Category: 25045-82-3

Palladium-catalyzed C3-selective C-H oxidative carbonylation of imidazo[1,2-a]pyridines with CO and alcohols: a way to access esters was written by Wang, Shoucai;Zhang, Siyu;Liu, Meichen;Zang, Jiawang;Jiang, Guangbin;Ji, Fanghua. And the article was included in Organic Chemistry Frontiers in 2020.Category: imidazoles-derivatives This article mentions the following:

A palladium-catalyzed C3-selective C-H oxidative carbonylation for the synthesis of various esters such as I [R¹ = H, Ph, 2-thienyl, etc.; R² = H, 8-Me, 7-CN, etc.; R³ = Me, Et, Bn, etc.] from imidazo[1,2-a]pyridines, CO and alcs. with high efficiency and high atom economy was developed. This process featured excellent functional-group tolerance and was safely conducted on a gram scale. This reaction also facilitated the convenient synthesis of clin. used saripidem. Moreover, several natural products such as leaf alc., phytol, nerol and tetrahydrogeraniol were well tolerated, delivering the desired products in good to excellent yields. In the experiment, the researchers used many compounds, for example, 6-Nitroimidazo[1,2-a]pyridine (cas: 25045-82-3Category: imidazoles-derivatives).

6-Nitroimidazo[1,2-a]pyridine (cas: 25045-82-3) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Category: imidazoles-derivatives

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Principal fragmentations of mono-, di-, tri-, and tetraazaindolizines under electron impact was written by Daunis, Jacques;Lopez, Helene;Maury, Georges. And the article was included in Organic Mass Spectrometry in 1977.Application In Synthesis of 6-Nitroimidazo[1,2-a]pyridine This article mentions the following:

The principal fragmentations of ¹H azaindolizines containing the imidazo[1,2-a]pyridine, -[1,5-a]pyrimidine and -[1,5-b]-1,2,4-triazine and triazolo[2,3–b]-, -[4,3-b]-, -[3,4-c]- and -[3,2-c]-1,2,4-triazine structures are described. Each structure has an individual fragmentation path except where Dimroth rearrangement to an isomeric product occurs. The degradation scheme was correlated with the number and position of the N atoms. In the experiment, the researchers used many compounds, for example, 6-Nitroimidazo[1,2-a]pyridine (cas: 25045-82-3Application In Synthesis of 6-Nitroimidazo[1,2-a]pyridine).

6-Nitroimidazo[1,2-a]pyridine (cas: 25045-82-3) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Many drugs contain an imidazole ring, such as certain antifungal drugs, the nitroimidazole series of antibiotics, and the sedative midazolam.Application In Synthesis of 6-Nitroimidazo[1,2-a]pyridine

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem