Category: 2622-67-5

Zhao, Dongbing published the artcileRegiospecific Synthesis of 1,2-Disubstituted (Hetero)aryl Fused Imidazoles with Tunable Fluorescent Emission, Computed Properties of 2622-67-5, the publication is Organic Letters (2011), 13(24), 6516-6519, database is CAplus and MEDLINE.

A palladium-catalyzed two or fourfold amination was established that allows regiospecific synthesis of a diversity-oriented library of 1,2-disubstituted (hetero)aryl fused imidazoles, e.g., I, and provides an exceptional tool for the discovery of fluorescent scaffolds with tunable fluorescence emission. These fluorophores have been applied as fluorescent probes for live cell imaging.

Organic Letters published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C8H7ClO3, Computed Properties of 2622-67-5.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Muto, Kei published the artcileC-H arylation and alkenylation of imidazoles by nickel catalysis: solvent-accelerated imidazole C-H activation, Application In Synthesis of 2622-67-5, the publication is Chemical Science (2015), 6(12), 6792-6798, database is CAplus and MEDLINE.

The first nickel-catalyzed C-H arylations and alkenylations of imidazoles with phenol and enol derivatives are described. Under the influence of Ni(OTf)₂/dcype/K₃PO₄ (dcype: 1,2-bis(dicyclohexylphosphino)ethane) in t-amyl alc., imidazoles can undergo C-H arylation with phenol derivatives The C-H arylation of imidazoles with chloroarenes as well as that of thiazoles and oxazoles with phenol derivatives can also be achieved with this catalytic system. By changing the ligand to dcypt (3,4-bis(dicyclohexylphosphino)thiophene), enol derivatives could also be employed as coupling partners achieving the C-H alkenylation of imidazoles as well as thiazoles and oxazoles. Thus, a range of C2-arylated and alkenylated azoles can be synthesized using this newly developed nickel-based catalytic system. The key to the success of the C-H coupling of imidazoles is the use of a tertiary alc. as solvent. This also allows the use of an air-stable nickel(II) salt as the catalyst precursor.

Chemical Science published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, Application In Synthesis of 2622-67-5.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Alonso, Jorge published the artcileA Direct, Regioselective Palladium-Catalyzed Synthesis of N-Substituted Benzimidazoles and Imidazopyridines, Product Details of C19H14N2, the publication is European Journal of Organic Chemistry (2011), 234-237, S234/1-S234/9, database is CAplus.

Unsym., N-substituted benzimidazoles and imidazopyridines can be prepared directly from 2-halonitroarenes and amides through Pd(TFA)₂/(R)-BINAP-catalyzed cross-coupling and subsequent reductive aminocyclization. This sequence can be conducted by a one-pot procedure. The method is versatile and allows the straightforward, regioselective preparation of these important nitrogen heterocycles.

European Journal of Organic Chemistry published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, Product Details of C19H14N2.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Peng, Xiao-Chong published the artcileActivated carbon supported hafnium(IV) chloride as an efficient, recyclable, and facile removable catalyst for expeditious parallel synthesis of benzimidazoles, Application of 1,2-Diphenyl-1H-benzo[d]imidazole, the publication is Catalysts (2020), 10(4), 436, database is CAplus.

A highly efficient method for parallel synthesis of a diversity of 1,2-disubstituted benzimidazoles from N-substituted phenylenediamines and aldehydes has been developed by using 10 mol% HfCl₄ on activated carbon (HfCl₄/C) as the catalyst. The newly reported HfCl₄/C catalyst not only mediated fast and clean formation of benzimidazoles but also could be easily removed from the reaction solution and reused up to eight times. Scanning electron microscope (SEM) and thermal desorption studies showed that activated carbon could reversibly adsorb and release Hf(IV) in ethanol upon cooling and heating, thereby serving as a thermal-controlled solid support.

Catalysts published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, Application of 1,2-Diphenyl-1H-benzo[d]imidazole.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Luo, Ching-Zong published the artcileRh^III-catalyzed C-H activation: a versatile route towards various polycyclic pyridinium salts, Quality Control of 2622-67-5, the publication is Chemistry – A European Journal (2013), 19(42), 14181-14186, database is CAplus and MEDLINE.

An efficient and convenient method for the synthesis of highly substituted polycyclic pyridinium salts from the reaction of various 2-aryl-pyridines and 2-aryl-sp²-nitrogen-atom-containing heterocycles with alkynes through rhodium(III)-catalyzed C-H activation and annulation under an O₂ atmosphere is described. A possible mechanism that involves the chelation-assisted C-H activation of the 2-aryl-pyridine substrate, insertion of the alkyne, and reductive elimination is proposed. This mechanism was supported by the isolation of a five-membered rhodacycle (I’). In addition, kinetic isotope studies were performed to understand the intimate reaction mechanism.

Chemistry – A European Journal published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, Quality Control of 2622-67-5.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem

Luo, Ching-Zong published the artcileRh^III-catalyzed C-H activation: a versatile route towards various polycyclic pyridinium salts, Quality Control of 2622-67-5, the publication is Chemistry – A European Journal (2013), 19(42), 14181-14186, database is CAplus and MEDLINE.

An efficient and convenient method for the synthesis of highly substituted polycyclic pyridinium salts from the reaction of various 2-aryl-pyridines and 2-aryl-sp²-nitrogen-atom-containing heterocycles with alkynes through rhodium(III)-catalyzed C-H activation and annulation under an O₂ atmosphere is described. A possible mechanism that involves the chelation-assisted C-H activation of the 2-aryl-pyridine substrate, insertion of the alkyne, and reductive elimination is proposed. This mechanism was supported by the isolation of a five-membered rhodacycle (I’). In addition, kinetic isotope studies were performed to understand the intimate reaction mechanism.

Chemistry – A European Journal published new progress about 2622-67-5. 2622-67-5 belongs to imidazoles-derivatives, auxiliary class Benzimidazole,Benzene,Benzimidazole, name is 1,2-Diphenyl-1H-benzo[d]imidazole, and the molecular formula is C19H14N2, Quality Control of 2622-67-5.

Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem