Category: 1116-98-9

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Pentanidium-catalyzed direct assembly of vicinal all-carbon quaternary stereocenters through C(sp3)-C(sp3) bond formation, published in 2021, which mentions a compound: 1116-98-9, mainly applied to vicinal all carbon quaternary stereocenter compound preparation enantioselective diastereoselective; racemic tertiary bromide secondary carbanion substitution reaction pentanidium catalyst, SDS of cas: 1116-98-9.

The stereoselective construction of vicinal all-carbon quaternary stereocenters has long been a formidable synthetic challenge. Direct asym. coupling of a tertiary carbon nucleophile with a tertiary carbon electrophile is the most straightforward approach, but it is sterically and energetically disfavored. Herein, a catalytic asym. substitution, where racemic tertiary bromides coupled directly with racemic secondary or tertiary carbanion, creating a series of congested C(sp3)-C(sp3) bonds, including isolated all-carbon quaternary stereocenters, vicinal tertiary/all-carbon quaternary stereocenters and vicinal all-carbon quaternary stereocenters was described. Using pentanidium as a catalyst, this double stereoconvergent process afforded substituted products in good enantioselectivities and diastereoselectivities.

This literature about this compound(1116-98-9)SDS of cas: 1116-98-9has given us a lot of inspiration, and I hope that the research on this compound(tert-Butyl 2-cyanoacetate) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: tert-Butyl 2-cyanoacetate, is researched, Molecular C7H11NO2, CAS is 1116-98-9, about Synthesis and structure of dialkyl (Z)-3-amino-2-cyano-4-diazopent-2-enedioates, the main research direction is dialkyl aminocyanodiazopentenedioate preparation diastereoselective DFT study; tosyl azide alkyl cyanoacetate diazo transfer reaction pyridine.Formula: C7H11NO2.

Diazo-transfer reaction of tosyl azide and alkyl 2-cyanoacetates in the presence of pyridine at 0° gives the corresponding alkyl 2-cyano-2-diazoacetates. This material readily underwent nucleophilic attack by pyridinium 1-cyano-2-alkoxy-2-oxoethan-1-ide to form dialkyl (Z)-3-amino-2-cyano-4-diazopent-2-enedioates. The X-ray structure of a typical product is reported, as well as DFT computational studies that illuminate the structural features of these stable diazo compounds

This literature about this compound(1116-98-9)Formula: C7H11NO2has given us a lot of inspiration, and I hope that the research on this compound(tert-Butyl 2-cyanoacetate) can be further advanced. Maybe we can get more compounds in a similar way.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Related Products of 1116-98-9. Aromatic compounds can be divided into two categories: single heterocycles and fused heterocycles. Compound: tert-Butyl 2-cyanoacetate, is researched, Molecular C7H11NO2, CAS is 1116-98-9, about Activated 2-methylidene-1,3-thiazolidin-4-ones in a promising approach to the synthesis of polyfunctional thiazolo[3,2-c]pyrimidines. Author is Litvinchuk, Mariia B.; Bentya, Anton V.; Rusanov, Eduard B.; Vovk, Mykhailo V..

A preparatively convenient and efficient synthetic route to new 5H-[1,3]thiazolo[3,2-c]pyrimidine derivatives I (R = cyclopropyl, tert-Bu, methoxy, benzyloxy, tert-butyloxy, Ar = Ph, 3-bromophenyl, 4-chlorophenyl, 4-fluorophenyl) is described that involves the cyclocondensation of acyl or alkoxycarbonyl α-functionalized 2-methylidene-1,3-thiazolidin-4-ones II with 1-chlorobenzyl isocyanates ArCH(Cl)NCO. The optimal reaction conditions, viz., heating reagents in toluene in the absence of an organic base, afford the target products in 48-74% yields. Some tert-Bu 2-(4-oxo-1,3-thiazolidin-2-ylidene)ethanoates produce, along with the desired tert-Bu [1,3]thiazolo[3,2-c]pyrimidine-8-carboxylates I (R = tert-BuO, Ar = Ph, 3-bromophenyl, 4-chlorophenyl), the corresponding 8-carboxylic acids III in 18-21% yields. A reliable structural determination of all the synthesized compounds has been performed by elemental anal. and a number of spectroscopic methods (1H and 13C NMR, HPLC/MS, and FT-IR) as well as by X-ray diffraction anal.

As far as I know, this compound(1116-98-9)Related Products of 1116-98-9 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Synthesis and Catalytic Activities of 3-Decyl-β-proline for Michael Reactions in Water without an Organic Solvent, published in 2021-08-03, which mentions a compound: 1116-98-9, Name is tert-Butyl 2-cyanoacetate, Molecular C7H11NO2, HPLC of Formula: 1116-98-9.

The compound 3-Decyl-β-proline, which has a highly lipophilic substituent, was synthesized, and its catalytic activities in Michael addition using water as the solvent were investigated. The decyl substituent promoted the reaction by hydrophobic interactions to afford the Michael adduct in a high yield and with high diastereoselectivity under low catalyst loading.

As far as I know, this compound(1116-98-9)HPLC of Formula: 1116-98-9 can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 1116-98-9, is researched, Molecular C7H11NO2, about Phenothiazine (or phenoxazine) based (D-π-A)-L2-(A-π-D-π-A)2-type organic dyes with five anchors for efficient dye-sensitized solar cells, the main research direction is phenothiazine organic dye sensitized solar cell.COA of Formula: C7H11NO2.

Developing organic dyes with di-/multi-anchors has aroused increasing attention in recent years due to these dyes had many advantages in comparison with the analogs of single acceptor. Herein, four (D-π-A)-L2-(A-π-D-π-A)2 dyes (TQ1-2, OQ1-2) along with a reference D-(π-A)2 dye (TD), comprising phenothiazine/phenoxazine as a donor, thiophene as a π space, cyanoacetic acid as an acceptor and saturated n-hexyl/n-dodecyl as a flexible linker have been prepared and characterized. The correlative between the variation of structure and the optical, electrochem. properties in addition to photovoltaic performances of the dyes have been explored. Besides, the UV-visible spectra in solution and on the TiO2 film, cyclic voltammetry, photocurrent-voltage scan, incident photon-to-current conversion efficiency and electrochem. impedance spectroscopic of the presented dyes have been investigated. Compared with the reference dye TD, TQ1-2 and OQ1-2 exhibit higher molar extinction coefficient, broader and stronger incident photon-to-current conversion efficiency response spectrum, and higher d. of light-absorbing units adsorbed on the TiO2 surface. Among the cells based on the pristine dyes, the relatively high photocurrent of OQ1-2 by comparison with the counterparts of TQ1-2 is attributed to the incorporation of phenoxazine donor into the (A-π-D-π-A)2 units. An increase open-circuit voltage of TQ2 and OQ2 compared to TQ1 and OQ1 is ascribed to the higher charge recombination resistance and the longer electron lifetime in their cells. Consequently, a maximum power conversion efficiency of 6.77% is attained by the TQ2-based cells with iodide/triiodide electrolyte under the illumination of 100 mW cm-2.

From this literature《Phenothiazine (or phenoxazine) based (D-π-A)-L2-(A-π-D-π-A)2-type organic dyes with five anchors for efficient dye-sensitized solar cells》,we know some information about this compound(1116-98-9)COA of Formula: C7H11NO2, but this is not all information, there are many literatures related to this compound(1116-98-9).

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Asian Journal of Organic Chemistry called Visible Light Photocatalytic Trifluoromethylation/SET Oxidation/Cycloaddition Sequences of 2-Vinyl Phenols: Multicomponent Synthesis of 4H-Chromenes, Author is Jang, Jihoon; Kim, Dae Young, which mentions a compound: 1116-98-9, SMILESS is O=C(OC(C)(C)C)CC#N, Molecular C7H11NO2, Computed Properties of C7H11NO2.

Visible light-mediated photocatalytic trifluoromethylation, single electron transfer (SET) oxidation, and cycloaddition cascades of 2-vinyl phenols with Umemoto’s reagent and malononitrile were developed. This approach provided the multicomponent synthesis of trifluoromethylated 4H-chromenes I [R = H, 6-Me, 6,8-di-Br, etc.; R1 = CN, CO2Me, CO2t-Bu] via the in situ generation of o-quinone methides, followed by sequential cyclization.

From this literature《Visible Light Photocatalytic Trifluoromethylation/SET Oxidation/Cycloaddition Sequences of 2-Vinyl Phenols: Multicomponent Synthesis of 4H-Chromenes》,we know some information about this compound(1116-98-9)Computed Properties of C7H11NO2, but this is not all information, there are many literatures related to this compound(1116-98-9).

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Application of 1116-98-9. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: tert-Butyl 2-cyanoacetate, is researched, Molecular C7H11NO2, CAS is 1116-98-9, about CuI/I2-Catalyzed Concise Synthesis of Substituted 6-Aminoisoquinolinoquinazoline Carboxylates from Anthranilamide. Author is Gal Reddy, Potuganti; Reddy Indukuri, Divakar; Alla, Manjula.

A one pot sequential addition protocol for synthesis of polycyclic quinazolines with β-amino acid motifs has been achieved starting from anthranilamide. Initial in situ formation of 2-(2-bromophenyl)quinazolin-4(3H)-one followed by addition of alkyl cyanoacetates catalyzed by copper (I) salts gives the target compound in good to excellent yields. The expedient and facile cascade protocol involves nucleophilic α-arylation, intramol. cycloamidation of nitriles followed by 1,3-hydrogen shift allowing direct access to 6-amino-8-oxo-8H-isoquinolino[1,2-b]quinazoline-5-carboxylates I (R = CN, COOMe, COOt-Bu, COOBn, etc.; R1 = H, 10-Cl, 10-F; R2 = H, 2-F, 3-Me, etc.).

If you want to learn more about this compound(tert-Butyl 2-cyanoacetate)Application of 1116-98-9, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1116-98-9).

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: tert-Butyl 2-cyanoacetate, is researched, Molecular C7H11NO2, CAS is 1116-98-9, about Quaternary stereocentres via catalytic enantioconvergent nucleophilic substitution reactions of tertiary alkyl halides.SDS of cas: 1116-98-9.

The development of efficient methods, particularly catalytic and enantioselective processes, for the construction of all-carbon quaternary stereocentres is an important (and difficult) challenge in organic synthesis due to the occurrence of this motif in a range of bioactive mols. One conceptually straightforward and potentially versatile approach is the catalytic enantioconvergent substitution reaction of a readily available racemic tertiary alkyl electrophile by an organometallic nucleophile; however, examples of such processes are rare. Here we demonstrate that a nickel-based chiral catalyst achieves enantioconvergent couplings of a variety of tertiary electrophiles (cyclic and acyclic α-halocarbonyl compounds) with alkenylmetal nucleophiles to form quaternary stereocentres with good yield and enantioselectivity under mild conditions in the presence of a range of functional groups. These couplings, which probably proceed via a radical pathway, provide access to an array of useful families of organic compounds, including intermediates in the total synthesis of two natural products, (-)-eburnamonine and madindoline A.

If you want to learn more about this compound(tert-Butyl 2-cyanoacetate)SDS of cas: 1116-98-9, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1116-98-9).

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Design and Synthesis of 56 Shape-Diverse 3D Fragments, published in 2020-07-25, which mentions a compound: 1116-98-9, mainly applied to alkyl piperidine pyrrolidine fragment diastereoselective preparation; 3D fragments; conformational diversity; fragment-based drug discovery; medicinal chemistry; synthesis design, Electric Literature of C7H11NO2.

Fragment screening collections were often predominantly populated with flat, 2D mols. A workflow for the design and synthesis of 56 3D disubstituted pyrrolidine and piperidine fragments that occupy under-represented areas of fragment space (as demonstrated by a principal moments of inertia (PMI) anal.) was described. A key, and unique, underpinning design feature of this fragment collection was that assessment of fragment shape and conformational diversity (by considering conformations up to 1.5 kcal mol-1 above the energy of the global min. energy conformer) was carried out prior to synthesis and was also used to select targets for synthesis. The 3D fragments were designed to contain suitable synthetic handles for future fragment elaboration. Finally, by comparing our 3D fragments with six com. libraries, it was clear that our collection was high three-dimensionality and shape diversity.

If you want to learn more about this compound(tert-Butyl 2-cyanoacetate)Electric Literature of C7H11NO2, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1116-98-9).

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Recommanded Product: 1116-98-9. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: tert-Butyl 2-cyanoacetate, is researched, Molecular C7H11NO2, CAS is 1116-98-9, about Selective Anchoring Groups for Molecular Electronic Junctions with ITO Electrodes. Author is Planje, Inco J.; Davidson, Ross J.; Vezzoli, Andrea; Daaoub, Abdalghani; Sangtarash, Sara; Sadeghi, Hatef; Martin, Santiago; Cea, Pilar; Lambert, Colin J.; Beeby, Andrew; Higgins, Simon J.; Nichols, Richard J..

Indium tin oxide (ITO) is an attractive substrate for single-mol. electronics since it is transparent while maintaining elec. conductivity Although it has been used before as a contacting electrode in single-mol. elec. studies, these studies have been limited to the use of carboxylic acid terminal groups for binding mol. wires to the ITO substrates. There is thus the need to investigate other anchoring groups with potential for binding effectively to ITO. With this aim, we have investigated the single-mol. conductance of a series of eight tolane or “”tolane-like”” mol. wires with a variety of surface binding groups. We first used gold-mol.-gold junctions to identify promising targets for ITO selectivity. We then assessed the propensity and selectivity of carboxylic acid, cyanoacrylic acid, and pyridinium-squarate to bind to ITO and promote the formation of mol. heterojunctions. We found that pyridinium squarate zwitterions display excellent selectivity for binding to ITO over gold surfaces, with contact resistivity comparable to that of carboxylic acids. These single-mol. experiments are complemented by surface chem. characterization with XPS, quartz crystal microbalance, contact angle determination, and nanolithog. using an at. force miscroscope. Finally, we report the first d.-functional theory calculations involving ITO electrodes to model charge transport through ITO-mol.-gold heterojunctions.

If you want to learn more about this compound(tert-Butyl 2-cyanoacetate)Recommanded Product: 1116-98-9, you may wish to communicate with the author of the article,or consult the relevant literature related to this compound(1116-98-9).

Reference:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem