Discovery of 1-Octyl-1H-imidazole

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Related Products of 21252-69-7, A common heterocyclic compound, 21252-69-7, name is 1-Octyl-1H-imidazole, molecular formula is C11H20N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Synthesis of 1-octyl-3(propyl-3-sulfonyl) imidazolium 1 equivalent of 1 -octyl-imidazole was reacted with 1 equivalent of propanesultone at reflux temperature in 10percent toluene as solvent. After 10 hours, the mixture was cooled down at room temperature and then filtrated. The cake was washed with 3 portions of toluene before drying under high vacuum at 60°C.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; ECOLE D’INGENIEURS ET D’ARCHITECTES DE FRIBOURG; MARTI, Roger; VANOLI, Ennio; AEBY, Sandrine; FISCHER, Fabian; HAPPE, Manuel; WO2013/8172; (2013); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Some tips on 21252-69-7

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Octyl-1H-imidazole, other downstream synthetic routes, hurry up and to see.

Application of 21252-69-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 21252-69-7, name is 1-Octyl-1H-imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.

In einen 2 I Schlenkkolben werden 830,5 g (5 mol) 1-Octylimidazol vorgelegt und 630,5g (5 mol) Dimethylsulfat portionsweise zugegeben. Der Ansatz wird danach 15 Minuten nachgeruehrt. Der Kolbeninhalt wird danach in ein 5I Becherglas ueberfuehrt und zu einer Mischung von 548,0g (5 mol) Natriumtetrafluoroborat in 2 Liter Wasser gegeben. Sofort bildetsich das Produkt als zweite, fluessige Phase. . Nach einer Phasentrennung wird die waessrige Phase noch einmal mit 1 Liter CH2Cl2extrahiert, und das organische Extrakt von Methylenchlorid befreit. Beide Produktfraktionen werden vereinigt und ueber Nacht bei 60°C am HV getrocknet. Man erhaelt 1-Octyl-3-methylimidazoliumtetrafluoroborat in 94 percentiger Ausbeute. Zum qualitativen Nachweis auf Chloridreste, werden ca. 1 ml des Produktes mit ca. 5 ml Wasser versetzt und mit 2 Tropfen konzentrierter Salpetersaeure angesaeuert. Zu dieser Loesung werden dann ca. 3-4 Tropfen Silbernitrat gegeben um etwaig vorhandenes Chlorid als Silberchlorid auszufaellen. Das Ausbleiben eines Silberchlorid-Niederschlags spricht fuer die komplette Abwesenheit von Chloridresten. [26.1] 1H-NMR (300 MHz, CDCl3):delta=9.3 ppm (s,1H,Ha); delta=7.26 ppm (d,1H,Hc); delta=7.24 ppm (d,1H,Hd); delta=4.1 ppm (t,2H,He); delta=3.9 ppm (s,2H,Hb); delta=1.6 ppm (m,2H,Hf); delta=1.2 ppm (m,10H,Hg,h,i,j,k); delta=0.8 ppm (t,3H,HI).13C-NMR (75 MHz, CDCl3):delta=137 ppm (C1); delta=124-122 ppm (C3,C4); delta=48 ppm (C5); delta=35 ppm (C2); delta=29-24 ppm (C6-C10); delta=20 ppm (C11); delta=13 ppm (C12).19F-NMR (281 MHz, CDCl3):delta= -151,3 ppm (d, 1J(BF)= 22 Hz)

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Octyl-1H-imidazole, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Solvent Innovation GmbH; EP1182196; (2002); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The important role of 1-Octyl-1H-imidazole

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Octyl-1H-imidazole, other downstream synthetic routes, hurry up and to see.

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1,6-Dibromohexane (10.00 g, 42 mmol) was dissolved in anhydrous acetonitrile (10 mL) and introduced into a three-neck round-bottom flask. After the solution was heated gently to reflux, a solution of 1 (0.50 g, 2.80 mmol) in anhydrous acetonitrile (5 mL) was added dropwise under N2 atmosphere. The reaction mixture was stirred for 24 h at reflux and then cooled to room temperature. The solvent was removed to give a residue, which was purified by washing with anhydrous diethyl ether (35 mL), and concentrated under reduced pressure. The residue was dried under vacuum to afford 2 as a puce oil (1.01 g,85 percent). deltaH (CDCl3, 400 MHz) 10.32 (1H, s), 7.62 (1H, s), 7.50 (1H, s), 4.40 (2H, t, J 7.2), 4.34 (2H, t, J 7.6), 3.43?3.40 (4H, m), 2.03?1.84 (6H, m), 1.51?1.23 (12H, m), 0.87 (3H, t, J 6.8). deltaC (CDCl3, 100 MHz) 136.3, 122.1, 121.8, 49.9, 49.6, 33.7, 32.3,32.1, 31.5, 30.1, 30.0, 28.9, 27.2, 26.1, 25.1, 22.4, 14.0. m/z (ESI) 345 ([M]+). m/z 345.1733. HRMS (ESI) Anal. Calc. for C17H32BrN2 ([M]+) 345.1728.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Octyl-1H-imidazole, other downstream synthetic routes, hurry up and to see.

Share a compound : 1-Octyl-1H-imidazole

The synthetic route of 1-Octyl-1H-imidazole has been constantly updated, and we look forward to future research findings.

Application of 21252-69-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 21252-69-7, name is 1-Octyl-1H-imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.

General procedure: 1,2-Dimethyl imidazole (9.61 g; 0.10 mol) and trimethylphosphate (14.01 g; 0.10 mol) were mixed at room temperature under argon and vigorous stirring, then heated to 80°C and stirred at this temperature for 1h. Acetonitrile (20 mL) was added and the mixture was stirred at 80°C for 23h. The mixture was left at room temperature, the precipitate was separated,washed twice with acetonitrile and dried under vacuum (2 Torr) for 4 h at 80°C.

The synthetic route of 1-Octyl-1H-imidazole has been constantly updated, and we look forward to future research findings.

Extended knowledge of 21252-69-7

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1-Octyl-1H-imidazole, its application will become more common.

Application of 21252-69-7,Some common heterocyclic compound, 21252-69-7, name is 1-Octyl-1H-imidazole, molecular formula is C11H20N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: A solution of 1,3-dibromo-2-propyl glycoside 2 (1 mmol) and thealkylated imidazole 3 (6 mmol) in xylene (2 mL) was heated to 125 ¡ãC for 2 h. The solvent was evaporated before the crude product wastaken up in MeCN (10 mL) and extracted 4 times with hexane (60 mL) to remove remaining imidazole 3. The acetonitrile phase was concentrated under reduced pressure to provide the desired product 4 as pale yellow syrup in yields higher than 90percent.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1-Octyl-1H-imidazole, its application will become more common.

Reference:
Article; Salman, Abbas Abdulameer; Goh, Ean Wai; Heidelberg, Thorsten; Hussen, Rusnah Syahila Duali; Ali, Hapipah Mohd; Journal of Molecular Liquids; vol. 222; (2016); p. 609 – 613;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

New downstream synthetic route of 21252-69-7

The synthetic route of 21252-69-7 has been constantly updated, and we look forward to future research findings.

Reference of 21252-69-7,Some common heterocyclic compound, 21252-69-7, name is 1-Octyl-1H-imidazole, molecular formula is C11H20N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Silver(I)-N-octylimidazole complexes were alsosynthesized using a previously reported method with a minor modification. Typically, N-octylimidazole (2 mol equiv.) was added to a solution of AgNO3 (1 mol equiv.) in ethanol (15 mE) and the reaction mixture was stirred at room temperature for 24 h. The reaction mixture was filtered and evaporation of the solvent mixture gave a brown oil or cream solid. The brown oil was re-dissolved in dichloromethane and extracted three times with watet The organic phase was dried on anhydrous sodium sulfate and the solvent was removed under reduced pressure. Other silver(I)-N-alkylimidazole complexes were synthesized in the same manner. The solid complexes were further purified by recrystallization by dissolving in dichloromethane and precipitated with hexane.

The synthetic route of 21252-69-7 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Kleyi, Phumelele; Maity, Arjun; Ray, Suprakas Sinha; (16 pag.)US2018/255777; (2018); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem