Kafshgari, Morteza Hasanzadeh’s team published research in ACS Applied Materials & Interfaces in 2019 | CAS: 530-62-1

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications and polypeptides. It also used to make β-keto sulfones and sulfoxides, lead sequestering agents, and β-enamino acid derivatives.Electric Literature of C7H6N4O

《Intracellular Drug Delivery with Anodic Titanium Dioxide Nanotubes and Nanocylinders》 was written by Kafshgari, Morteza Hasanzadeh; Mazare, Anca; Distaso, Monica; Goldmann, Wolfgang H.; Peukert, Wolfgang; Fabry, Ben; Schmuki, Patrik. Electric Literature of C7H6N4OThis research focused ontitanium dioxide nanotube nanocylinder drug carrier; electrochemical anodization; intracellular drug delivery; nanocylinders; nanotubes; titanium dioxide. The article conveys some information:

Titanium dioxide (TiO2) holds remarkable promises for developing current theranostic strategies. Anodic TiO2 nanostructures as a porous scaffold have offered a broad range of useful theranostic properties; however, previous attempts to generate single and uniform TiO2 one-dimensional nanocarriers from anodic nanotube arrays have resulted in a broad cluster size distribution of arbitrarily broken tubes that are unsuitable for therapeutic delivery systems due to poor bio-distribution and the risk of introducing tissue inflammation. Here, we achieve well-separated, uniformly shaped anodic TiO2 nanotubes and nanocylinders through a time-varying electrochem. anodization protocol that leads to the generation of planar sheets of weakly connected nanotubes with a defined fracture point near the base. Subsequent sonication cleanly detaches the nanotubes from the base. Depending on the position of the fracture point, we can fabricate single anodic nanocylinders that are open on both ends, or nanotubes that are closed on one end. We go on to show that anodic nanotubes and nanocylinders are non-toxic at therapeutic concentrations When conjugated with the anticancer drug doxorubicin using a pH-responsive linker, they are readily internalized by cells and subsequently release their drug cargo into acidic intracellular compartments. Our results demonstrate that uniformly sized anodic TiO2 nanotubes and nanocylinders are suitable for subcellular delivery of therapeutic agents in cancer therapy. In the part of experimental materials, we found many familiar compounds, such as Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Electric Literature of C7H6N4O)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications and polypeptides. It also used to make β-keto sulfones and sulfoxides, lead sequestering agents, and β-enamino acid derivatives.Electric Literature of C7H6N4O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Sherje, Atul P.’s team published research in Journal of Materials Science: Materials in Medicine in 2019 | CAS: 530-62-1

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications and polypeptides. It also used to make β-keto sulfones and sulfoxides, lead sequestering agents, and β-enamino acid derivatives.Recommanded Product: 530-62-1

Recommanded Product: 530-62-1In 2019 ,《CDI cross-linked beta-cyclodextrin nanosponges of paliperidone: synthesis and physicochemical characterization》 was published in Journal of Materials Science: Materials in Medicine. The article was written by Sherje, Atul P.; Surve, Anushree; Shende, Pravin. The article contains the following contents:

Abstract: Paliperidone (PLP) is an antipsychotic drug indicated for treatment and management of schizophrenia. The current study demonstrates potential of PLP-loaded beta-cyclodextrin-based nanosponges (CDNS) for solubility enhancement and prolonged release of PLP. The inclusion complexes of PLP with carbonyldiimidazole (CDI) cross-linked nanosponges were synthesized. The drug-loaded CDNS were characterized for particle size, zeta potential, encapsulation efficiency, stability study, in vitro drug release studies. The interaction of PLP with CDNS was ascertained by FTIR, DSC and PXRD studies. The particle size and zeta potential values were sufficient to obtain stable formulations. Solubility was significantly increased and in vitro drug release studies revealed prolonged release of PLP from the CDNS for 6 h. PXRD study revealed that the crystallinity of PLP was decreased due to complexation with the CDNS. Thus, cyclodextrin-based nanosponges represent a novel approach for solubility enhancement and improved dissolution of selected model drug PLP. [Figure not available: see fulltext.]. The experimental part of the paper was very detailed, including the reaction process of Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Recommanded Product: 530-62-1)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications and polypeptides. It also used to make β-keto sulfones and sulfoxides, lead sequestering agents, and β-enamino acid derivatives.Recommanded Product: 530-62-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Mukherjee, Shuvam’s team published research in International Journal of Biological Macromolecules in 2021 | CAS: 530-62-1

