Llona-Minguez, Sabin published the artcileVinylic MIDA Boronates: New Building Blocks for the Synthesis of Aza-Heterocycles, Related Products of imidazoles-derivatives, the main research area is haloarene MIDA boronate palladium catalyst Suzuki Miyaura coupling reaction; nitro vinylarene preparation Cadogan Sundberg reductive cyclization; aza heterocycle preparation; MIDA; aminophosphonate; boronate; cyclization; heterocycles; nitrene.
A two-step synthesis of structurally diverse pyrrole-containing bicyclic systems was reported. ortho-Nitro-haloarenes coupled with vinylic N-methyliminodiacetic acid (MIDA) boronates generated ortho-vinyl-nitroarenes, which underwent a ‘metal-free’ nitrene insertion, resulted in a new pyrrole ring. The Synthetic approach has a wide substrate tolerance and it was applicable in the preparation of more complex ‘drug-like’ mols. An ortho-nitro-allylarenes furnished a cyclic β-aminophosphonate motif.
Chemistry – A European Journal published new progress about Aryl halides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 18874-52-7 belongs to class imidazoles-derivatives, name is 5-Bromo-2-methyl-4-nitroimidazole, and the molecular formula is C4H4BrN3O2, Related Products of imidazoles-derivatives.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem