Category: 3543-73-5

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Computed Properties of C14H19N3O2, 3543-73-5, Name is Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, SMILES is O=C(OCC)CCCC1=NC2=CC(N)=CC=C2N1C, in an article , author is Kazemi, Mosstafa, once mentioned of 3543-73-5.

Reusable nanomagnetic catalysts in synthesis of imidazole scaffolds

Molecules containing imidazole scaffolds are very important in pharmaceutical and medicinal chemistry due to their excellent biological activities application in synthesis of natural products. In recent times, a variety of procedures have been reported in the literature for the synthesis of imidazole derivatives. Nanomagnetic catalysts have received significant attention because of their easy separation and high activity. Now, in this review, we focused on the catalytic activity of nanomagnetic catalysts in synthesis of imidazole derivatives with the goal of stimulating further progresses in this field.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 3543-73-5, you can contact me at any time and look forward to more communication. Computed Properties of C14H19N3O2.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 3543-73-5, Name is Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, molecular formula is C14H19N3O2. In an article, author is Jiang, Weidong,once mentioned of 3543-73-5, Quality Control of Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate.

Hydrolytic cleavage of p-nitrophenyl picolinate by mononuclear Zn(II) and Co(II) complexes with imidazole derivative in CTAB micellar solution

One new hydroxyl-functionalized imidazole derivative (L) was synthesized and characterized. Further, the related mononuclear zinc(II) and cobalt(II) complexes were prepared and used as mimic hydrolases to catalyze the hydrolytic cleavage of p-nitrophenyl picolinate (PNPP) in buffered aqueous solution and a micellar solution of cetyltrimethylammonium bromide (CTAB). Observations show that for all of catalytic systems, the hydrolysis of PNPP was pH-dependent in the pH range of 7.00-8.20. Besides, hydrolysis rates of PNPP displayed a constant increase with the increasing concentration of substrate. In the case of CoL-containing system, moreover, much greater acceleration for PNPP hydrolysis was observed in comparison with the ZnL-containing system. However, micellar effect of CTAB micelle aggregates on the PNPP hydrolysis was not obvious only showing 1.0 similar to aEuro parts per thousand 1.3 folds rate difference in contrast to buffered aqueous solution.

Interested yet? Keep reading other articles of 3543-73-5, you can contact me at any time and look forward to more communication. Quality Control of Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate.

Chemistry, like all the natural sciences, Computed Properties of C14H19N3O2, begins with the direct observation of nature¡ª in this case, of matter.3543-73-5, Name is Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, SMILES is O=C(OCC)CCCC1=NC2=CC(N)=CC=C2N1C, belongs to imidazoles-derivatives compound. In a document, author is Jayabharathi, Jayaraman, introduce the new discover.

Physicochemical and solvatochromic analysis of an imidazole derivative as NLO material

Bioactive imidazole derivative, 2-(2,4-difluorophenyl)-1-phenyl-1H-imidazo[4,54][1,10]phenanthroline, has been synthesized and characterized by IR, UV-vis, NMR and elemental (CHN) analysis. The electric dipole moment (mu) and the hyperpolarizability (beta) have been studied both experimentally and theoretically, which reveals that the synthesized imidazole derivative possesses non-linear optical (NLO) behavior. This chromophore possess more appropriate ratio of off-diagonal versus diagonal beta tensorial component (r=beta(xyy)/beta(xxx) = -0.19) which reflects the in plane nonlinearity anisotropy. Since they have largest mu beta(0) value, the reported imidazole can be used as potential NLO material. Within this context, reasonable conclusions concerning the steric hindrance in the chromospheres, push-pull character, hyperpolarizability of the imidazole and their application as NLO materials will be drawn. The solvent effect on the absorption and fluorescence bands was analyzed by a multi-component linear regression in which several solvent parameters were analyzed simultaneously. (C) 2011 Elsevier B.V. All rights reserved.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 3543-73-5. Computed Properties of C14H19N3O2.

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 3543-73-5, Name is Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, molecular formula is C14H19N3O2, belongs to imidazoles-derivatives compound. In a document, author is Starchak, VG, introduce the new discover, SDS of cas: 3543-73-5.

Inhibiting activity of mono-, bi-, and tricyclic imidazole derivatives

The quantitative correlation between the chemical structure of mono-, bi-, and tricyclic imidazole derivatives and specific effects of the St.20 steel inhibition is studied.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 3543-73-5. SDS of cas: 3543-73-5.

Chemistry, like all the natural sciences, SDS of cas: 3543-73-5, begins with the direct observation of nature¡ª in this case, of matter.3543-73-5, Name is Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, SMILES is O=C(OCC)CCCC1=NC2=CC(N)=CC=C2N1C, belongs to imidazoles-derivatives compound. In a document, author is Shafaei, Faezeh, introduce the new discover.

Green Synthesis of Imidazole Derivatives via Fe3O4-MNPs as Reusable Catalyst

In this research, a one-pot, efficient, and high yielding procedure for the synthesis of imidazole derivatives is investigated. The procedure was carried out via multicomponent reaction of isothiocyanate, alkyl bromides, N-methylimidazole, and triphenylphosphine in the presence of magnetic iron oxide nanoparticles (Fe3O4-MNPs) as reusable catalyst under solvent-free conditions at 50 degrees C. Also, Fe3O4-MNPs were produced using green synthetic method by reduction of ferric chloride solution with Clover Leaf water extract. The nanoparticles generated using this procedure can potentially be important in different purposes such as organic synthesis. Easy, simple, rapid, and clean procedures for the synthesis of imidazole derivatives are the advantages of this study.

Note that a catalyst decreases the activation energy for both the forward and the reverse reactions and hence accelerates both the forward and the reverse reactions. you can also check out more blogs about 3543-73-5. SDS of cas: 3543-73-5.

Application of 3543-73-5, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 3543-73-5, Name is Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, SMILES is O=C(OCC)CCCC1=NC2=CC(N)=CC=C2N1C, belongs to imidazoles-derivatives compound. In a article, author is Jayabharathi, Jayaraman, introduce new discover of the category.

Binding interaction of bioactive imidazole with bovine serum albumin-A mechanistic investigation

A novel Y-shaped imidazole derivative 4-((E)-2-(4,5-diphenyl-1-p-tolyl-1H-imidazol-2-yl)vinyl)phenol has been synthesized and characterised by IR, UV-vis, mass and NMR spectral techniques. The mutual interaction of this imidazole derivative (DPTIV) with bovine serum albumin (BSA) was investigated using photoluminescent studies. The fluorescence quenching mechanism of BSA by DPTIV was analyzed and the binding constant has been calculated. The binding distance between DPTIV and BSA was obtained based on the theory of Forester’s non-radiation energy transfer. The effect of some common ions on the binding constant between DPTIV and BSA was also examined. (C) 2011 Elsevier B.V. All rights reserved.

Application of 3543-73-5, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 3543-73-5.

In an article, author is Balaji, Kola, once mentioned the application of 3543-73-5, HPLC of Formula: C14H19N3O2, Name is Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, molecular formula is C14H19N3O2, molecular weight is 261.3196, MDL number is MFCD09840909, category is imidazoles-derivatives. Now introduce a scientific discovery about this category.

Ultrasonic Synthesis, Antimicrobial and Brine Shrimp Lethality Assay of Novel Thiadiazole-Imidazole Derivatives

A facile synthesis of 2, 5-disubstituted thiadiazole derivatives has been achieved by mixing and refluxing/ultrasonicating thiosemicarbazide with various aromatic acids in presence of only conc. sulphuric acid, which were further condensed with p-N, N-dimethyl amino / hydroxyl benzaldehyde to get imino derivatives in a sonicator. These characterized compounds were further reacted with ammonium acetate and bromo-isatin to get biological active potential thiadiazole-imidazole analogues. The structures of all newly synthesized compounds were elucidated by various spectral data. All synthesized compounds were evaluated for antimicrobial and few potential compounds were subjected to brine shrimp lethality bioassay. The detailed synthesis, spectroscopic data and activities has been reported

If you are interested in 3543-73-5, you can contact me at any time and look forward to more communication. HPLC of Formula: C14H19N3O2.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 3543-73-5, Name is Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, molecular formula is C14H19N3O2. In an article, author is Hossaini, Zinatossadat,once mentioned of 3543-73-5, HPLC of Formula: C14H19N3O2.

Facile and Efficient Synthesis of New Class of Imidazole Derivatives via One-Pot Multicomponent Reactions in Water

A water-accelerated multicomponent synthesis of organic target molecules has been used as a key method for the preparation of novel imidazole derivatives. The three-component condensation reactions of primary amines with trichloroacetonitrile in the presence of ninhydrine in water are developed as efficient and clean green synthetic procedures for the high-yielding preparation of imidazoles.

Interested yet? Keep reading other articles of 3543-73-5, you can contact me at any time and look forward to more communication. HPLC of Formula: C14H19N3O2.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 3543-73-5, name is Ethyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C14H19N3O2

[0079] To a solution of 81.3 g (650.6 mmol) 2-bromoethanol, 1 g potassium iodide and 100 g water was added 17.0g (65 mmol) compound (6). The reaction mixture was heated to 65-70 C and held at this temperature for 8 h to 12 h.The pH value of the solution was held between 4.2-5.5 during this period by dropwise addition of a solution of 20.0 g(151.4 mmol) diammonium hydrogen phosphate in 35 g water. The control of pH over the duration of the reaction waseffected through use of a pH electrode. The conversion was followed by HPLC. The reaction was continued until thefraction of compound (7A) was ? 1.5 %. Thereby ca. 8% of compound (7B) had formed and the proportion of compound(7) was ca. 87%. The reaction mixture was subsequently concentrated to dryness at ca. 55-60 C under vacuum. Tothe residue was added 150 g water and, preferably with an alkali metal carbonate, the pH value adjusted to ca. 8.5. Thedesired product (7) was extracted with 200 g methylene chloride or 225 g chloroform, and the organic phase subsequentlywashed with 60 – 80 g water. The organic phase was then concentrated to dryness and the remaining oil or alreadycrystalline residue dissolved in 200 g ethyl acetate or alternatively in 60 g actetonitrile. Compound (7) crystallised at ca.5 C and was filtered under suction, washed with 20 g cold ethyl acetate or alternatively with 15 g cold acetonitrile anddried at 60 -70 C. The yield of compound (7) was 18.3 g (52.4 mmol) with a content of ? 98.2% (80.5 % of theory). Thecrude product contained ?0.6% compound (7A) and compound (7B) respectively as well as <0.15% of compound (7C).0082] Analogous to Example 4 but with use of 9.0 g (65 mmol) potassium carbonate dissolved in 12 g water to holdthe pH value between 4.2 - 5.5. Identical results in terms of yield and quality.[0084] This example is a scaled-up analogue of Example 6 with use of 340 g (1.3 mol) compound (6), 2000 ml waterand 1625 g (13 mol) 2-bromoethanol. The reaction was performed without potassium iodide at 69 - 70C.. The pH valuewas held between 4.2 - 5.5 using a solution of 138 g sodium carbonate (1.3 mol) in 500 g water. Until a content ofcompound (7A) of ?1.5% was reached, the duration of the reaction was 13.5 h. The yield of compound (7) was 365 gcrude and 343.5 g after recrystallisation from acetonitrile (75.6% of theory). According to the analysis of related databases, 3543-73-5, the application of this compound in the production field has become more and more popular. Reference:
Patent; HEYL Chemisch-Pharmazeutische Fabrik GmbH und Co. KG; Frey, Michael; Walther, Dirk-Detlef; EP2690096; (2014); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 3543-73-5 as follows. 3543-73-5

[0079] To a solution of 81.3 g (650.6 mmol) 2-bromoethanol, 1 g potassium iodide and 100 g water was added 17.0g (65 mmol) compound (6). The reaction mixture was heated to 65-70 C and held at this temperature for 8 h to 12 h.The pH value of the solution was held between 4.2-5.5 during this period by dropwise addition of a solution of 20.0 g(151.4 mmol) diammonium hydrogen phosphate in 35 g water. The control of pH over the duration of the reaction waseffected through use of a pH electrode. The conversion was followed by HPLC. The reaction was continued until thefraction of compound (7A) was ? 1.5 %. Thereby ca. 8% of compound (7B) had formed and the proportion of compound(7) was ca. 87%. The reaction mixture was subsequently concentrated to dryness at ca. 55-60 C under vacuum. Tothe residue was added 150 g water and, preferably with an alkali metal carbonate, the pH value adjusted to ca. 8.5. Thedesired product (7) was extracted with 200 g methylene chloride or 225 g chloroform, and the organic phase subsequentlywashed with 60 – 80 g water. The organic phase was then concentrated to dryness and the remaining oil or alreadycrystalline residue dissolved in 200 g ethyl acetate or alternatively in 60 g actetonitrile. Compound (7) crystallised at ca.5 C and was filtered under suction, washed with 20 g cold ethyl acetate or alternatively with 15 g cold acetonitrile anddried at 60 -70 C. The yield of compound (7) was 18.3 g (52.4 mmol) with a content of ? 98.2% (80.5 % of theory). Thecrude product contained ?0.6% compound (7A) and compound (7B) respectively as well as 99.2%, wherein compound (7A)was removed below a content of 0.2 % and compound (7B) below 0.3 %. Through the course of the reaction, the contentof compound (7C) was kept below 0.15 %, as this compound can only poorly be removed by recrystallization from theabove described solvents. The overall yield of this step was 76.5% of theory and was thus ca. 12.5% higher than thatdescribed in the procedure using ethylene oxide as according to DD34727 and ca. 31% higher in comparison to thefavoured procedure of W02011079193 involving addition of Huenig?s base.Example 5: Synthesis of ethyl 4-[5-[bis(2-hydroxyethyl)amino]-1-methyl-1H-benzimidazol-

According to the analysis of related databases, 3543-73-5, the application of this compound in the production field has become more and more popular.

Reference:
Patent; HEYL Chemisch-Pharmazeutische Fabrik GmbH und Co. KG; Frey, Michael; Walther, Dirk-Detlef; EP2690096; (2014); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem