570-22-9,Some common heterocyclic compound, 570-22-9, name is 1H-Imidazole-4,5-dicarboxylic acid, molecular formula is C5H4N2O4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
The synthesis method is as follows: In a 100 ml single-mouth flask, add 2.85g (10mmol) dehydroabietylamine, 1.87g (12mmol) imidazol-4,5-dicarboxylic acid (molar ratio of 1:1.2) and 50 ml of toluene. 110 C reflux condenser reaction 8h. After the reaction heat filter, steaming and obtaining white solid, quality is 2.0329g, yield of 46.1%.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1H-Imidazole-4,5-dicarboxylic acid, its application will become more common.
Reference:
Patent; Nanjing Forestry University; Xu, Li; Zhao, Fengyi; Xu, Yuanyuan; Yang, Shilong; Sun, Li; Wang, Luna; Wang, Weifan; (9 pag.)CN105037191; (2017); B;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem