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NOVEL IMIDAZOLE DERIVATIVES AS POTENTIAL AGROCHEMICALS – SYNTHETIC AND MECHANISTIC STUDIES

The importance of the imidazole nucleus is briefly outlined and some naturally occurring derivatives listed. The problem associated with direct alkylation on the imino nitrogen is discussed and synthesis of 1-alkyl derivatives by the thermal decarboxylation of 1-alkoxycarbonylimidazoles examined as a possible alternative. Spectroscopic investigation of this mechanism is reported. The fungal threat to plantains in the tropics by black sigatoka and the option of chemical control are discussed. Synthesis of potential fungicides are reported.

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Synthesis of highly functional imidazole derivatives via assembly of 2-unsubstituted imidazole N-oxides with CH-acids and arylglyoxals

A novel and convenient method for the synthesis of a wide range of polyfunctional imidazole derivatives based on the three-component condensation of imidazole N-oxides with CH-acids and arylglyoxals has been developed. This reaction proceeds smoothly in moderate-to-good yields with a wide range of starting materials. (C) 2020 Elsevier Ltd. All rights reserved.

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Computational study of imidazole derivative as high energetic materials

Density functional theory (DFT) calculations were performed for a series of imidazole derivatives. B3LYP and B3P86 functionals with 6-31G** basis set were used. Heats of formation (HOFs) were predicted through designed isodesmic reactions. Calculated results show that the HOFs relate to the number and the position of nitro groups. The HOFs increase with the augment of the number of the NO2 group for the direct imidazole derivatives and decrease with the augment of the number of the NO2 group for 1-picrylimidazole derivatives. Thermal stabilities were evaluated via bond dissociation energies (BDEs). The result shows that the increase of nitro group number on imidazole ring reduces the stability of the molecule. Further, the correlation was developed between impact sensitivity h(50) and the ratio (BDE/E) of the weakest bond BDE to the total energy E. The detonation performance data were also calculated. (c) 2010 Elsevier B.V. All rights reserved.

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SYNTHESES AND ANTIFUNGAL ACTIVITIES OF 1-[4-PHENYL-2-(PHENYLTHIO OR ACYLOXY)-NORMAL-BUTYL]-1H-IMIDAZOLE DERIVATIVES

The title compounds (4b, d-f, h-j) were prepared from 1-[4-(p-substituted phenyl)-2-chloro-n-butyl]-1H-imidazoles and the corresponding thiophenols or mercaptopyridines. Acyloxy compounds (5a-e) were prepared from alcohol (2b) and the corresponding acyl chlorides. In the antifungal activity test, p-tolyl compounds (4e, f) showed as good activity as butoconazole (4c).

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Synthesis and pharmacological evaluation of imidazole derivatives of some non-steroidal anti-inflammatory drugs

A series of Imidazole derivatives of NSAIDs (4a-1) have been prepared by condensation of NSAIDs hydrazides (1,2) with substituted oxazolones and evaluated for anti-inflammatory and gastrointestinal toxicity, which showed good anti-inflammatory activity and reduced gastrointestinal toxicity as compared to parent drug.

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Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 10045-45-1, Name is 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one, molecular formula is C9H10N2O, belongs to imidazoles-derivatives compound, is a common compound. In a patnet, author is Sharma, AK, once mentioned the new application about 10045-45-1, Formula: C9H10N2O.

Synthesis of functionalised cyclic nitrones via regioselective and unusual [3+2] cycloadditions of alpha-nitrosostyrenes with 1,3-diazabuta-1,3-dienes and imines

The alpha-nitrosostyrenes 2, generated in situ from a-halogeno oximes, undergo regioselective [3 + 2] cycloaddition with 1,3-diazabuta-1,3-dienes 1 and 5 leading to the cyclic nitrones 3 and 6, respectively, Similarly, the cyclic nitrones 12 are also formed in reactions of 2 with the trisubstituted amidines 11, Thermolysis of the nitrones 3 and 12d-f gives imidazole derivatives 13, The nitrones 6, on the other hand, on thermolysis under similar conditions, give the amidine derivatives 17, Interestingly, the treatment of both 3 and 6 with NaBH4 in methanol and the reactions of 2 with N-arylbenzamidines also yield the imidazole derivatives 13.

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Reference of 10045-45-1, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 10045-45-1, Name is 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one, SMILES is O=C1N(CC)C2=CC=CC=C2N1, belongs to imidazoles-derivatives compound. In a article, author is Chen, Ximing, introduce new discover of the category.

Organic dyes with imidazole derivatives as auxiliary donors for dye-sensitized solar cells: Experimental and theoretical investigation

In order to study the influence of different imidazole derivatives in triphenylamine-based organic dyes, two different imidazole derivatives are introduced into the phenyl ring of the triphenylamine core, coded as CD-4 and CD-6, respectively. Their photophysical, electrochemical properties and the performances of the corresponding dye-sensitized solar cells (DSSCs) are further investigated. Due to the better molar extinction coefficient, quantum efficiency (QE) and longer lifetime of excited electron, the DSSC based on CD-4 has the higher overall conversion efficiencies as 4.11% than that of CD-6 as 1.51% under full sunlight (AM 1.5G, 100 mW cm(-2)) irradiation. Density functional theory (DFT) and time dependent density functional theory (TD-DFT) calculations were carried out to study the ground state structures, the electronic structures and the optical properties of the two dyes. The simulated UV-vis absorption spectra for the two dyes are in excellent agreement with the experimental results. (C) 2014 Elsevier Ltd. All rights reserved.

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Related Products of 10045-45-1, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 10045-45-1, Name is 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one, SMILES is O=C1N(CC)C2=CC=CC=C2N1, belongs to imidazoles-derivatives compound. In a article, author is Safa, Kazem D., introduce new discover of the category.

Synthesis of 2-aryl-1,1-bis(silyl)alkenes-containing tetrasubstituted imidazoles catalysed by M-Cu/ZSM-5 (M: Cr, Mn, Co, Ni, V, Zn and Fe) zeolites-supported bimetallic nanostructures

The one-pot synthesis of tetrasubstituted imidazoles by using a series of M-Cu/ZSM-5 (M: Cr, Mn, Co, Ni, V, Zn and Fe) zeolites-supported bimetallic catalysts was studied. Fe-Cu/ZSM-5 bimetallic oxide catalyst had the highest activity in improving the efficiency of the heterogeneous cyclo-condensation reaction. Some imidazole derivatives terminated by vinylbis(silanes) have been synthesised using (Me3Si)(3)CLi through the Peterson olefination reaction.

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Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 10045-45-1, Name is 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one, SMILES is O=C1N(CC)C2=CC=CC=C2N1, belongs to imidazoles-derivatives compound. In a document, author is Jadhav, Ganesh R., introduce the new discover, COA of Formula: C9H10N2O.

Synthesis and characterization of some novel 2-{2-[1-(3-substituted-phenyl)-1H-1,2,3-triazol-4-yl-] ethyl}-1-substituted-1H-benzo [d] imidazole derivatives

Synthesis of some novel 2-{2-[1-(3 -substitutedphenyl)-1H-1,2,3-triazol-4-yl -]ethyl)-1H-benzo [d] imidazole derivatives, by the condensation of o-phenylenediamine with 3-(1-(3-substituted-phenyl)-1H-1,2,3-triazol-4-yl) propanoic acid and then subsequent reactions with different substituted alkyl halides as electrophiles are mentioned. The synthesized compounds were characterized by H-1 NMR, EI-MS and IR spectroscopic techniques.

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Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Name: 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one, 10045-45-1, Name is 1-Ethyl-1H-benzo[d]imidazol-2(3H)-one, SMILES is O=C1N(CC)C2=CC=CC=C2N1, belongs to imidazoles-derivatives compound. In a document, author is Parmar, Tejasvi H., introduce the new discover.

Synthesis and antimicrobial activity of some new of 2-(furan-2-yl)-1-(piperidin-4-yl)-1H-benzo[d]imidazole derivatives

We report a series of new heterocyclic compounds containing the imidazole scaffold were synthesized such as 2-(furan-2-yl)-1-(piperidine-4-yl)-1H-benzo[d]imidazole derivative. Due to the biological activities of imidazole as antimicrobial agents, in the present work, all the synthesized compounds were characterized by H-1 NMR and LC-MS analysis and some of the compounds are characterized by C-13 NMR. All the synthesized compounds were evaluated for their antimicrobial activity against Gram +ve and Gram -ve bacteria and different fungal species which demonstrated good to moderate antimicrobial activity, in which compounds 7b and 7I shows highest antimicrobial activity. [GRAPHICS] .

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