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Related Products of 530-62-1

Mukherjee, Shuvam; Bera, Kaushik; Jana, Subrata; Pal, Saikat; Anand, Namrata; Ray, Bimalendu; Ray, Sayani published an article in 2021. The article was titled 《Conjugation reaction with ferulic acid boosts the antioxidant property of arabinogalactan-protein and enhances its ability to form complex with β-lactoglobulin》, and you may find the article in International Journal of Biological Macromolecules.Related Products of 530-62-1 The information in the text is summarized as follows:

Ferulic acid was chem. grafted onto the arabinogalactan protein of Aegle marmelos fruit gum using 1,1′-carbonyldiimidazole as coupling reagent. Thus, grafted polysaccharides with different degrees of substitution were prepared and then characterized by gas chromatog./mass spectrometry, size exclusion chromatog., and UV-visible, infra-red, and NMR spectroscopic investigations. Fluorescence spectroscopic investigation showed hydrophobic microdomain formation in grafted polymers. The antioxidant activities of the derivatives, as determined by the 2,2-diphenyl-1-(2,4,6-trinitrophenyl) hydrazyl radical assay, were strong and increases with increasing the degree of feruloylation. Compared to parental arabinogalactan protein (K = 2.38 x 106 M-1), these grafted polymers bind more strongly with β-lactoglobulin (K = 11.4 x 106 M-1 and 8.19 x 106 M-1). Given that gum polysaccharides are valuable component in functional foods, synthesis of antioxidative graft polymer possessing good compatibility with β-lactoglobulin may have important implication. The experimental part of the paper was very detailed, including the reaction process of Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Related Products of 530-62-1)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Related Products of 530-62-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Borges-Munoz, Amaris’s team published research in Journal of Pharmaceutical and Biomedical Analysis in 2022 | CAS: 530-62-1

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Recommanded Product: Di(1H-imidazol-1-yl)methanone

In 2022,Borges-Munoz, Amaris; Patel, Harshkumar; Tattersall, Peter published an article in Journal of Pharmaceutical and Biomedical Analysis. The title of the article was 《Derivatization and determination of residual N,N-Carbonyldiimidazole by LC for an in-process control test》.Recommanded Product: Di(1H-imidazol-1-yl)methanone The author mentioned the following in the article:

For the robust anal. of N,N-Carbonyldiimidazole (CDI), its derivatization into a more stable compound may be needed. Herein, the reaction of CDI with N-benzylmethylamine followed by LC-UV quant. anal. was explored. Reaction conditions as well as LC method feasibility were demonstrated by qualification of selectivity from other impurities and reagents, linearity across a range of 0.05-0.15%weight/weight, spike and recovery across a range of 0.05-0.15%weight/weight, reaction reproducibility with various samples, reagents and anal. chemists, and sample stability of over 24 h. Rapid and quant. derivatization of residual CDI was achieved at 0.1% weight/weight relative to the synthetic product under consideration. A fit-for-purpose limit test using a RPLC-UV method as an in-process control for the reaction completion of product, at scale, was successfully implemented and executed. In the experiment, the researchers used many compounds, for example, Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Recommanded Product: Di(1H-imidazol-1-yl)methanone)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Recommanded Product: Di(1H-imidazol-1-yl)methanone

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Iacobucci, Claudio’s team published research in Journal of the American Society for Mass Spectrometry in 2019 | CAS: 530-62-1

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications and polypeptides. It also used to make β-keto sulfones and sulfoxides, lead sequestering agents, and β-enamino acid derivatives.Application In Synthesis of Di(1H-imidazol-1-yl)methanone

The author of 《The First MS-Cleavable, Photo-Thiol-Reactive Cross-Linker for Protein Structural Studies》 were Iacobucci, Claudio; Piotrowski, Christine; Rehkamp, Anne; Ihling, Christian H.; Sinz, Andrea. And the article was published in Journal of the American Society for Mass Spectrometry in 2019. Application In Synthesis of Di(1H-imidazol-1-yl)methanone The author mentioned the following in the article:

Cleavable crosslinkers are gaining increasing importance for chem. crosslinking/mass spectrometry (MS) as they permit a reliable and automated data anal. in structural studies of proteins and protein assemblies. Here, the authors introduce 1,3-diallylurea (DAU) as the first CID-MS/MS-cleavable, photo-thiol-reactive crosslinker. DAU is a com. available, inexpensive reagent that efficiently undergoes an anti-Markovnikov hydrothiolation with cysteine residues in the presence of a radical initiator upon UV-A irradiation Radical cysteine crosslinking proceeds via an orthogonal “”click reaction”” and yields stable alkyl sulfide products. DAU reacts at physiol. pH and crosslinking reactions with peptides, and proteins can be performed at temperatures as low as 4°. The central urea bond is efficiently cleaved upon collisional activation during tandem MS experiments generating characteristic product ions. This improves the reliability of automated crosslink identification. Different radical initiators have been screened for the crosslinking reaction of DAU using the thiol-containing compounds cysteine and glutathione. The authors’ concept has also been exemplified for the biol. relevant proteins bMunc13-2 and retinal guanylyl cyclase-activating protein-2. After reading the article, we found that the author used Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Application In Synthesis of Di(1H-imidazol-1-yl)methanone)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications and polypeptides. It also used to make β-keto sulfones and sulfoxides, lead sequestering agents, and β-enamino acid derivatives.Application In Synthesis of Di(1H-imidazol-1-yl)methanone

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Climova, Alina’s team published research in Journal of Food Science and Technology (New Delhi, India) in 2021 | CAS: 530-62-1

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications and polypeptides. It also used to make β-keto sulfones and sulfoxides, lead sequestering agents, and β-enamino acid derivatives.Reference of Di(1H-imidazol-1-yl)methanone

Climova, Alina; Ibrahim, Monica N. G.; Salamahina, Alisa; Savin, Artemii M.; Dukhinova, Marina S.; Barakova, Nadezhda V.; Krivoshapkina, Elena F. published an article in 2021. The article was titled 《Application of extracted β-glucan from oat for β-carotene encapsulation》, and you may find the article in Journal of Food Science and Technology (New Delhi, India).Reference of Di(1H-imidazol-1-yl)methanone The information in the text is summarized as follows:

The cell walls of cereals are rich sources of polysaccharide β-glucan. In this study, the β-glucan was extracted from oat bran using the hot-water extraction method and dried in a pure powder form. The concentration of the β-glucan in the extract was determined using the L-cysteine sulfuric acid method. The results showed that the yield of β-glucan using the hot-water extraction method is the highest compared to its yield achieved by enzymic, acid, and alk. methods. In this paper, the usage of the β-glucan as a coating material for a water-insoluble carotenoid is considered. This study demonstrates for the first time the encapsulation of β-carotene with modified octanoic acid β-glucan. It implements to obtain a stable encapsulated polysaccharide-carotenoid system, which has been studied by a set of physicochem. methods and a cytotoxic anal. was performed on the HCT-116 cell line. The SEM image of the resulting encapsulated system is perfectly correlated with the DLS data, which has determined the size of MG capsules at 200 nm. The cytotoxic anal. demonstrates that the cell viability was more than 70%, which indicates its potential using in the food industry. The experimental process involved the reaction of Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Reference of Di(1H-imidazol-1-yl)methanone)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a coupling agent in the synthesis of dipolar polyamides for nonlinear optical applications and polypeptides. It also used to make β-keto sulfones and sulfoxides, lead sequestering agents, and β-enamino acid derivatives.Reference of Di(1H-imidazol-1-yl)methanone

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Varan, Cem’s team published research in International Journal of Pharmaceutics (Amsterdam, Netherlands) in 2020 | CAS: 530-62-1

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Synthetic Route of C7H6N4O

《Preparation and characterization of cyclodextrin nanosponges for organic toxic molecule removal》 was published in International Journal of Pharmaceutics (Amsterdam, Netherlands) in 2020. These research results belong to Varan, Cem; Anceschi, Anastasia; Sevli, Serhat; Bruni, Natascia; Giraudo, Leonardo; Bilgic, Elif; Korkusuz, Petek; Iskit, Alper B.; Trotta, Francesco; Bilensoy, Erem. Synthetic Route of C7H6N4O The article mentions the following:

Cyclodextrin-based nanosponges (CD-NS) are considered as safe and biocompatible systems for removing toxic mols. from the body. Rapid removal of toxic mols. that are formed in the body from certain food constituents, is relevant especially for patients affected by chronic kidney disease. Within the scope of this study, innovative cyclodextrin polymers were synthesized to form nanosponges able to remove indole, before it could form the toxic indoxyl sulfate in the body. Furthermore, in vivo studies were carried out using the two optimal CD-NS formulations by assessing physicochem. properties, stability, indole adsorption capacity and in vitro cytotoxicity. NS prepared from β-cyclodextrin crosslinked with toluene diisocyanate was found to be the most effective NS with an in vitro indole adsorption capacity of over 90%. In addition, this derivative was more stable in gastrointestinal media. Animal studies further revealed that oral CD-NSs did not tend to accumulate and damage gastrointestinal tissues and are excreted from the GI tract with minimal absorption. In conclusion, this study suggests that CD-NS formulations are effective and safe in removing toxic mols. from the body. Their potential use in veterinary or human medicine could reduce dialysis frequency and avoid hepatic and cardiac toxicity avoiding the indole formation. The experimental process involved the reaction of Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Synthetic Route of C7H6N4O)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Synthetic Route of C7H6N4O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Shishkina, Svitlana V.’s team published research in Acta Crystallographica, Section C: Structural Chemistry in 2020 | CAS: 530-62-1

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Related Products of 530-62-1

《Concomitant polymorphic forms of 3-cyclopropyl-5-(2-hydrazinylpyridin-3-yl)-1,2,4-oxadiazole》 was published in Acta Crystallographica, Section C: Structural Chemistry in 2020. These research results belong to Shishkina, Svitlana V.; Konovalova, Irina S.; Karpina, Veronika R.; Kovalenko, Svitlana S.; Kovalenko, Sergiy M.; Bunyatyan, Natalya D.. Related Products of 530-62-1 The article mentions the following:

The dipharmacophore compound 3-cyclopropyl-5-(2-hydrazinylpyridin-3-yl)-1,2,4-oxadiazole, C10H11N5O, was studied on the assumption of its potential biol. activity. Two concomitant polymorphs were obtained on crystallization from isopropanol solution and these were thoroughly studied. Identical conformations of the mols. are found in both structures despite the low difference in energy between the four possible conformers. The two polymorphs differ crucially with respect to their crystal structures. A centrosym. dimer formed due to both stacking interactions of the ‘head-to-tail’ type and N-H…N(π) hydrogen bonds is the building unit in the triclinic structure. The dimeric building units form an isotropic packing. In the orthorhombic polymorphic structure, the mols. form stacking interactions of the ‘head-to-head’ type, which results in their organization in a column as the primary basic structural motif. The formation of N-H···N(lone pair) hydrogen bonds between two neighboring columns allows the formation of a double column as the main structural motif. The correct packing motifs in the two polymorphs could not be identified without calculations of the pairwise interaction energies. The triclinic structure has a higher d. and a lower (by 0.60 kcal mol-1) lattice energy according to periodic calculations compared to the orthorhombic structure. This allows us to presume that the triclinic form of 3-cyclopropyl-5-(2-hydrazinylpyridin-3-yl)-1,2,4-oxadiazole is the more stable. In the experiment, the researchers used Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Related Products of 530-62-1)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Related Products of 530-62-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Lah, Zur Mira Azizah Nor Haiza’s team published research in Journal of Pharmaceutical and Biomedical Analysis in 2019 | CAS: 530-62-1

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Category: imidazoles-derivatives

The author of 《An Electrochemical Sandwich Immunosensor for the Detection of HER2 using Antibody-Conjugated PbS Quantum Dot as a label》 were Lah, Zur Mira Azizah Nor Haiza; Ahmad, Shahrul Ainliah Alang; Zaini, Muhammad Safwan; Kamarudin, Mazliana Ahmad. And the article was published in Journal of Pharmaceutical and Biomedical Analysis in 2019. Category: imidazoles-derivatives The author mentioned the following in the article:

A facile electrochem. sandwich immunosensor for the detection of a breast cancer biomarker, the human epidermal growth factor receptor 2 (HER2), was designed, using lead sulfide quantum dots-conjugated secondary HER2 antibody (Ab2-PbS QDs) as a label. Using Ab2-PbS QDs in the development of electrochem. immunoassays leads to many advantages such as straightforward synthesis and well-defined stripping signal of Pb(II) through acid dissolution, which in turn yields better sensing performance for the sandwiched immunosensor. In the bioconjugation of PbS QDs, the available amine and hydroxyl groups from secondary anti-HER2 and capped PbS QDs were bound covalently together via carbonyldiimidazole (CDI) acting as a linker. In order to quantify the biomarker, SWV signal was obtained, where the Pb2+ ions after acid dissolution in HCl was detected. The plated mercury film SPCE was also detected in situ. Under optimal conditions, HER2 was detected in a linear range from 1-100 ng/mL with a limit of detection of 0.28 ng/mL. The measures of satisfactory recoveries were 91.3% to 104.3% for the spiked samples, displaying high selectivity. Therefore, this method can be applied to determine HER2 in human serum. In the experiment, the researchers used many compounds, for example, Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Category: imidazoles-derivatives)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Pokhodylo, Nazariy’s team published research in Acta Crystallographica, Section E: Crystallographic Communications in 2020 | CAS: 530-62-1

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Computed Properties of C7H6N4O

《Synthesis, crystal structure and Hirshfeld surface analysis of N-(4-chlorophenyl)-5-cyclopropyl-1-(4-methoxyphenyl)-1H-1,2,3-triazole-4-carboxamide》 was published in Acta Crystallographica, Section E: Crystallographic Communications in 2020. These research results belong to Pokhodylo, Nazariy; Slyvka, Yurii; Pavlyuk, Volodymyr. Computed Properties of C7H6N4O The article mentions the following:

The title compound, C19H17ClN4O2, was obtained via a two-step synthesis involving the enol-mediated click Dimroth reaction of 4-azidoanisole with Me 3-cyclopropyl-3-oxopropanoate leading to the 5-cyclopropyl-1-(4-methoxyphenyl)-1H-1,2,3-triazole-4-carboxylic acid and subsequent acid amidation with 4-chloroaniline by 1,1′-carbonyldiimidazole (CDI). It crystallizes in space group P21/n, with one mol. in the asym. unit. In the extended structure, two mols. arranged in a near coplanar fashion relative to the triazole ring planes are interconnected by N-H···N and C-H···N hydrogen bonds into a homodimer. The formation of dimers is a consequence of the above interaction and the edge-to-face stacking of aromatic rings, which are turned by 58.0 (3)° relative to each other. The dimers are linked by C-H···O interactions into ribbons. DFT calculations demonstrate that the frontier MOs are well separated in energy and the HOMO is largely localized on the 4-chlorophenyl amide motif while the LUMO is associated with aryltriazole grouping. A Hirshfeld surface anal. was performed to further analyze the intermol. interactions. After reading the article, we found that the author used Di(1H-imidazol-1-yl)methanone(cas: 530-62-1Computed Properties of C7H6N4O)

Di(1H-imidazol-1-yl)methanone(cas: 530-62-1) is a peptide coupling reagent,it is used in the synthesis of peptides. Reacts readily with carboxylic acids to form acyl imidazoles; subsequent reaction with amines to form amides goes smoothly.Computed Properties of C7H6N4O

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem