In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 19213-72-0 as follows. SDS of cas: 19213-72-0
SYNTHESIS EXAMPLE 9 Synthesis of 4(5)-Chloro-5(4)-phenylimidazole-2-carboxylic acid (Compound No. 15) 2.5 g of 4(5)-chloro-2-(ethoxycarbonyl)-5(4)-phenylimidazole (Compound No. 5) was added to 50 ml of a 5% aqueous sodium hydroxide solution, and the mixture was reacted at the reflux temperature for one hour to obtain a reaction mixture including sodium 4(5)-chloro-5(4)-phenylimidazole-2-carboxylate. The reaction mixture was poured into ice water and neutralized with hydrochloric acid. A precipitated crystal was separated by filtration and washed with water to obtain 4(5)-chloro-5(4)-phenylimidazole-2-carboxylic acid (Compound No. 15) having a melting point of 158 to 160 C.
According to the analysis of related databases, 19213-72-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Ishihara Sangyo Kaisha Ltd.; US5023336; (1991); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem