Imidazole Biochem/physiol Actions: Imidazole derivatives have antibacterial, antifungal and anticancer functionality. It interacts with DNA and also binds to protein and stops cell division. 10111-08-7, formula is C4H4N2O, Name is 1H-Imidazole-2-carbaldehyde. It also acts as a microtubule destabilizing agents and inhibits topoisomerase and Cytochrome P450 Family 26 Subfamily A Member 1 (CYP26A1) enzymes. Formula: C4H4N2O.
Naidu, Bandameeda Ramesh;Lakshmidevi, Jangam;Naik, Bukke Siva Sankar;Venkateswarlu, Katta research published 《 Water extract of pomegranate ash as waste-originated biorenewable catalyst for the novel synthesis of chiral tert-butanesulfinyl aldimines in water》, the research content is summarized as follows. Renewable materials-catalyzed reactions in aqueous media are urgently needed and highly fascinating tasks in the current state of organic synthesis. Here, we report a novel and sustainable protocol for the biorenewable, waste-originated water extract of pomegranate ash (WEPA) catalyzed condensation reaction of tert-butanesulfinamides and aldehydes in water to produce chiral tert-butanesulfinyl aldimines (tBSAIs) in high yields. The products are separated by filtration and purified by recrystallization, avoiding extraction and column chromatog. separation steps. The reaction was performed with high yields in several consecutive recycles of the catalyst and medium; and further, this method is highly effective for the multi-gram scale synthesis of tBSAIs. The application of biorenewable catalyst, added metal/catalyst-free conditions, absence of volatile organic solvents and additives, vast substrate feasibility, economical profiles, easy operation, reusability of the catalyst, large scale viability, non-chromatog. purification of products, and tremendous future perspective are the sparkling insights of this development.
Formula: C4H4N2O, 1H-Imidazole-2-carbaldehyde, also known as 1H-Imidazole-2-carbaldehyde, is a useful research compound. Its molecular formula is C4H4N2O and its molecular weight is 96.09 g/mol. The purity is usually 95%.
1H-Imidazole-2-carboxaldehyde is a novel PTP1b inhibitor with potential application to treat type 2 diabetes.
1H-Imidazole-2-carboxaldehyde is a broad-spectrum antimicrobial that has been shown to inhibit the growth of bacteria by interfering with protein synthesis. It binds to the cytosolic protein and receptor molecule, which are involved in the activation of bacterial enzymes. Imidazole-2-carboxaldehyde reacts with anhydrous sodium and copper complex to produce hydrogen bonds, which prevent the formation of the nitrogen atoms necessary for cellular processes. This chemical also has biological properties such as glyoxal, which inhibits bacterial growth by reacting with amino groups on proteins., 10111-08-7.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem