Category: 16961-25-4

SDS of cas: 16961-25-4. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: Hydrogen tetrachloroaurate(III) trihydrate, is researched, Molecular AuCl4H7O3, CAS is 16961-25-4, about Extracellular vesicles based self-grown gold nanopopcorn for combinatorial chemo-photothermal therapy. Author is Zhang, Dan; Qin, Xianya; Wu, Tingting; Qiao, Qi; Song, Qingle; Zhang, Zhiping.

Here, we generated a popcorn-like gold nanostructure exploiting extracellular vesicles (EVs). EVs can first serve as the vehicle for chemotherapeutic drug doxorubicin (DOX). Taking advantages of EVs, gold nanoparticles can be then self-grown surrounding the EVs, assembling into popcorn-like nanostructure. The formulated nanopopcorn, consisting of self-grown gold nanoparticles and EVs encapsulated with DOX, retained the photothermal transduction from gold nanoparticle assemblies and cytotoxicity of DOX. Under external near IR irradiation, gold nanopopcorn can produce hyperthermia to induce tumor ablation and trigger drug release, achieving combinatorial chemo-photothermal therapy. The nanoplatform demonstrated improved cellular internalization, controlled drug release, enhanced antitumor efficacy with tumor inhibitory rate up to 98.6% and reduced side effects. Our design of popcorn-like nanostructure will contribute a novel modality for facile and green synthesis of complex metal nanostructures exploiting natural properties of EVs for combinational therapy.

The article 《Extracellular vesicles based self-grown gold nanopopcorn for combinatorial chemo-photothermal therapy》 also mentions many details about this compound(16961-25-4)SDS of cas: 16961-25-4, you can pay attention to it or contacet with the author([email protected]) to get more information.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Ultrasensitive inkjet-printed based SERS sensor combining a high-performance gold nanosphere ink and hydrophobic paper》. Authors are Godoy, N. V.; Garcia-Lojo, D.; Sigoli, F. A.; Perez-Juste, J.; Pastoriza-Santos, I.; Mazali, I. O..The article about the compound:Hydrogen tetrachloroaurate(III) trihydratecas:16961-25-4,SMILESS:Cl[Au-](Cl)(Cl)Cl.[H]O[H].[H]O[H].[H]O[H].[H+]).Category: imidazoles-derivatives. Through the article, more information about this compound (cas:16961-25-4) is conveyed.

We report the fabrication of a low-cost paper-based SERS platform with enhanced sensing capabilities. The sensor consists of a highly concentrated glycerol/ethanol dispersion of ca. 77 nm Au nanospheres (AuSph) inkjet-printed on hydrophobic chromatog. paper forming circular sensing spots of 1 mm in diameter The AuSph ink exhibits high stability for 1 yr. Interestingly, we demonstrate that the modification of the paper surface with hydrophobic ligands improve the sensing capabilities by confining the analyte solution in the AuSph sensing platform. It contributes to both concentrate the analyte, as well as, to decrease the sample volume to just a few μl. We also analyze the effect of the amount of the nanoparticles, tunable by the number of printing cycles, in the SERS performance of the plasmonic spots. The results show that 5 printing cycles give rise to sensing platforms with great SERS response in terms of intensity and uniformity. The spot-to-spot reproducibility is also analyzed observing good results even for AuSph spots from different printed papers. The paper-based SERS platform was tested towards the detection of crystal violet (CV) and the fungicide thiram. Addnl., applying a digital protocol for SERS anal., a good linear correlation between the digital counts (or pos. events) and the analyte concentration was obtained at the single-mol. SERS regime. In both cases, the quantification region threshold was 10-11 M. The great sensitivity performance of the inkjet-printed SERS substrate is reflected by the low sample volume needed (only 2μL). The inkjet-printed SERS substrate and the fabrication method demonstrated to be efficient, reliable, reproducible and robust, with a cost less than $ 0.01 per spot.

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Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Plasma Science & Technology (Bristol, United Kingdom) called Visualization of gold nanoparticles formation in DC plasma-liquid systems, Author is Liu, Zhaoyuan; Chen, Qiang; Liu, Qinghuo; Ostrikov, Kostya, which mentions a compound: 16961-25-4, SMILESS is Cl[Au-](Cl)(Cl)Cl.[H]O[H].[H]O[H].[H]O[H].[H+], Molecular AuCl4H7O3, Formula: AuCl4H7O3.

Dual argon plasmas ignited by one d.c. power source are used to treat an aqueous solution of hydrogen tetrachloroaurate-(III) trihydrate (HAuCl4 ·3H2O) which is contained in an H-type electrochem. cell. The solution contained in one cell acts as a cathode, and in the other as an anode. Experiments are carried out to directly visualize the formation process of gold nanoparticles (AuNPs) in separated cells of the H-type electrochem. reactor. The results and analyzes suggest that hydrogen peroxide and hydrated electrons generated from the plasma-liquid interactions play the roles of reductants in the solutions, resp. Hydrogen peroxide can be generated in the case of the liquid being a cathode or an anode, while most of hydrated electrons are formed in the case of the liquid being an anode. Therefore, the reduction of the AuCl-4 ions is mostly attributed to the hydrogen peroxide as the liquid acts as a cathode, while to the hydrogen peroxide and hydrated electrons as the liquid acts as an anode. Moreover, the pH value of the solution can be used to tune the formation processes and the final form of the AuNPs due to its mediation of reductants.

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Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: Hydrogen tetrachloroaurate(III) trihydrate, is researched, Molecular AuCl4H7O3, CAS is 16961-25-4, about Anisotropic Bimetallic Core-Satellite-Poly(aniline) Nanohybrids for Detection of Autoantibodies.Name: Hydrogen tetrachloroaurate(III) trihydrate.

Bimetallic core-satellite nanoparticles are widely exploited in surface-enhanced Raman scattering (SERS)-based applications due to their enhanced optical properties compared to single-component metallic nanoparticles (MNPs). In addition, anisotropic hybrid nanostructures containing both MNPs and polymeric compartments constitute a new class of functional nanomaterials for photonic applications because they show different functionalities and physicochem. characteristics at two distinct compartments. Herein, synthesis of two kinds of anisotropic bimetallic core-satellite-poly(aniline) nanohybrids (ABCPNs) using small or polymeric ligand-coated gold nanospheres or gold nanorods as seeds is reported. The ABCPNs exhibit enhanced optical properties due to a local electromagnetic field generated in the narrow interparticle gap between core and satellite nanoparticles. Furthermore, a SERS-based quant. anal. of autoantibodies against cyclic citrullinated peptide using the ABCPNs as SERS nanoprobes for a diagnosis of early rheumatoid arthritis is demonstrated, suggesting that these multi-functional nanostructures will be potential for advanced SERS-based biosensors.

The article 《Anisotropic Bimetallic Core-Satellite-Poly(aniline) Nanohybrids for Detection of Autoantibodies》 also mentions many details about this compound(16961-25-4)Name: Hydrogen tetrachloroaurate(III) trihydrate, you can pay attention to it, because details determine success or failure

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Radiosensitization by gold nanoparticles: impact of the size, dose rate, and photon energy, published in 2020, which mentions a compound: 16961-25-4, Name is Hydrogen tetrachloroaurate(III) trihydrate, Molecular AuCl4H7O3, Electric Literature of AuCl4H7O3.

Gold nanoparticles (GNPs) emerged as promising antitumor radiosensitizers. However, the complex dependence of GNPs radiosensitization on the irradiation conditions remains unclear. In the present study, we investigated the impacts of the dose rate and photon energy on damage of the pBR322 plasmid DNA exposed to X-rays in the presence of 12 nm, 15 nm, 21 nm, and 26 nm GNPs. The greatest radiosensitization was observed for 26 nm GNPs. The sensitizer enhancement ratio (SER) 2.74 ± 0.61 was observed at 200 kVp with 2.4 mg/mL GNPs. Reduction of X-ray tube voltage to 150 and 100 kVp led to a smaller effect. We demonstrate for the first time that the change of the dose rate differentially influences on radiosensitization by GNPs of various sizes. For 12 nm, an increase in the dose rate from 0.2 to 2.1 Gy/min led to a ∼1.13-fold increase in radiosensitization. No differences in the effect of 15 nm GNPs was found within the 0.85-2.1 Gy/min range. For 21 nm and 26 nm GNPs, an enhanced radiosensitization was observed along with the decreased dose rate from 2.1 to 0.2 Gy/min. Thus, GNPs are an effective tool for increasing the efficacy of orthovoltage X-ray exposure. However, careful selection of irradiation conditions is a key prerequisite for optimal radiosensitization efficacy.

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Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

SDS of cas: 16961-25-4. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: Hydrogen tetrachloroaurate(III) trihydrate, is researched, Molecular AuCl4H7O3, CAS is 16961-25-4, about Femtosecond laser modification of the optical properties of glass containing noble-metal nanoparticles. Author is Nikov, Ro; Nedyalkov, N.; Koleva, M.; Stankova, N.; Iordanova, E.; Yankov, G.; Aleksandrov, L.; Iordanova, R..

The paper presents results on femtosecond laser irradiation-induced modification of the optical properties of a composite material – gold nanoparticles embedded into a borosilicate glass host. The process is initiated by laser pulses delivered by a Ti:sapphire laser system with pulse duration of 35 fs. The glass samples are prepared by melt quenching with gold added as hydrogen tetrachloroaurate (III) hydrate to the initial composition Post-fabrication annealing leads to a homogeneous formation of nanoparticles in the glass; varying the annealing parameters results in producing nanoparticles with different sizes and shapes. The laser irradiation of the samples induces significant modification of the optical spectra of the glass through changes of the nanoparticles characteristics. The effects are studied of the laser fluence, laser wavelength and laser pulses number The heat diffusion equation is applied to estimate the temperature evolution and explain the modifications observed The results demonstrate this technique′s efficiency in modifying the nanoparticles properties with a high 3D spatial resolution, which can be useful in fabrication of integrated optical systems.

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Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Tie, Leopold; Raileanu, Mina; Bacalum, Mihaela; Codita, Irina; Negrea, Stefania Madalina; Caracoti, Costin Stefan; Dragulescu, Elena-Carmina; Campu, Andreea; Astilean, Simion; Focsan, Monica published the article 《Versatile polypeptide-functionalized plasmonic paper as synergistic biocompatible and antimicrobial nanoplatform》. Keywords: polypeptide plasmonic paper synergistic biocompatible antimicrobial nanoplatform; Escherichia coli; Staphylococcus aureus; antimicrobial activity; antimicrobial peptides; biocompatibility; gold nanospheres; paper platform.They researched the compound: Hydrogen tetrachloroaurate(III) trihydrate( cas:16961-25-4 ).Reference of Hydrogen tetrachloroaurate(III) trihydrate. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:16961-25-4) here.

Nowadays, thanks to nanotechnol. progress, which itself guides us more and more closely toward not only the efficient design of innovative nanomaterials or nanostructures, but to the improvement of their functionality, we benefit from an important asset in the battle against pathogenic illnesses. Herein, we report a versatile biocompatible plasmonic nanoplatform based on a Whatman paper incorporating pos.-charged gold nanospherical particles via the immersion approach. The morphol. characterization of the as-engineered-plasmonic paper was examined by SEM (SEM) and HRTEM (high-resolution transmission electron microscopy) investigations, while its surface chem. modification with a synthetic polypeptide, specifically RRWHRWWRR-NH2 (P2), was proved by monitoring the plasmonic response of loaded gold nanospheres and the emission signal of P2 via fluorescence spectroscopy. The as-functionalized plasmonic paper is non-cytotoxic towards BJ fibroblast human cells at bactericidal concentrations Finally, the antimicrobial activity of the P2-functionalized plasmonic paper on both planktonic bacteria and biofilms was tested against two reference strains: Gram-pos. Bacteria, i.e., Staphylococcus aureus and the Gram-neg. Bacteria, i.e., Escherichia coli, determining microbial inhibition of up to 100% for planktonic bacteria. In line with the above presented nanoplatform proper design, followed by their functionalization with active antimicrobial peptides, new roads can be open for determining antibiotic-free treatments against different relevant pathogens.

After consulting a lot of data, we found that this compound(16961-25-4)Reference of Hydrogen tetrachloroaurate(III) trihydrate can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called New Insights on the Dynamic Role of the Protecting Agent on the Reactivity of Supported Gold Nanoparticles, published in 2020, which mentions a compound: 16961-25-4, Name is Hydrogen tetrachloroaurate(III) trihydrate, Molecular AuCl4H7O3, Recommanded Product: Hydrogen tetrachloroaurate(III) trihydrate.

A very efficient catalyst (AuCePVA) was prepared by depositing gold colloids on CeO2 and using polyvinyl alc. (PVA) as protective agent. Complete conversion and selectivity in furfural (2-FA) oxidative esterification to methyl-2-furoate (Me-2-F) was obtained without base under conventional heating at 120°C. AuCePVA was compared with Au/CeO2 obtained by deposition-precipitation method, pointing out that along with the size of the Au nanoparticles and the surface sites of the ceria support, also PVA chains played a role during reaction. In situ FTIR spectroscopy measurements of adsorbed mols. at controlled temperature and pressure demonstrated that PVA acted not merely as gold stabilizer, but also as mediator during the 2-FA oxidative esterification, leaving both Au and ceria sites available for catalysis at the reaction temperature In a perspective of process intensification, the microwave-assisted (MW-assisted) 2-FA oxidative esterification was carried out. Depending on the reaction time and temperature, AuCePVA favored the oxidation of the hemiacetal into the ester rather than the re-oxidation of the acetal into the ester, due to the formation of Ce3+ sites under MW irradiation

After consulting a lot of data, we found that this compound(16961-25-4)Recommanded Product: Hydrogen tetrachloroaurate(III) trihydrate can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Computed Properties of AuCl4H7O3. So far, in addition to halogen atoms, other non-metallic atoms can become part of the aromatic heterocycle, and the target ring system is still aromatic. Compound: Hydrogen tetrachloroaurate(III) trihydrate, is researched, Molecular AuCl4H7O3, CAS is 16961-25-4, about A “”signal off”” aptasensor based on NiFe2O4 NTs and Au@Pt NRs for the detection of deoxynivalenol via voltammetry.

A “”signal off”” aptasensor has been developed to detect deoxynivalenol (DON). DON aptamers (Apt) were used as biol. recognition elements, nickel ferrite nanotubes (NiFe2O4 NTs) are used as the base material to increase the surface area of the electrode, and the Au@Pt NRs were used as carriers for loading signal labels thionine (Thi) and complementary strand (cDNA). In the presence of DON it will be specifically captured by Apt, then the competition mechanism was triggered; the signal mols. fall off from the electrode surface, which then causes the electrode signal to decrease. NiFe2O4 NTs and Au@Pt NRs were characterized by transmission electron microscope (TEM), scanning electron micrograph (SEM), energy-dispersive X-ray spectroscopy (EDS), and X-ray diffraction (XRD). The designed sensor provides a concentration range of 1 x 10-8 to 5 x 10-4 mg mL-1 and limit of detection of 3.02 x 10-9 mg mL-1. Determination of DON in corn meal samples was investigated and the recovery was 98.4 to 103.5%. The proposed aptasensor displayed good sensitivity, high specificity, and acceptable reproducibility. Graphical abstractBased on NiFe2O4 NTs as substrate material and Au@Pt NRs as signal label prepared DON aptasensor for the determination of DON.

After consulting a lot of data, we found that this compound(16961-25-4)Computed Properties of AuCl4H7O3 can be used in many types of reactions. And in most cases, this compound has more advantages.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 16961-25-4, is researched, SMILESS is Cl[Au-](Cl)(Cl)Cl.[H]O[H].[H]O[H].[H]O[H].[H+], Molecular AuCl4H7O3Journal, Evaluation Study, Article, Journal of Agricultural and Food Chemistry called Competitive lateral flow immunoassay relying on Au-SiO2 Janus nanoparticles with an asymmetric structure and function for furazolidone residue monitoring, Author is Su, Lihong; Wang, Lulu; Xu, Jingke; Wang, Zonghan; Yao, Xiaolin; Sun, Jing; Wang, Jianlong; Zhang, Daohong, the main research direction is lateral flow immunoassay gold silica Janus nanoparticle furazolidone; food safety antibiotic residue lateral flow immunoassay; Au−SiO2 Janus nanoparticle; asymmetric structure; furazolidone; lateral flow immunoassay.Name: Hydrogen tetrachloroaurate(III) trihydrate.

Gold nanoparticles (AuNPs) are the most commonly used signal materials in lateral flow immunoassay (LFIA). However, the assay sensitivity of traditional AuNP-based LFIA is usually limited by the incomplete competition between free target analytes and immobilized antigens for the binding of AuNP-labeled antibodies. To unfreeze this limitation, here, asym. Au-SiO2 Janus NPs (about 66 nm) were designed and synthesized. Au-SiO2 Janus NPs can assemble into snowman-like anisotropic structures and combine two different physicochem. properties at their opposite sides, where the AuNP side mainly possesses the antibody conjugating and signal providing functions and the SiO2 side primarily offers the stable function. In virtue of the unique asym. nanostructure, only the AuNP side can interact with target analytes by specific antigen-antibody interactions, which could significantly improve the efficiency of competition. Selecting furazolidone as a model analyte, the immunoassay biosensor showed a limit of detection as low as 0.08 ng/mL, 10-fold decreased than that of the AuNPs-LFIA. Moreover, the Au-SiO2 Janus NP lateral flow immunoassay was well applied in chicken, pork, honey, and beef food samples with visual detection limits of 0.8 ng/g, 0.16 ng/g, 0.4 ng/mL, and 0.16 ng/g, resp. The Au-SiO2 Janus NPs possess the advantages of both materials, which will broaden their applications as a potential alternative in the rapid and sensitive detection of antibiotic residues.

Although many compounds look similar to this compound(16961-25-4)Name: Hydrogen tetrachloroaurate(III) trihydrate, numerous studies have shown that this compound(SMILES:Cl[Au-](Cl)(Cl)Cl.[H]O[H].[H]O[H].[H]O[H].[H+]), has unique advantages. If you want to know more about similar compounds, you can read my other articles.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem