Reference of 1H-Imidazol-2-amineIn 2021 ,《Synthesis and molecular docking of some new 3,5-bis-(diazepine, pyrazolopyrimidine, pyrimidine, and pyrazole) pyridine derivatives and their in vitro and in vivo biological evaluation as potential antitumor agents》 appeared in Journal of Heterocyclic Chemistry. The author of the article were Soliman, Nanees N.; Tag, Yasmin M.; Bayoumy, Nesma M.. The article conveys some information:
Dihydropyridine-containing bisenaminone I was used to synthesize new heterocyclic compounds containing nitrogen moieties, such as II (R = H, Me, Ph, H2N, 6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl) by reaction with different bifunctional reagents. Moreover, the new compounds were screened in vitro as antitumor agents for Ehrlich ascites at different concentrations The results showed that selected compounds such as II (R = H) had good activity. In addition the mol. docking of these mentioned compounds was studied using vascular endothelial growth factor receptor. In addition to this study using 1H-Imidazol-2-amine, there are many other studies that have used 1H-Imidazol-2-amine(cas: 7720-39-0Reference of 1H-Imidazol-2-amine) was used in this study.
1H-Imidazol-2-amine(cas: 7720-39-0) belongs to anime. Amines can be classified according to the nature and number of substituents on nitrogen. Aliphatic amines contain only H and alkyl substituents. Aromatic amines have the nitrogen atom connected to an aromatic ring.Important amines include amino acids, biogenic amines, trimethylamine, and aniline. Inorganic derivatives of ammonia are also called amines, such as monochloramine (NClH2).Reference of 1H-Imidazol-2-amine
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem