Category: 10057-46-2

Synthetic Route of 10057-46-2, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 10057-46-2, name is 2-Amino-5-(trifluoromethyl)benzoimidazole, This compound has unique chemical properties. The synthetic route is as follows.

2-(2,3-Dih drobenzofuran-5-yl)-N-(5-(trifluoromethyl)-lH-bcnzo[Patent; 4SC DISCOVERY GMBH; LEBAN, Johann; ZAJA, Mirko; WO2014/202638; (2014); A1;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem

These common heterocyclic compound, 10057-46-2, name is 2-Amino-5-(trifluoromethyl)benzoimidazole, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. HPLC of Formula: C8H6F3N3

48.8 mg (0.179 MMOL) 4,32. 8 mg (0.163 mmol) 5,68 mg (0.212 mmol) TBTU and 7.5 mg (0.049 MMOL) HOBT are dissolved in 1.8 ml DMF and treated with 0. 11 ML (0. 652 MMOL) DIPEA. After three hours of stirring at room temperature, approx. 2 ML water are added to the reaction mixture, whereby a precipitate is obtained. The precipitate is filtered by suction, washed with water and digested with little methanol. Yield : 27.5 mg (37%) 6, colourless solid

The synthetic route of 2-Amino-5-(trifluoromethyl)benzoimidazole has been constantly updated, and we look forward to future research findings.