Category: 29914-81-6

Electric Literature of 29914-81-6, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 29914-81-6, name is 1,3-Bis(1H-benzo[d]imidazol-2-yl)benzene belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.

c, 2.6 mmol of 1, 14.5 mmol KOH and 2 mL of 1-iodo-n-hexane were dissolved in 30 mL of acetonitrile, refluxed for 24 hours, the solvent was removed to obtain a brown oil, dissolve with chloroform, and extracted and washed with distilled water 9 to 10 times. The filtrate was removed and the obtained brown solution was concentrated to 3 to 5 mL, and subjected to column chromatography with 100 to 200 mesh silica gel as the stationary phase and ethyl acetate as the eluent, Rf of the product was 0.7 to 0.8, to obtain dibenzimidazole phenyl complex 2 (yellow-white solid, yield 93%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,3-Bis(1H-benzo[d]imidazol-2-yl)benzene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Guangzhou Yuxin Intelligent Science And Technology Institute Co., Ltd.; Xi Yanan; Hu Shujin; (19 pag.)CN110950912; (2020); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 29914-81-6, name is 1,3-Bis(1H-benzo[d]imidazol-2-yl)benzene, A new synthetic method of this compound is introduced below., Formula: C20H14N4

General procedure: To 10 mL dry acetone were added [Ru(H2bip)Cl3] (54 mg,0.10 mmol) and AgOTf (96 mg, 0.37 mmol). The mixture wasrefluxed for 2 h before cooling to room temperature. The resultingAgCl precipitate was removed by filtration, and the filtrate wasconcentrated to dryness. To the residue were added ligand Mebib(36.9 mg, 0.11 mmol), DMF (10 mL), and t-BuOH (10 mL). Themixture was then refluxed for 24 h. After cooling to room temperature,the solventwas removed under reduced pressure, and theresiduewas dissolved in a mixture of 10 mL methanol and 1mL 1Maq. HCl. The mixture was then treated with 100 mg KPF6. Theresulting precipitate was collected by filtration and washing withwater and Et2O. The obtained solid was subjected to flash columnchromatography on silica gel (eluent: CH3CN/H2O/aq.KNO3, 100/10/0.2) to give 34.5 mg of 1(PF6)2 in 37% yield.

The synthetic route of 29914-81-6 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Shao, Jiang-Yang; Zhong, Yu-Wu; Journal of Organometallic Chemistry; vol. 845; (2017); p. 144 – 150;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Synthetic Route of 29914-81-6, A common heterocyclic compound, 29914-81-6, name is 1,3-Bis(1H-benzo[d]imidazol-2-yl)benzene, molecular formula is C20H14N4, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

c. Add 2.56 mmol of 1,14.3 mmol KOH and 2 mL of 1-iodo-n-hexane were dissolved in 30 mL of acetonitrile and refluxed for 24 hours. The solvent was removed to obtain a brown oil, which was dissolved in chloroform. Distilled water was extracted and washed 9-10 times, and the filtrate was taken to obtain a brown solution. Concentrated to 3 ~ 5mL, using 100 ~ 200 mesh silica gel as stationary phase, ethyl acetate was used as the eluent for column chromatography. The Rf of the product was 0.7 to 0.8. bisbenzimidazole phenyl complex 2 was obtained (yellow-white solid, yield 89%).

The synthetic route of 29914-81-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Guangzhou Yuxin Intelligent Science And Technology Institute Co., Ltd.; Xi Yanan; Hu Shujin; (17 pag.)CN110590853; (2019); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

These common heterocyclic compound, 29914-81-6, name is 1,3-Bis(1H-benzo[d]imidazol-2-yl)benzene, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. SDS of cas: 29914-81-6

1,3-bis(1H-benzo[d]imidazol-2-yl)benzene (MBImB) was first synthesized according to our earlier report [19]. 10.01 g MBImB was dissolved in anhydrous DMF, and then 3.5 g NaH encapsulated in mineraloil (60%) was added and stirred for 0.5 h. When the NaH reaction was completed, 1-bromopropane (9.0 g) was added. After degassing, the solution was heated at 100 C overnight under nitrogen atmosphere.After cooling, 200 ml water was added, and the aqueous layer was washed with CH2Cl2 (2¡Á30 ml). The combined organic extract was dried over Na2SO4, filtered, and concentrated under high vacuum. The pure product was obtained as a red viscous liquid. Yield, 71%. 1H NMR(300 MHz, CDCl3) delta 8.02 (s, 1 H), 7.90-7.78 (m, 4 H), 7.72-7.65 (m,1 H), 7.44 (dd, J=9.1, 5.1 Hz, 2 H), 7.39-7.29 (m, 4 H), 4.30-4.20(m, 4 H), 1.91-1.77 (m, 4 H), 0.85 (t, J =7.4 Hz, 6 H). ESI-MS m/z:394.1.

The synthetic route of 1,3-Bis(1H-benzo[d]imidazol-2-yl)benzene has been constantly updated, and we look forward to future research findings.

Reference:
Article; Li, Chao-Jie; Yin, Shao-Yun; Wang, Hai-Ping; Wei, Zhang-Wen; Pan, Mei; Journal of Photochemistry and Photobiology A: Chemistry; vol. 379; (2019); p. 99 – 104;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem