Harris, Anthony R.; Nason, Deane M.; Collantes, Elizabeth M.; Xu, Wenjian; Chi, Yushi; Wang, Zhihan; Zhang, Bingzhi; Zhang, Qingjian; Gray, David L.; Davoren, Jennifer E. published an article in 2011, the title of the article was Synthesis of 5-bromo-6-methyl imidazopyrazine, 5-bromo and 5-chloro-6-methyl imidazopyridine using electron density surface maps to guide synthetic strategy.Safety of 5-Bromo-6-methylimidazo[1,2-a]pyridine And the article contains the following content:
Small heteroaromatic rings are valuable monomers in drug discovery that can enable rapid access to novel and desirable chem. space. Installation of a synthetic handle on a heteroaromatic core may be difficult if steric and electronic factors are not in alignment with the desired transformation. Described are practical routes for the construction of 5-bromo-6-Me imidazopyrazine I as well as Me imidazopyridines, e.g., II, developed using electron d. surface maps encoded with ionization potential to guide synthetic strategy. The experimental process involved the reaction of 5-Bromo-6-methylimidazo[1,2-a]pyridine(cas: 1346157-13-8).Safety of 5-Bromo-6-methylimidazo[1,2-a]pyridine
The Article related to bromomethyl imidazopyrazine preparation, methyl imidazopyridine preparation reaction mechanism, Heterocyclic Compounds (More Than One Hetero Atom): Pyrazines and Quinoxalines (Including Piperazines) and other aspects.Safety of 5-Bromo-6-methylimidazo[1,2-a]pyridine
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem