Rooney, E. K. published the artcileInteraction of antihistamines with lipid bilayers, Safety of N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, the publication is Biochemical Pharmacology (1979), 28(14), 2199-205, database is CAplus and MEDLINE.
All the 10 H1-antagonists tested reduced the phase transition temperature of a dipalmitoyl phosphatidylcholine lipid bilayer. The binding constants for the drug to the lipid were calculated The H2-antagonists, cimetidine (I) [51481-61-9] and metiamide [34839-70-8] had no effect on the lipid phase transition temperatures
Biochemical Pharmacology published new progress about 2508-72-7. 2508-72-7 belongs to imidazoles-derivatives, auxiliary class Inhibitor,Immunology/Inflammation,Histamine Receptor, name is N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride, and the molecular formula is C17H20ClN3, Safety of N-Benzyl-N-((4,5-dihydro-1H-imidazol-2-yl)methyl)aniline hydrochloride.
Referemce:
https://en.wikipedia.org/wiki/Imidazole,
Imidazole | C3H4N2 – PubChem