Zhang, Juan published the artcileSynthesis of substituted phenylcarbamates of N-cyclobutylformylated chitosan and their application as chiral selectors in enantioseparation, Application of Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, the publication is Analyst (Cambridge, United Kingdom) (2016), 141(14), 4470-4480, database is CAplus and MEDLINE.
The goal of this study was to develop new chiral stationary phases (CSPs) with high chiral recognition capability and high compatibility with the so-called nonstandard solvents. Seven new chitosan bis(phenylcarbamate)-(N-cyclobutylformamide) derivatives were synthesized from chitosan with high degree of deacetylation as a starting material. The corresponding chiral stationary phases (CSPs 1-7) were prepared with the chitosan derivatives as chiral selectors (CSs). The enantioseparation capability of CSPs 1-7 was evaluated by HPLC with nineteen analytes. In comparison with the CSPs of cellulose tris(3,5-dimethylphenylcarbamate) (CDMPC) and amylose tris(3,5-dimethylphenylcarbamate) (ADMPC), the prepared CSPs generally demonstrated excellent enantioseparation capability, particularly for the CSP derived from chitosan bis(3-chloro-4-methylphenylcarbamate)-(N-cyclobutylformamide). Also, the CSPs in the present study could sep. some analytes better, making them complementary for enantioseparations with the CSPs of CDMPC and ADMPC. The tolerability of the CSP with the best enantioseparation capability to organic solvents was studied. It could work in pure Et acetate, pure chloroform, and a normal phase containing 70% THF, which are prevented from enantioseparation by the coating type CSPs of CDMPC and ADMPC. As these chitosan derivatives were almost insoluble in most organic solvents, the corresponding CSPs can work in a wide range of mobile phases. The influence of the position and electron effects of Me and chloro groups introduced onto the CSs and the composition of mobile phases on enantioseparation is also discussed.
Analyst (Cambridge, United Kingdom) published new progress about 161796-78-7. 161796-78-7 belongs to imidazoles-derivatives, auxiliary class Membrane Transporter/Ion Channel,Proton Pump, name is Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide, and the molecular formula is C17H18N2O6, Application of Sodium (S)-6-methoxy-2-(((4-methoxy-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)benzo[d]imidazol-1-ide.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem