Horwitz, Steven M. et al. published their research in Journal of the National Comprehensive Cancer Network in 2022 | CAS: 16506-27-7

4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Formula: C16H21Cl2N3O2

T-cell lymphomas, version 2.2022 was written by Horwitz, Steven M.;Ansell, Stephen;Ai, Weiyun Z.;Barnes, Jeffrey;Barta, Stefan K.;Brammer, Jonathan;Clemens, Mark W.;Dogan, Ahmet;Foss, Francine;Ghione, Paola;Goodman, Aaron M.;Guitart, Joan;Halwani, Ahmad;Haverkos, Bradley M.;Hoppe, Richard T.;Jacobsen, Eric;Jagadeesh, Deepa;Jones, Allison;Kallam, Avyakta;Kim, Youn H.;Kumar, Kiran;Mehta-Shah, Neha;Olsen, Elise A.;Rajguru, Saurabh A.;Rozati, Sima;Said, Jonathan;Shaver, Aaron;Shea, Lauren;Shinohara, Michi M.;Sokol, Lubomir;Torres-Cabala, Carlos;Wilcox, Ryan;Wu, Peggy;Zain, Jasmine;Dwyer, Mary;Sundar, Hema. And the article was included in Journal of the National Comprehensive Cancer Network in 2022.Formula: C16H21Cl2N3O2 The following contents are mentioned in the article:

Peripheral T-cell lymphomas (PTCLs) are a heterogeneous group of lymphoproliferative disorders arising from mature T cells, accounting for about 10% of non-Hodgkin lymphomas. PTCL-not otherwise specified is the most common subtype, followed by angioimmunoblastic T-cell lymphoma, anaplastic large cell lymphoma, anaplastic lymphoma kinase-pos., anaplastic large cell lymphoma, anaplastic lymphoma kinase-neg., and enteropathy-associated T-cell lymphoma. This discussion section focuses on the diagnosis and treatment of PTCLs as outlined in the NCCN Guidelines for T-Cell Lymphomas. This study involved multiple reactions and reactants, such as 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7Formula: C16H21Cl2N3O2).

4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7) belongs to imidazole derivatives. Imidazole is a heterocyclic compound with a five-membered planar ring. It is amphoteric and highly polar. Imidazole is incorporated into many important biological compounds. The most pervasive is the amino acid histidine, which has an imidazole side-chain. Histidine is present in many proteins and enzymes, e.g. by binding metal cofactors, as seen in hemoglobin.Formula: C16H21Cl2N3O2

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem