Acidic ionic liquid-catalyzed highly efficient reaction of indoles to α,β-unsaturated ketones was written by Gu, Da-gong;Ji, Shun-jun;Wang, Hong-xia;Xu, Qiu-yan. And the article was included in Synthetic Communications in 2008.Recommanded Product: 478935-29-4 The following contents are mentioned in the article:
A novel method for the Michael reaction of indoles to α,β-unsaturated ketones catalyzed by acidic ionic liquid was reported. The authors obtained the corresponding products in excellent yields in the presence of [hmim]HSO4. Development of this method resulted in a new protocol for the synthesis of β-indolylketones. This study involved multiple reactions and reactants, such as 1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4Recommanded Product: 478935-29-4).
1-Hexyl-3-methyl-1H-imidazol-3-ium hydrogensulfate (cas: 478935-29-4) belongs to imidazole derivatives. Imidazole is the basic core of some natural products such as histidine, purine, histamine and DNA based structures, etc. Among the different heterocyclic compounds, imidazole is better known due to its broad range of chemical and biological properties. The pharmacophore of imidazole exists in bioactive compounds including amino acids, plant growth regulators and therapeutic agents.n increase of the alkyl chain length of the alcohols. Recommanded Product: 478935-29-4
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem