In 1973,Journal of General Microbiology included an article by Stutzenberger, F. J.; Parle, J. N.. Application In Synthesis of 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol. The article was titled 《Effect of 2-substituted benzimidazoles on the fungus Pithomyces chartarum》. The information in the text is summarized as follows:
The inhibition of germ-tube elongation in P. chartarum conidia by 2-substituted benzimidazoles varied markedly with the substituted group, 2-(4-thiazolyl)benzimidazole (I) [148-79-8] being the most active. I inhibition of germ-tube elongation was partially eliminated by high concentrations of vitamin B12 [68-19-9], suggesting that I may act as a precursor in the formation of an inactive vitamin B12 coenzyme analog. The inhibition of respiration in germinating spores exposed to I for 3-4 hr appeared to be an indirect effect of I, since I did not affect O uptake or respiratory control of isolated mitochondria. In the experiment, the researchers used 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol(cas: 2403-66-9Application In Synthesis of 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol)
3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol(cas: 2403-66-9) belongs to imidazoles.Imidazole rings are also present in imidazole ring alkaloids, which are potential therapeutics for thrombosis, cancer and inflammatory diseases.Application In Synthesis of 3-(1H-Benzo[d]imidazol-2-yl)propan-1-ol Although other azole heterocycles are ubiquitous in a wide range of biologically active natural products, imidazole rings occur predominantly in the natural amino acid histidine.
Referemce:
Imidazole – Wikipedia,
Imidazole | C3H4N2 – PubChem