On March 16, 2018, Delsarte, Christine; Santraine, Romuald; Fours, Baptiste; Petit, Laurent published an article.Name: 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole The title of the article was Metal-Free Synthesis of the Methanol Solvate of (S)-Omeprazole Potassium Salt Using (1R)-(-)-10-Camphorsulfonyloxaziridine: Oxidation Process Development and Optical Purity Enhancement Strategy. And the article contained the following:
The results of our process development studies to synthesize the methanol solvate of (S)-omeprazole potassium salt through the enantioselective oxidation of pyrmetazole using (1R)-(-)-10-camphorsulfonyloxaziridine are reported. Optical purity enhancement was achieved by means of a reslurry from methanol, the rationale and development details of which are also described. The experimental process involved the reaction of 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole(cas: 73590-85-9).Name: 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole
The Article related to pyrmetazole camphorsulfonyloxaziridine enantioselective oxidation, omeprazole potassium salt stereoselective preparation, Heterocyclic Compounds (More Than One Hetero Atom): Imidazoles and other aspects.Name: 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem