Liu, Yaxu’s team published research in European Journal of Inorganic Chemistry in 2022 | CAS: 141556-45-8

1,3-Dimesityl-1H-imidazol-3-ium chloride(cas: 141556-45-8) is a ligand for arylation of aldehydes and for carbene catalyzed intermolecular arylation of C-H bonds. It is used as a phosphine-free ligand in various metal-catalyzed coupling reactions, often with advantageous results in difficult cases.Recommanded Product: 1,3-Dimesityl-1H-imidazol-3-ium chloride

In 2022,Liu, Yaxu; Scattolin, Thomas; Gobbo, Alberto; Belis, Marek; Van Hecke, Kristof; Nolan, Steven P.; Cazin, Catherine S. J. published an article in European Journal of Inorganic Chemistry. The title of the article was 《A Simple Synthetic Route to Well-Defined [Pd(NHC)Cl(1-tBu-indenyl)] Pre-catalysts for Cross-Coupling Reactions》.Recommanded Product: 1,3-Dimesityl-1H-imidazol-3-ium chloride The author mentioned the following in the article:

A simple synthetic access to [Pd(NHC)Cl(1-tBu-indenyl)] complexes bearing different saturated and unsaturated NHC ligands was reported. All complexes were obtained in excellent yields under mild conditions (60°C, 1 h) in the presence of the weak base K2CO3 in green acetone as the solvent. We view synthetic access as vital in delineating the precatalyst choice and have demonstrated here the facile access to these complexes was reported. The catalytic activity of the synthesized derivatives were investigated on three different cross-coupling reactions such as Suzuki-Miyaura, unconventional Suzuki-Miyaura reaction and Buchwald-Hartwig amination to form Ar1Ar2 [Ar1 = Ph, 4-MeC6H4, 4-FC6H4, etc.; Ar2 = Ph, 4-MeOC6H4, 4-MeC6H4, etc.], and PhC(O)Ar [Ar = Ph, 3-MeOC6H4, 4-MeC6H4, etc.], R1NR2R3 [R1 = 4-OMe, 4-CF3; R2 = Ph, R3 = Me; R2R3 = CH2CH2OCH2CH2] resp.. Complex [Pd(IPr*)Cl(1-tBu-indenyl)], which borne the less electron-donating IPrCl ligand, showed the best performance on conventional Suzuki-Miyaura reaction of (aryl chlorides/arylboronic acids) and Buchwald-Hartwig amination using MeOH/THF and the green 2-MeTHF as solvents, resp. Moreover, for the challenging unconventional Suzuki-Miyaura reaction between esters and arylboronic acids, [Pd(IPr*)Cl(1-tBu-indenyl)] showed the highest activity among all catalysts tested. In the experiment, the researchers used 1,3-Dimesityl-1H-imidazol-3-ium chloride(cas: 141556-45-8Recommanded Product: 1,3-Dimesityl-1H-imidazol-3-ium chloride)

1,3-Dimesityl-1H-imidazol-3-ium chloride(cas: 141556-45-8) is a ligand for arylation of aldehydes and for carbene catalyzed intermolecular arylation of C-H bonds. It is used as a phosphine-free ligand in various metal-catalyzed coupling reactions, often with advantageous results in difficult cases.Recommanded Product: 1,3-Dimesityl-1H-imidazol-3-ium chloride

Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem