Reference of 288-32-4, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 288-32-4, name is 1H-Imidazole, This compound has unique chemical properties. The synthetic route is as follows.
General procedure: In a 25 cm3 round bottomed flask, 0.20 mol% of ruthenium(II) catalyst, 2 mmol of alcohol and amine substrates, 15 mol% of potassium tert-butoxide (KtBuO) were placed and dissolved in 2.0 cm3 of toluene. The reaction flask was kept at 120 C for 12 h in an oil bath. Upon completion of reaction (monitored by TLC), the solvent was removed under vacuum and the resulting residue was purified by column chromatography on silica gel using ethylacetate/n-hexane. The amide products were dried overnight under vacuum. The resulting amides were identified by comparison of the 1H and 13C NMR data with those previously reported (ESI? )
The chemical industry reduces the impact on the environment during synthesis 1H-Imidazole. I believe this compound will play a more active role in future production and life.
Reference:
Article; Selvamurugan, Sellappan; Ramachandran, Rangasamy; Prakash, Govindan; Nirmala, Muthukumaran; Viswanathamurthi, Periasamy; Fujiwara, Shoji; Endo, Akira; Inorganica Chimica Acta; vol. 454; (2017); p. 46 – 53;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem