole ramification including 2-(o/i/p)-nitrobenzimidazole were synthesized by one step with o-phenylenediamine and nitrobenzaldehyde as the materials. And they were applied in cemented carbide anticorrosion. The results show that the optimal synthesis tech. parameters are as follows: the ratio of o-phenylenediamine to nitrobenzaldehyde is 1.2, reaction temperature 60掳C, and heating duration 20 min. The m.p. anal. results show that the synthetic product is the target product. The corrosion inhibition rate of the new corrosion inhibitor is up to 95.6%, better than that of the similar domestic products. The experimental process involved the reaction of 2-Nitro-1H-benzo[d]imidazole(cas: 5709-67-1).Related Products of 5709-67-1

The Article related to benzimidazole corrosion inhibitor cemented carbide synthesis, Nonferrous Metals and Alloys: Corrosion (If The Primary Interest Is In The Metal), Erosion, Cavitation, Tribology, and Oxidation and other aspects.Related Products of 5709-67-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Zheng, Jun Ping et al. published their research in Journal of Information Recording in 1997 |CAS: 5709-67-1

The Article related to photog emulsion antifoggant agent mercaptobenzimidazole mercaptobenzothiazole, Radiation Chemistry, Photochemistry, and Photographic and Other Reprographic Processes: Silver Halide Photographic Chemistry and Processes and other aspects.Category: imidazoles-derivatives

On June 30, 1997, Zheng, Jun Ping; Chen, Ping; Hu, Xiu Jie; Zheng, De Shui published an article.Category: imidazoles-derivatives The title of the article was Effects of several antifoggants on photographic properties of photographic emulsions. And the article contained the following:

Effects of several antifoggants on sensitivity and fog properties of unsensitized- and sulfur sensitized cubic AgCl emulsion have been investigated. The results indicate that upon appropriate addition of antifoggant it can not only inhibit the increase of fog, but most important, also significantly increase the sensitivity of the emulsion (more than 2 times). Adsorption of the antifoggant on the surface of AgCl grains and the effect on the concentration of interstitial silver ions have been studied for elucidating the reason for the modification of photog. properties. Possible mechanism relating the sensitizing effect to electron traps was discussed and suggested. The experimental process involved the reaction of 2-Nitro-1H-benzo[d]imidazole(cas: 5709-67-1).Category: imidazoles-derivatives

The Article related to photog emulsion antifoggant agent mercaptobenzimidazole mercaptobenzothiazole, Radiation Chemistry, Photochemistry, and Photographic and Other Reprographic Processes: Silver Halide Photographic Chemistry and Processes and other aspects.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Debnath, Asim Kumar et al. published their research in Environmental and Molecular Mutagenesis in 1992 |CAS: 5709-67-1

The Article related to hydrophobicity qsar mutagenicity heteroaromatic nitro compound, structure aromatic nitro compound mutagenicity hydrophobicity, salmonella aromatic nitro compound mutagenicity structure and other aspects.Electric Literature of 5709-67-1

On January 31, 1992, Debnath, Asim Kumar; Lopez de Compadre, Rosa L.; Shusterman, Alan J.; Hansch, Corwin published an article.Electric Literature of 5709-67-1 The title of the article was Quantitative structure-activity relationship investigation of the role of hydrophobicity in regulating mutagenicity in the Ames test: 2: Mutagenicity of aromatic and heteroaromatic nitro compounds in Salmonella typhimurium TA100. And the article contained the following:

A quant. structure-activity relationship (QSAR) is derived for the mutagenic activity of 117 aromatic and heteroaromatic nitro compounds acting on S. typhimurium TA100. Relative mutagenic activity is bilinearly dependent on hydrophobicity, with an optimal log P of 5.44, and is linearly dependent on the energy of the LUMO of the nitro compound The dependence of mutagenic activity on hydrophobicity and electronic effects is very similar for TA98 and TA100. Mutagenic activity in TA100 does not depend on the size of the aromatic ring system, as its does in TA98. The effect of the choice of assay organism, TA98 vs. TA100, on nitroarene QSAR is similar to the effect previously found for aminoarenes. Lateral verification of QSARs is presented as a tool for establishing the significance of a new QSAR. The experimental process involved the reaction of 2-Nitro-1H-benzo[d]imidazole(cas: 5709-67-1).Electric Literature of 5709-67-1

The Article related to hydrophobicity qsar mutagenicity heteroaromatic nitro compound, structure aromatic nitro compound mutagenicity hydrophobicity, salmonella aromatic nitro compound mutagenicity structure and other aspects.Electric Literature of 5709-67-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Debnath, Asim Kumar et al. published their research in Environmental and Molecular Mutagenesis in 1992 |CAS: 5709-67-1

The Article related to hydrophobicity qsar mutagenicity heteroaromatic nitro compound, structure aromatic nitro compound mutagenicity hydrophobicity, salmonella aromatic nitro compound mutagenicity structure and other aspects.Electric Literature of 5709-67-1

On January 31, 1992, Debnath, Asim Kumar; Lopez de Compadre, Rosa L.; Shusterman, Alan J.; Hansch, Corwin published an article.Electric Literature of 5709-67-1 The title of the article was Quantitative structure-activity relationship investigation of the role of hydrophobicity in regulating mutagenicity in the Ames test: 2: Mutagenicity of aromatic and heteroaromatic nitro compounds in Salmonella typhimurium TA100. And the article contained the following:

A quant. structure-activity relationship (QSAR) is derived for the mutagenic activity of 117 aromatic and heteroaromatic nitro compounds acting on S. typhimurium TA100. Relative mutagenic activity is bilinearly dependent on hydrophobicity, with an optimal log P of 5.44, and is linearly dependent on the energy of the LUMO of the nitro compound The dependence of mutagenic activity on hydrophobicity and electronic effects is very similar for TA98 and TA100. Mutagenic activity in TA100 does not depend on the size of the aromatic ring system, as its does in TA98. The effect of the choice of assay organism, TA98 vs. TA100, on nitroarene QSAR is similar to the effect previously found for aminoarenes. Lateral verification of QSARs is presented as a tool for establishing the significance of a new QSAR. The experimental process involved the reaction of 2-Nitro-1H-benzo[d]imidazole(cas: 5709-67-1).Electric Literature of 5709-67-1

The Article related to hydrophobicity qsar mutagenicity heteroaromatic nitro compound, structure aromatic nitro compound mutagenicity hydrophobicity, salmonella aromatic nitro compound mutagenicity structure and other aspects.Electric Literature of 5709-67-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Jahan, Humera et al. published their research in Medicinal Chemistry (Sharjah, United Arab Emirates) in 2017 |CAS: 5709-67-1

The Article related to fibroblast cell proliferation ros protein glycation 6 nitrobenzimidazole derivative, 6-nitrobenzimidazole derivatives, advanced glycation end products, fructose-derived ages, intracellular oxidative stress, protein glycation and other aspects.Recommanded Product: 2-Nitro-1H-benzo[d]imidazole

On September 30, 2017, Jahan, Humera; Choudhary, Muhammad I.; Shah, Zarbad; Khan, Khalid M.; Atta-ur-Rahman published an article.Recommanded Product: 2-Nitro-1H-benzo[d]imidazole The title of the article was Derivatives of 6-Nitrobenzimidazole Inhibit Fructose-Mediated Protein Glycation and Intracellular Reactive Oxygen Species Production. And the article contained the following:

Background: Benzimidazoles are important pharmacophores in drug discovery, and currently its derivatives such as flubendazole, omeprazole, and astemizole are used for the treatment of anthelmintic, ulcerative, and histaminic diseases, resp.

Objectives: The aim of the current study was to investigate the antiglycation activity of nitrobenzimidazole derivatives against fructose-mediated human serum albumin (HSA) glycation. The study was also aimed at investigating the effects of newly identified antiglycation inhibitors on AGEsinduced intracellular reactive oxygen species (ROS) production, and associated impaired proliferation of the hepatocytes.

Methods: The present study focuses on the antiglycation activity of 6-nitrobenzimidazole derivatives 1-13 in in-vitro human serum albumin (HSA)- fructose model. These derivatives were also identified as non-toxic against 3T3 mouse fibroblast cell-line in MTT-based assay. The effect of the most promising derivative 5, 4-(6-nitro-1H-benzimidazol-2-yl)-1,2,3-benzenetriol, was studied in a dose dependent manner, co-incubated with fructose-derived AGEs (0- 200 g/mL) on rat hepatocytes proliferation and associated intracellular generation of ROS via MTT-based assay and DCFHDA technique, resp.

Results: We found that derivative 5 ameliorates the elevated intracellular oxidative stress and associated diminished proliferation of the hepatocytes in response to AGEs.

Conclusion: In conclusion, we identified novel 6-nitrobenzimidazole derivatives as antiglycation agents through in-vitro, and cell-based models. The experimental process involved the reaction of 2-Nitro-1H-benzo[d]imidazole(cas: 5709-67-1).Recommanded Product: 2-Nitro-1H-benzo[d]imidazole

The Article related to fibroblast cell proliferation ros protein glycation 6 nitrobenzimidazole derivative, 6-nitrobenzimidazole derivatives, advanced glycation end products, fructose-derived ages, intracellular oxidative stress, protein glycation and other aspects.Recommanded Product: 2-Nitro-1H-benzo[d]imidazole

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem