Category: 1384100-95-1

Design, synthesis and binding studies of a novel quadruple ADDA hydrogen-bond array was written by Pellizzaro, Maria L.;Barrett, Simon A.;Fisher, Julie;Wilson, Andrew J.. And the article was included in Organic & Biomolecular Chemistry in 2012.Name: 4-(tert-Butyl)-1H-imidazol-2-amine hydrochloride The following contents are mentioned in the article:

The design and synthesis of a novel ADDA hydrogen-bond array is described. The ureidodiimidazole motif (I UDIM) engages in interactions with complementary diamidonaphthyridine (II DAN) motifs with an association constant K_a = 825 ± 16 M^-1 in chloroform. ¹H NMR and mol. modeling studies were carried out in order to explain the unexpected behavior of this new supramol. motif. These revealed that a combination of effects including; an energetic bias for the folded conformer, subtle differences in shape complementarity between the two components and the potential for self-association of I disfavor higher affinity interactions between the two components. This study involved multiple reactions and reactants, such as 4-(tert-Butyl)-1H-imidazol-2-amine hydrochloride (cas: 1384100-95-1Name: 4-(tert-Butyl)-1H-imidazol-2-amine hydrochloride).

4-(tert-Butyl)-1H-imidazol-2-amine hydrochloride (cas: 1384100-95-1) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Name: 4-(tert-Butyl)-1H-imidazol-2-amine hydrochloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Supramolecular Self-Sorting Networks using Hydrogen-Bonding Motifs was written by Coubrough, Heather M.;van der Lubbe, Stephanie C. C.;Hetherington, Kristina;Minard, Aisling;Pask, Christopher;Howard, Mark J.;Fonseca Guerra, Celia;Wilson, Andrew J.. And the article was included in Chemistry – A European Journal in 2019.Product Details of 1384100-95-1 The following contents are mentioned in the article:

A current objective in supramol. chem. is to mimic the transitions between complex self-sorted systems that represent a hallmark of regulatory function in nature. In this work, a self-sorting network, comprising linear hydrogen motifs, was created. Selecting six hydrogen-bonding motifs capable of both high-fidelity and promiscuous mol. recognition gave rise to a complex self-sorting system, which included motifs capable of both narcissistic and social self-sorting. Examination of the interactions between individual components, exptl. and computationally, provided a rationale for the product distribution during each phase of a cascade. This reasoning holds through up to five sequential additions of six building blocks, resulting in the construction of a biomimetic network in which the presence or absence of different components provides multiple unique pathways to distinct self-sorted configurations. This study involved multiple reactions and reactants, such as 4-(tert-Butyl)-1H-imidazol-2-amine hydrochloride (cas: 1384100-95-1Product Details of 1384100-95-1).

4-(tert-Butyl)-1H-imidazol-2-amine hydrochloride (cas: 1384100-95-1) belongs to imidazole derivatives. Many natural products, especially alkaloids, contain the imidazole ring. These imidazoles share the 1,3-C3N2 ring but feature varied substituents. Imidazole also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes.Product Details of 1384100-95-1

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem