Some common heterocyclic compound, 40828-54-4, name is 1H-Benzo[d]imidazole-2-sulfonic acid, molecular formula is C7H6N2O3S, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. SDS of cas: 40828-54-4
STEP A 2-(3-Hydroxypropylamino)benzimidazole Heat at 145-150 C. for two hours a mixture of 5 g (25 mmol) of 2-benzimidazolesulfonic acid and 5.7 ml (75 mmol) of 3-aminopropanol. Cool to 90 C. and add 15 ml of cold water, with vigorous stirring, until a precipitate is formed. Maintain at a temperature of approximately 4 C. for one night, filter the title compound precipitate, wash with cold water and dry. Yield: 95% Melting point: 139-140 C.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 40828-54-4, its application will become more common.
Reference:
Patent; Adir Et Compagnie; US5623073; (1997); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem