Punna, Sreenivas published the artcile“Clickable” agarose for affinity chromatography, Recommanded Product: N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, the publication is Bioconjugate Chemistry (2005), 16(6), 1536-1541, database is CAplus and MEDLINE.
Successful purification of biol. mols. by affinity chromatog. requires the attachment of desired ligands to biocompatible chromatog. supports. The Cu(I)-catalyzed cycloaddition of azides and alkynes, i.e., the premier example of “click chem.”, is an efficient way to make covalent connections among diverse mols. and materials. Both azide and alkyne units are highly selective in their reactivity, being inert to most chem. functionalities and stable to wide ranges of solvent, temperature, and pH. The authors show that agarose beads bearing alkyne and azide groups can be easily made and are practical precursors to functionalized agarose materials for affinity chromatog.
Bioconjugate Chemistry published new progress about 359860-27-8. 359860-27-8 belongs to imidazoles-derivatives, auxiliary class Other Aliphatic Heterocyclic,Chiral,Amine,Amide,Ether,Inhibitor, name is N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide, and the molecular formula is C18H34N4O5S, Recommanded Product: N-(2-(2-(2-(2-Aminoethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem