Category: 1072-63-5

Electric Literature of 1072-63-5, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1072-63-5, name is 1-Vinyl-1H-imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below.

General procedure: Bis-vinylimidazolium bromoethane ([CnDVIM]Br) were synthesized by the reaction between 1-vinylimidazole and (CH2)2Br2, (CH2)4Br2, or (CH2)8Br2 [20]. Typically, 1-vinylimidazole (4.20g, 44.6mmol) and (CH2)nBr2 (21.7mmol) were dissolved in 5.0mL methanol. Then, the mixture was continuously magnetic stirred for 5min to get a homogenous solution and poured into a 50mL single-necked flask. After aerated nitrogen for about 3min, the flask was sealed and placed into 65C oil bath with a continuously magnetic stirring for 24h. After cooling to room temperature, excess diethyl ether (200mL) was poured into the solution and the crude salt was obtained. The obtained salt was washed with diethyl ether three times and dried under vacuum to get the yellow [CnDVIM]Br.

The synthetic route of 1-Vinyl-1H-imidazole has been constantly updated, and we look forward to future research findings.

Reference:
Article; Liu, Yang; Zhao, Jia; He, Fang; Zheng, Chen; Zhao, Xiaopeng; Yin, Jianbo; Polymer; vol. 171; (2019); p. 161 – 172;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Application of 1072-63-5, These common heterocyclic compound, 1072-63-5, name is 1-Vinyl-1H-imidazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Typically, 1,4-butanediyl-3,3?-bis-L-vinylimidazolium dibromide(BVD) was synthesized based on a reported method[94]. 1-Vinylimidazole (2.82 g, 30 mmol) was dissolved in15 mL ethanol, and 1,4-dibromobutane (3.24 g, 15 mmol) in15 mL ethanol was added dropwise to the 1-vinylimidazolesolution. The mixture was stirred at 60 C for 10 h. After cooling of the reaction flask to ambient temperature, the reaction mixture was added dropwise into 500 mL of drydiethyl ether. The white powder was separated and dried at room temperature.1,4-Butanediyl-3,3?-bis-L-vinylimidazolium dibromide(Mp = 148 C). 1H NMR (DMSO-d6, delta, ppm): 9.55 (2H),8.28 (2H), 7.93 (2H), 7.47 (2H), 5.92 (2H), 5.42 (2H), 4.30(4H), 1.82 (4H). 13C NMR (DMSO-d6, delta, ppm): 134.9,129.4, 123.8, 120.1, 109.2, 49.3, 26.4.

Statistics shows that 1-Vinyl-1H-imidazole is playing an increasingly important role. we look forward to future research findings about 1072-63-5.

Reference:
Article; Maleki, Maryam; Baghbanian, Seyed Meysam; Tajbakhsh, Mahmood; Journal of the Iranian Chemical Society; vol. 15; 2; (2018); p. 359 – 368;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1072-63-5, name is 1-Vinyl-1H-imidazole, A new synthetic method of this compound is introduced below., Recommanded Product: 1072-63-5

[1,1?-(Butane-1,4-diyl)-bis(3-vinylimidazolium)]Br2 ([BVIM]Br2): [BVIM]Br2 was prepared according to the previous report [26]. N-vinylimidazole (18.84 g, 0.20 mol) and 1,4 dibromobutane (0.10 mol) were dissolved in isopropanol (50 mL) at 80 C for 24 h under nitrogen atmosphere. On completion, the white solid of [BVIM]Br2 was obtained after the removing of solvent and washing with THF (yield: 90%). 1H NMR (300 MHz, D2O, TMS) delta (ppm) = 2.00 (s, 2H, -CH2), 4.34 (s, 2H, -CH2), 5.44 (d, 1H, -CH), 5.86 (d, 1H, -CH), 7.18 (m, 1H, -CH), 7.63 (s, 1H, -CH), 7.81 (s, 1H, -CH), 9.11 (s, 1H, -CH).

The synthetic route of 1072-63-5 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Leng, Yan; Zhang, Weijie; Wang, Jun; Jiang, Pingping; Applied Catalysis A: General; vol. 445-446; (2012); p. 306 – 311;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Related Products of 1072-63-5, These common heterocyclic compound, 1072-63-5, name is 1-Vinyl-1H-imidazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

1-Vinylimidazole (5 g, 53.1 mmol) was taken in a 100-mL round-bottomedflask. To this, n-bromoethane (6.947 g, 63.7 mmol) was added andheated at 60 C for 3 h to produce 1-vinyl 3-ethylimidazolium bromide[ViEIm]Br in quantitative yields.

Statistics shows that 1-Vinyl-1H-imidazole is playing an increasingly important role. we look forward to future research findings about 1072-63-5.

Reference:
Article; Pothanagandhi, Nellepalli; Sivaramakrishna, Akella; Vijayakrishna, Kari; Reactive and functional polymers; vol. 106; (2016); p. 132 – 136;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Electric Literature of 1072-63-5, These common heterocyclic compound, 1072-63-5, name is 1-Vinyl-1H-imidazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Typically, 1-vinylimidazole (5 g, 15 mmol) and an excess molar amount of 1-bromododecane (7 g, 7 mmol) were loaded into a 100 mL reactor. The mixture was stirred at room temperature overnight, followed at 60 C for 24 h. After cooling down, the reaction mixture was added dropwise into 250 mL of diethyl ether and white precipitate was formed. The precipitate was filtered off and washed with diethyl ether again and dried at room temperature until constant weight (95% yields). The formed solid was dissolved in 20 mL CH2Cl2 in a 50 mL round bottom flask, and aqueous HBF4 (50%) at a 1.1 + 1 M ratio was slowly dropped into the flask. After one week, [C12vim][BF4] was separated by extraction with distilled water. The organic layer was collected, dried over Na2SO4, filtered and the solvent removed in vacuum to give the product. (0007) [C12vim][Br]: 1H NMR (DMSO-d6, delta ppm): 9.53 (1H), 8.20 (1H), 7.93 (1H), 7.28 (1H), 5.95 (1H), 5.41 (1H), 4.18 (2H), 1.81 (2H), 1.23 (18H), 0.85 (3H). Anal. calculated for C17H31N2Br: C, 50.88; H, 10.95; N, 9.89. Found: C, 57.99; H, 9.35; N, 8.00. (0008) [C12vim][BF4]: 1H NMR (DMSO-d6, delta ppm): 9.45 (1H), 8.18 (1H), 7.91 (1H), 7.27 (1H), 5.93 (1H), 5.41 (1H), 4.17 (2H), 1.81 (2H), 1.25 (18H), 0.85 (3H). 19F NMR (DMSO-d6, delta ppm): -148.73. Anal. calculated for C17H31N2BF4: C, 49.69; H, 10.70; N, 9.66. Found: C, 59.15; H, 9.41; N, 7.85; Br, 0.

Statistics shows that 1-Vinyl-1H-imidazole is playing an increasingly important role. we look forward to future research findings about 1072-63-5.

Reference:
Article; Pourjavadi, Ali; Doulabi, Malihe; Hosseini, Seyed Hassan; Polymer; vol. 53; 25; (2012); p. 5737 – 5742;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1072-63-5, name is 1-Vinyl-1H-imidazole belongs to imidazoles-derivatives compound, it is a common compound, a new synthetic route is introduced below. COA of Formula: C5H6N2

1-vinyl imidazole (5.18 g, 55 mmol) and 1,6-dibromohexane (2.79 g, 22 mmol) were dissolved in methanol (50 mL) in a round-bottom flask fitted with a condenser and N2 bubbler. Subsequently, the mixture was stirred at 80 C for 48 h under a nitrogen atmosphere. After then, the reaction mixture was precipitated from diethyl ether (150 mL), and recrystallized twice from diethyl ether. The products were dried under vacuum for 24 h at R.T. [C6VIm]Br was obtained as white solid. Yield: 71%. [C6VIm]Br: 1H-NMR (D2O, 400 MHz, ppm):7.57 (1H, s); 7.37 (1H, s); 6.93 (1H, m); 5.60 (1H, d); 5.22 (1H, d); 4.04 (2H, t); 1.70 (2H, s); 1.17 (2H, s).1H-NMR (DMSO, 400 MHz, ppm): 9.66 (1H, s); 8.24 (1H, t); 7.99 (1H, t); 7.33 (1H, m); 5.99 (1H, m);5.43 (1H, m); 4.22 (2H, t); 1.83 (2H, d); 1.31 (2H, s). 13C-NMR (DMSO, 100 MHz, ppm): 135.36,128.88, 123.31, 119.23, 109.04, 49.02, 28.80, 24.77. ESI-MS (m/z): calcd. for C16H24N4Br2: 432.2,found: 432.2. Elemental analysis (%): Calculated: C, 44.46; H, 5.60; N, 12.96; Br, 36.98. Found: C,42.94; H, 5.36; N, 12.50; Br, 39.20. M.P.: 219 C.

The synthetic route of 1072-63-5 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Zhang, Jing; Liu, Jingjiang; Zuo, Yong; Wang, Rongmin; Xiong, Yubing; Molecules; vol. 20; 9; (2015); p. 17378 – 17392;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1072-63-5, name is 1-Vinyl-1H-imidazole, A new synthetic method of this compound is introduced below., HPLC of Formula: C5H6N2

With reference to FIG. 4, 0.14 mmloe of 1-vinylimidazole, being the imidazolium liquid monomer, and 50 ml of toluene are mixed to obtain a mixture, followed by sequentially dropping 0.16 mmole of 2-bromoethanol into the mixture to trigger off an alkylation of the 1-vinylimidazole and the 2-bromoethanol. Then, a solution with two phase of layering is obtained after three days of reaction, wherein the lower layer of the solution is further isolated and repeatedly washed by toluene and ether, followed by being condensed and dried in vacuo for 1 hour, to obtain 1-(2-hydroxyl-ethyl)-3-vinylimidazolium bromide (also known as HEVIMB).

The synthetic route of 1072-63-5 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; HORNG, Shiey-Shiun; US2013/274485; (2013); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

Electric Literature of 1072-63-5, Children learn through play, and they learn more than adults might expect. Science experiments are a great way to spark their curiosity, 1072-63-5, Name is 1-Vinyl-1H-imidazole, SMILES is C=CN1C=CN=C1, belongs to imidazoles-derivatives compound. In a article, author is Xu, Kun, introduce new discover of the category.

Atom-Economic, Regiodivergent, and Stereoselective Coupling of Imidazole Derivatives with Terminal Allenes

New Rh- and Pd-catalyzed regiodivergent and stereoselective intermolecular coupling reactions of imidazole derivatives with mono-substituted allenes are herein reported. Using a Rh-I/Josiphos system, perfect regioselectivities and high enantiomeric excess were obtained, while a Pd-II/dppf system gave linear products with high regioselectivities and high E/Z selectivities. This method permits the atom economic synthesis of valuable branched and linear allylic imidazole derivatives.

Electric Literature of 1072-63-5, Because enzymes can increase reaction rates by enormous factors and tend to be very specific, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 1072-63-5.

In an article, author is Macchiarulo, A, once mentioned the application of 1072-63-5, Recommanded Product: 1-Vinyl-1H-imidazole, Name is 1-Vinyl-1H-imidazole, molecular formula is C5H6N2, molecular weight is 94.1145, MDL number is MFCD00005297, category is imidazoles-derivatives. Now introduce a scientific discovery about this category.

1,4-benzothiazine and 1,4-benzoxazine imidazole derivatives with antifungal activity: A docking study

We have recently described the synthesis and antifungal activity of a series of 1,4-benzothiazine and 1,4-benzoxazine imidazole derivatives that mainly showed in vivo activity against a murine experimental model of candidiasis but that very often lacked in vitro activity. Here, we report a docking study of a representative set of our molecules in a 3D model of CYP51 of Candida albicans (CA-CYP51). The model was constructed on the basis of the sequence homology relationship with the recently reported crystal structure of the CYP51 of Mycobacterium tuberculosis (MT-CYP51). (C) 2002 Elsevier Science Ltd. All rights reserved.

If you are interested in 1072-63-5, you can contact me at any time and look forward to more communication. Recommanded Product: 1-Vinyl-1H-imidazole.

Electric Literature of 1072-63-5, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 1072-63-5, Name is 1-Vinyl-1H-imidazole, SMILES is C=CN1C=CN=C1, belongs to imidazoles-derivatives compound. In a article, author is Xu, ZX, introduce new discover of the category.

Design, synthesis and properties of imidazole derivatives for second-order nonlinear optics

Two conjugated donor-acceptor imidazole derivatives for second-order nonlinear optics were designed and synthesized. The thermal properties, the transparency and second-order nonlinear optical properties of these chromophores were investigated. Experimental results indicate that a good nonlinearity-transparency-thermal stability trade-off was achieved for them.

Electric Literature of 1072-63-5, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 1072-63-5 is helpful to your research.