Related Products of 380177-22-0, The chemical industry reduces the impact on the environment during synthesis 380177-22-0, name is (5-Chloro-1-methyl-1H-benzo[d]imidazol-2-yl)methanol, I believe this compound will play a more active role in future production and life.
A solution of (5-CHLORO-1-METHYL-1H-BENZIMIDAZOL-2-YL) METHANOL (1.5 g, 7.7 mmol) dissolved in CH2CI2 at room temperature was treated with Dess-Martin periodinane (4.9 g, 11.5 mmol). The reaction was stirred for 15 hours before the solvent was removed. The residue was purified by flash column chromatography (0-3% MeOH in CH2CI2) to give the product (1.0 g, 66% YIELD). 1H NMR (300 MHz, CDCI3) 6 : 4.16 (s, 3 H), 7.40-7. 47 (m, 2 H), 7.90-7. 93 (m, 1 H), 10.11 (s, 1 H).
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Reference:
Patent; PFIZER INC.; WO2004/74270; (2004); A2;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem