Some common heterocyclic compound, 29528-28-7, name is 4-(1H-Imidazol-4-yl)aniline, molecular formula is C9H9N3, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. COA of Formula: C9H9N3
Example 3; (4Z)-4-({[4-(1H-Imidazol-4-yl)phenyl]amino}methylene)-1,4-dihydro-3(2H)-isoquinolinone; A toluene (3 mL) solution containing (4E)-4-[(dimethylamino)methylene]-1,4-dihydro-3(2H)-isoquinolinone (300 mg, 1.48 mmol) and 4-(1H-imidazol-4-yl)aniline (265 mg, 1.66 mmol) is heated at 110 C. for 4 h. Using the same workup as example 1, 0.13 g (28%) orange solid is obtained: mp 151-152 C. (dec.); HRMS (ESI) m/z calcd for C19H16N4O 317.13969, found 317.13894 (M+H)+1.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 29528-28-7, its application will become more common.