24134-26-7 Archives - Imidazoles-derivatives

Kravchenko, D. V. et al. published their research in Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya in 2005 | CAS: 24134-26-7

2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole (cas: 24134-26-7) belongs to imidazole derivatives. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole has become an important synthon in the development of new drugs. Imidazole based anticancer drug find applications in cancer chemotherapy. It is used as buffer component for purification of the histidine tagged recombinant proteins in immobilized metal-affinity chromatography (IMAC).COA of Formula: C9H9N3

Synthesis of substituted 4-oxo-7-sulfamoyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepines was written by Kravchenko, D. V.;Ivanovskii, S. A.;Korsakov, M. K.;Dorogov, M. V.;Tkachenko, S. E.;AsHchenko, A. V.. And the article was included in Izvestiya Vysshikh Uchebnykh Zavedenii, Khimiya i Khimicheskaya Tekhnologiya in 2005.COA of Formula: C9H9N3 This article mentions the following:

A combinatorial library of substituted 4-oxo-7-sulfamoyl-2,3,4,5-tetrahydrobenzo[b][1,4]thiazepines was synthesized via chlorosulfonylation of tetrahydrobenzothiazepinones followed by reaction with a range of primary and secondary amines. Physicochem. parameters of some of the products, such as lipophilicity, number of rotating bonds and number of hydrogen bond donors and acceptors have been calculated In the experiment, the researchers used many compounds, for example, 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole (cas: 24134-26-7COA of Formula: C9H9N3).

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Grigor’ev, V. P. et al. published their research in Protection of Metals (Translation of Zashchita Metallov) in 2002 | CAS: 24134-26-7

2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole (cas: 24134-26-7) belongs to imidazole derivatives. 1H-imidazole is an imidazole tautomer which has the migrating hydrogen at position 1. It is a conjugate base of an imidazolium cation. It is a conjugate acid of an imidazolide. It is a tautomer of a 4H-imidazole. Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division.Electric Literature of C9H9N3

Dependence of the protective properties of mixtures based on several reaction series on the number and concentrations of the components was written by Grigor’ev, V. P.;Shpan’ko, S. P.;Nassar, A. F.;Anisimova, V. A.. And the article was included in Protection of Metals (Translation of Zashchita Metallov) in 2002.Electric Literature of C9H9N3 This article mentions the following:

Mixtures based on azomethine, imidazobenzoimidazole, and pyrimidobenzoimidazole derivatives were tested as inhibitors of iron corrosion in 1 M H₂SO₄ in the presence of 0.25 mol/l NaCl. The number and concentrations of their components were varied with the aim of studying their influence on the protection effects of the mixtures The resulting exptl. dependences, of the protective effectiveness on the number and concentration of the components, as well as the polar properties of substituents in their mols., can be interpreted in terms of the linear Gibbs energy relation (LGER). This conclusion is valid over a wide range of medium temperatures (20-60°C), provided the volume concentrations of compounds in each reaction series are kept constant In the experiment, the researchers used many compounds, for example, 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole (cas: 24134-26-7Electric Literature of C9H9N3).

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

S-21 News Analyzing the synthesis route of 24134-26-7

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 24134-26-7, name is 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole, A new synthetic method of this compound is introduced below., Quality Control of 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole

General procedure: A solution of 2 mmol of compound 1-3 and 2.1 mmol of BrCH2C6H4C6H4R-o or ethyl 4-(bromomethyl)benzoate in 10 ml of CH3NO2 was boiled for 7.5 h. The reaction mixture was cooled and left for two days at 5 C. The precipitated hydrobromide was filtered and washed with acetone.

Reference:
Article; Babkov, Denis A.; Zhukowskaya, Olga N.; Borisov, Alexander V.; Babkova, Valentina A.; Sokolova, Elena V.; Brigadirova, Anastasia A.; Litvinov, Roman A.; Kolodina, Alexandra A.; Morkovnik, Anatolii S.; Sochnev, Vadim S.; Borodkin, Gennady S.; Spasov, Alexander A.; Bioorganic and Medicinal Chemistry Letters; vol. 29; 17; (2019); p. 2443 – 2447;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Analyzing the synthesis route of C9H9N3

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 24134-26-7, name is 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole, A new synthetic method of this compound is introduced below., Safety of 2,3-Dihydro-1H-benzo[d]imidazo[1,2-a]imidazole