On October 31, 2021, Li, Xuwen; Zhang, Zijian; Luo, Xinlong; Schrier, Jacob; Yang, Andrew D.; Wu, Tao P. published an article.Application In Synthesis of N-Methyl-7H-purin-6-amine The title of the article was The exploration of N6-deoxyadenosine methylation in mammalian genomes. And the article contained the following:
A review. N6-methyladenine (N6-mA, m6dA, or 6mA), a prevalent DNA modification in prokaryotes, has recently been identified in higher eukaryotes, including mammals. Although 6mA has been well-studied in prokaryotes, the function and regulatory mechanism of 6mA in eukaryotes are still poorly understood. Recent studies indicate that 6mA can serve as an epigenetic mark and play critical roles in various biol. processes, from transposable-element suppression to environmental stress response. Here, we review the significant advances in methodol. for 6mA detection and major progress in understanding the regulation and function of this non-canonical DNA methylation in eukaryotes, predominantly mammals. The experimental process involved the reaction of N-Methyl-7H-purin-6-amine(cas: 443-72-1).Application In Synthesis of N-Methyl-7H-purin-6-amine
The Article related to review dna methylation mammalian genome, dna n6-methyladenine (6ma), mammalian dna modification, non-canonical mammalian dna methylation, Biochemical Genetics: Reviews and other aspects.Application In Synthesis of N-Methyl-7H-purin-6-amine
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem