Yoshida, Isao et al. published their research in Ketsueki Naika in 2021 | CAS: 16506-27-7

4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Related Products of 16506-27-7

Treatment strategy for patients with relapsed/refractory classical Hodgkin lymphoma was written by Yoshida, Isao. And the article was included in Ketsueki Naika in 2021.Related Products of 16506-27-7 The following contents are mentioned in the article:

A review. Classical Hodgkin lymphoma (CHL) is a type of lymphoma that is sensitive to chemotherapy and can provide an R-stage solution in many cases. Single-center pre-examination study of combination treatment with bendamustine, nivolumab for patients who became refractory to treatment with nivolumab. It will be performed in consideration of the disease, organ function, and the drug packing used in the previous treatment, but if the reduction effect is obtained by the rescue chemotherapy, the self-implantation combined large-scale chemotherapeutic method (ASCT) is used as a remedy treatment. This review outlines the treatment of relapsed/refractory classical Hodgkin lymphoma with a focus on brentuximab vedotin and ΡD-1 antibodies, and the usefulness of autologous stem cell transplant in therapeutic cases. This study involved multiple reactions and reactants, such as 4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7Related Products of 16506-27-7).

4-(5-(Bis(2-chloroethyl)amino)-1-methyl-1H-benzo[d]imidazol-2-yl)butanoic acid (cas: 16506-27-7) belongs to imidazole derivatives. Imidazole derivatives generally have good solubility in protic solvents. Simple imidazole derivatives, such as 1H-imidazole, 2-methyl-1H-imidazole, and 1,2-dimethylimidazole, have very high solubility in water. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Related Products of 16506-27-7

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem