Cignarella, Giogrio’s team published research in Journal of Medicinal Chemistry in 1965 | CAS: 274-78-2

Journal of Medicinal Chemistry published new progress about Analgesics. 274-78-2 belongs to class imidazoles-derivatives, name is Imidazo[1,2-c]pyrimidine, and the molecular formula is C6H5N3, Synthetic Route of 274-78-2.

Cignarella, Giogrio published the artcileBicyclic homologs of piperazine. VII. Synthesis and analgesic activity of 3-aralkenyl-8-propionyl-3,8-diazabicyclo[3.2.1]octanes, Synthetic Route of 274-78-2, the main research area is ANALGESICS AND ANTIPYRETICS; BRIDGED COMPOUNDS; CHEMISTRY, PHARMACEUTICAL; EXPERIMENTAL LAB STUDY; MICE; PHARMACOLOGY; RATS; TOXICOLOGIC REPORT.

cf. CA 59, 11490g, 15283g. With the aim of enhancing the analgesic activity of 3-cinnamyl-8-propionyl-3,8-diazabicyclo[3.2.1] octane (I), 25 derivatives were synthesized in which the 3-aralkenyl group was variously modified. Some of these compounds exhibited an analgesic potency comparable with that of I.

Journal of Medicinal Chemistry published new progress about Analgesics. 274-78-2 belongs to class imidazoles-derivatives, name is Imidazo[1,2-c]pyrimidine, and the molecular formula is C6H5N3, Synthetic Route of 274-78-2.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem