Category: 1072-63-5

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1072-63-5, name is 1-Vinyl-1H-imidazole, A new synthetic method of this compound is introduced below., name: 1-Vinyl-1H-imidazole

(1) Add an appropriate amount of acetonitrile as a solvent to dissolve N-vinylimidazole in a three-necked flask for later use, weigh and configure it as Br (CH2) 6Br:N-vinylimidazole = 1: 2 (molar ratio) mixed product is ready for use; N-vinylimidazole acetonitrile solution is circulated at 82 C under reflux conditions.The above mixture was added dropwise to a three-necked flask and continuously stirred for 24 h.After the reaction, a pale yellow liquid was obtained, and the residual solvent was evaporated under reduced pressure.It was washed several times with ethyl acetate and acetone successively; the product was dried under vacuum to obtain (ViIm) 2C6 (Br) 2.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; Chengdu Mingdian Shijia Biological Technology Co., Ltd.; Song Hang; (15 pag.)CN110590675; (2019); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 1072-63-5, name is 1-Vinyl-1H-imidazole, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C5H6N2

General procedure: 5 mmol of 1-vinylimidazole, 5 mmol of ethyl bromide were added to 30 mL of methanol in a 100 mL roundbottom flask at 0C. The mixture was stirred at room temperature overnight, followed by 60C for 15 h. After cooling down, the reaction mixture was added dropwise into 250 mL of diethyl ether and a white precipitate was formed. The precipitate was filtered off and washed with diethyl ether again and dried at room temperature until constant weight. (1H NMR, CDCl3, d ppm): 1.66 (t, 3H), 4.53(q, 2H), 5.42 (d, 1H), 6.00 (d, 1H), 7.48 (dd, 1H), 7.70 (s, 1H),7.87 (s, 1H), 10.97 (s, 1H).

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 1072-63-5.

Reference:
Article; Pourjavadi, Ali; Hosseini, Seyed Hassan; AghayeeMeibody, Seyyed Alireza; Hosseini, Seyedeh Talieh; Comptes Rendus Chimie; vol. 16; 10; (2013); p. 906 – 911;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Reference of 1072-63-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1072-63-5, name is 1-Vinyl-1H-imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.

Comprising the steps of: 0.840 g of alpha-mercaptomethyltrimethoxysilane prepared in Example 6 and 1.176 g of 1-Vinylimidazole were placed in a round bottom flask wrapped in aluminum box paper. Then, 8 mL of tetrahydrofuran was added, and after mixing uniformly, 0.076 g of benzoin dimethyl ether was added, the mixture was uniformly stirred, the aluminum box paper was removed, and irradiated at room temperature for 30 minutes under a UV lamp having a power of 20 W and a wavelength of 365 nm. After the completion of the reaction, the solvent was distilled off under reduced pressure, and the degree of vacuum was 5 to 6 mmHg, which was precipitated three times in n-hexane, and dried under vacuum at 40 C to a constant weight to obtain alpha-(1-ethylimidazolyl)mercaptomethyltrimethoxysilane, purity 96%, yield 96%. The infrared spectrum of the product alpha-(1-ethylimidazolyl)mercaptomethyltrimethoxysilane obtained in this example is shown in Fig. 19, and the nuclear magnetic resonance spectrum is shown in Fig. 20. 19 and 20, the product obtained in this example was alpha-(1-ethylimidazolyl)mercaptomethyltrimethoxysilane

The synthetic route of 1-Vinyl-1H-imidazole has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Shandong University; Bei Yiling; Gao Yanhong; Zhu Qingzeng; Feng Shengyu; (24 pag.)CN109053794; (2018); A;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem