Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 53710-78-4, name is 1-(3-Chloropropyl)-1H-imidazole, This compound has unique chemical properties. The synthetic route is as follows., COA of Formula: C6H9ClN2
General procedure: To a 25mL flask was added 6-bromo-2H-benzo[b][1,4]oxazin-3(4H)-one (0.46 g, 2mmol), 4-(2-chloroethyl)morpholine (0.30 g, 2mmol), potassiumcarbonate (0.42 g, 3mmol) and DMF (8 mL), the reaction mixturewas heated at 60 C and stirred for 6 h. After the reaction was completed,the DMF was removed at reduced pressure and the residue was purified onsilica gel with chloroform/methanol (V:V 100:1) to give the title compoundas awhite powder. Yield 94.1%, m.p. 80-82 C. 1H NMR (600MHz,DMSO-d6) delta 7.51 (d, J=2.2 Hz, 1H, Ar-H), 7.17 (dd, J=8.5, 2.2Hz, 1H,Ar-H), 6.97 (d, J=8.5 Hz, 1H, Ar-H), 4.65 (s, 2H, Ar-H), 4.02 (t,J=6.4Hz, 2H, CH2), 3.53 (s, 4H, CH2¡Á2), 2.47 (t, J=6.4 Hz, 2H, CH2),2.43 (s, 4H, CH2¡Á2). ESI-MS: m/z 341.0 [M+H]+.Compounds 2b-j were synthesized according to the procedure describedin 2a.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 53710-78-4.
Reference:
Article; Dong, Fu-Dan; Liu, Dan-Dan; Deng, Cheng-Long; Qin, Xiao-chun; Chen, Kai; Wang, Jian; Song, Hong-Rui; Ding, Huai-Wei; Bioorganic and Medicinal Chemistry; vol. 26; 14; (2018); p. 3982 – 3991;,
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem