Abignente, Enrico’s team published research in Farmaco in 1991-10-31 | CAS: 274-78-2

Farmaco published new progress about Analgesics. 274-78-2 belongs to class imidazoles-derivatives, name is Imidazo[1,2-c]pyrimidine, and the molecular formula is C6H5N3, COA of Formula: C6H5N3.

Abignente, Enrico published the artcileResearch on heterocyclic compounds. XXVIII. Imidazo[1,2-c]pyrimidines, COA of Formula: C6H5N3, the main research area is imidazopyridine derivative antipyretic antiinflammatory analgesic structure; ulcer formation imidazopyrimidine derivative structure.

A group of 24 imidazo[1,2-c]pyrimidines (I, R1 = CO2H, CO2Et, CONH2, CH2CO2H; R2 = Me, OMe; R3 = OMe, Me, Cl) was taken into consideration to study the relationships between chem. structure and anti-inflammatory activity. Some of these compounds were synthesized by the authors in the past, the others have been synthesized and characterized to complete the series. Anti-inflammatory, analgesic, antipyretic and gastric ulcerogenic activities of such compounds were compared with those of indomethacin and discussed in terms of the effects exerted by the presence on the heterocyclic system of various substituents and an acidic or nonacidic moiety.

Farmaco published new progress about Analgesics. 274-78-2 belongs to class imidazoles-derivatives, name is Imidazo[1,2-c]pyrimidine, and the molecular formula is C6H5N3, COA of Formula: C6H5N3.

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem