41384-83-2, name is 4-Nitro-1-phenyl-1H-imidazole, belongs to imidazoles-derivatives compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. Recommanded Product: 41384-83-2
To a solution of 4-nitro-l -phenyl- lH-imidazole (0.17 g, 0.89 mmol) in THF (5 ml) was added 10% Pd/C (0.1 g), at rt. The reaction mixture was purged with H2gas for 2 h at rt. The resulting reaction mixture was carefully filtered through celite hyflow and concentrated under reduced pressure to yield 1 -phenyl- lH-imidazol-4-amine, LCMS: Method C, 2.86 min, MS: ES+ 159.93.This material was directly used for the next step without further purification.
The synthetic route of 41384-83-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; MISSION THERAPEUTICS LIMITED; KEMP, Mark Ian; WOODROW, Michael David; (63 pag.)WO2017/109488; (2017); A1;,
Imidazole – Wikipedia,
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